Search Results - "You, Xin‐yu"
-
1
Bidirectional Brain‐gut‐microbiota Axis in increased intestinal permeability induced by central nervous system injury
Published in CNS neuroscience & therapeutics (01-08-2020)“…Central nervous system injuries may lead to the disorders of the hypothalamic‐pituitary‐adrenal axis, autonomic nervous system, and enteric nervous system…”
Get full text
Journal Article -
2
Development and evaluation of a simple and easy high‐performance liquid chromatography–ultraviolet system simultaneously suitable for determination of 24 anti‐epileptic drugs in plasma
Published in Journal of separation science (01-07-2022)“…We aim to establish a simple and easy high‐performance liquid chromatography system coupled with an ultraviolet detector suitable for simultaneous…”
Get full text
Journal Article -
3
Fabrication of a surface molecularly imprinted polymer membrane based on a single template and its application in the separation and extraction of phenytoin, phenobarbital and lamotrigine
Published in RSC advances (06-03-2024)“…An innovative molecularly imprinted polymer membrane (MIPM) was prepared with polyvinylidene difluoride (PVDF) as the support, phenytoin (PHT) as the single…”
Get full text
Journal Article -
4
A simple and easy non‐derivatization gas chromatography‐mass spectrometry method for simultaneous quantification of valproic acid, gabapentin, pregabalin, and vigabatrin in human plasma
Published in Journal of separation science (01-01-2023)“…Immunoassays are currently not available in commercial kits for the quantification of valproic acid, vigabatrin, pregabalin, and gabapentin, which also cannot…”
Get full text
Journal Article -
5
Global potential energy surface survey of pentanitrogen cation
Published in Molecular physics (17-07-2024)“…We reported hitherto the most extensive isomeric, interconversion and decomposition landscape of the pentanitrogen cation (N 5 + ) at the…”
Get full text
Journal Article -
6
Intestinal Mucosal Barrier Is Regulated by Intestinal Tract Neuro-Immune Interplay
Published in Frontiers in pharmacology (31-05-2021)“…Inflammatory bowel disease, irritable bowel syndrome and severe central nervous system injury can lead to intestinal mucosal barrier damage, which can cause…”
Get full text
Journal Article -
7
Development of magnetic molecularly imprinted polymers with double templates for the rapid and selective determination of carbamazepine and lamotrigine in serum
Published in RSC advances (25-03-2022)“…A dual-template magnetic molecularly imprinted polymer (Dt-MMIP) with a specific recognition capability for carbamazepine (CBZ) and lamotrigine (LTG) was…”
Get full text
Journal Article -
8
Enantioselective Synthesis of Axially Chiral Biaryls by Diels–Alder/Retro-Diels–Alder Reaction of 2‑Pyrones with Alkynes
Published in Journal of the American Chemical Society (23-06-2021)“…The enantioselective synthesis of axially chiral biaryls by a copper-catalyzed Diels–Alder/retro-Diels–Alder reaction of 2-pyrones with alkynes is reported…”
Get full text
Journal Article -
9
Functional characterization of an arrestin gene on insecticide resistance of Culex pipiens pallens
Published in Parasites & vectors (06-07-2012)“…BACKGROUND: Continuous and excessive application of insecticides has resulted in the rapid development of insecticide resistance in several mosquito species,…”
Get full text
Journal Article -
10
Enrichment and immobilization of heavy metal ions from wastewater by nanocellulose/carbon dots-derived composite
Published in International journal of biological macromolecules (01-01-2024)“…Heavy metal ions (HMIs) have been widely applied in various industries because of their excellent physicochemical properties. However, their discharging…”
Get full text
Journal Article -
11
( E )-3-Dimethylamino-1-(1,3-thiazol-2-yl)prop-2-en-1-one
Published in Acta crystallographica. Section E, Structure reports online (01-01-2013)“…In the title compound, C8H10N2OS, the 3-(dimethylamino)prop-2-en-1-one unit is approximately planar [give r.m.s. deviation] and the mean plane through the…”
Get full text
Journal Article -
12
Molecularly imprinted polymer membranes based on single template for recognition and extraction of carbamazepine and its structurally analogues
Published in Microchemical journal (01-12-2023)“…[Display omitted] •A novel MIPM was synthesized and characterized.•The MIPM utilized surface imprinting and free radical polymerization.•The preparation method…”
Get full text
Journal Article -
13
Effects of UGT1A , CYP2C9/19 and ABAT polymorphisms on plasma concentration of valproic acid in Chinese epilepsy patients
Published in Pharmacogenomics (01-02-2023)“…To evaluate the association between genetic polymorphisms and plasma concentration-to-dose ratio of valproic acid (CDRV) in Chinese epileptic patients. A total…”
Get full text
Journal Article -
14
Synthesis and antitubercular evaluation of 4-carbonyl piperazine substituted 1,3-benzothiazin-4-one derivatives
Published in Bioorganic & medicinal chemistry letters (01-04-2015)“…[Display omitted] Tuberculosis (TB) remains a major human health problem. New therapeutic antitubercular agents are urgent needed to control the global…”
Get full text
Journal Article -
15
Discovery and structure–activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors
Published in Bioorganic & medicinal chemistry letters (15-03-2014)“…SAR investigation on five regions of thieno[2,3-b]pyridine derivatives led to the discovery of several promising compounds which exhibited low micromolar…”
Get full text
Journal Article -
16
Synthesis and structure–activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents
Published in Bioorganic & medicinal chemistry letters (01-09-2013)“…The synthesis and SAR profile of N-alkyl and heterocycle substituted 1,3-benzothiazin-4-one (BTZ) derivatives are described. The most potent compound 8o…”
Get full text
Journal Article -
17
Clinical features and genetic analysis of developmental and epileptic encephalopathy caused by biallelic variants of CACNA1B
Published in Heliyon (30-06-2024)“…To analyze the clinical features and genetic etiology of a patient with developmental and epileptic encephalopathy. The clinical information and peripheral…”
Get full text
Journal Article -
18
Discovery of Imidazo[2,1‑b]thiazole HCV NS4B Inhibitors Exhibiting Synergistic Effect with Other Direct-Acting Antiviral Agents
Published in Journal of medicinal chemistry (26-03-2015)“…The design, synthesis, and SAR studies of novel inhibitors of HCV NS4B based on the imidazo[2,1-b]thiazole scaffold were described. Optimization of potency…”
Get full text
Journal Article -
19
Discovery of novel N-(5-(tert-butyl)isoxazol-3-yl)-N′-phenylurea analogs as potent FLT3 inhibitors and evaluation of their activity against acute myeloid leukemia in vitro and in vivo
Published in Bioorganic & medicinal chemistry (01-08-2015)“…[Display omitted] FLT3 inhibitors have been explored as a viable therapy for acute myeloid leukemia (AML). However, the clinical outcomes of these FLT3…”
Get full text
Journal Article -
20
A novel benzothiazinethione analogue SKLB-TB1001 displays potent antimycobacterial activities in a series of murine models
Published in Biomedicine & pharmacotherapy (01-04-2017)“…Abstract New chemotherapeutic compounds and regimens are needed to combat multidrug-resistant Mycobacterium tuberculosis . Here, we used a series of murine…”
Get full text
Journal Article