Search Results - "You, Bo Ra"

Suberoylanilide hydroxamic acid induces thioredoxin1‐mediated apoptosis in lung cancer cells via up‐regulation of miR‐129‐5p by You, Bo Ra, Park, Woo Hyun

“…Histone deacetylase (HDAC) inhibitors, especially suberoylanilide hydroxamic acid (SAHA) induce apoptosis in various cancer cells. Here, we investigated the…”
Get full text

Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase by You, Bo Ra, Park, Woo Hyun

“…Gallic acid (GA) widely distributed in plants and foods has its various biological effects. Here, we investigated the anti-cancer effects of GA on Calu-6 and…”
Get full text

Reactive oxygen species, glutathione, and thioredoxin influence suberoyl bishydroxamic acid-induced apoptosis in A549 lung cancer cells by You, Bo Ra, Kim, Suhn Hee, Park, Woo Hyun

“…Suberoyl bishydroxamic acid (SBHA) as a histone deacetylase (HDAC) inhibitor can induce apoptosis through the formation of reactive oxygen species (ROS)…”
Get full text

Zebularine-induced apoptosis in Calu-6 lung cancer cells is influenced by ROS and GSH level changes by You, Bo Ra, Park, Woo Hyun

“…Zebularine (Zeb) is a DNA methyltransferase (DNMT) inhibitor that has various biological properties including anti-cancer effect. In the present study, we…”
Get full text

Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis by You, Bo Ra, Park, Woo Hyun

“…Zebularine (Zeb) as a DNA methyltrasferase (DNMT) inhibitor has various cellular effects such as cell growth inhibition and apoptosis. In the present study, we…”
Get full text

Suberoyl bishydroxamic acid inhibits the growth of A549 lung cancer cells via caspase-dependent apoptosis by You, Bo Ra, Park, Woo Hyun

“…Suberoyl bishydroxamic acid (SBHA) as a histone deacetylase (HDAC) inhibitor has various cellular effects such as cell growth and apoptosis. In the present…”
Get full text

Enhancement of gallic acid-induced human pulmonary fibroblast cell death by N-acetyl cysteine and L-buthionine sulfoximine by You, Bo Ra, Park, Woo Hyun

“…Gallic acid (GA) has various biological properties including anti-cancer effect. However, little is known about the toxicological effect of GA in primary…”
Get more information

PX-12 induces apoptosis in Calu-6 cells in an oxidative stress-dependent manner by You, Bo Ra, Shin, Hye Rim, Han, Bo Ram, Park, Woo Hyun

Get full text

MG132, A Proteasome Inhibitor, Induced Death of Calf Pulmonary Artery Endothelial Cells via Caspase-dependent Apoptosis and GSH Depletion by Han, Yong Hwan, Moon, Hwa Jin, You, Bo Ra, Yang, Yeon Mi, Kim, Sung Zoo, Kim, Suhn Hee, Park, Woo Hyun

“…MG132, a proteasome inhibitor, has been shown to induce apoptotic cell death through formation of reactive oxygen species (ROS). Here, we evaluated the effects…”
Get full text

Agonist-induced 4-1BB activation prevents the development of Sjӧgren's syndrome-like sialadenitis in non-obese diabetic mice by Zhou, Jing, You, Bo Ra, Yu, Qing

“…Activation of costimulatory receptor 4-1BB enhances T helper 1 (Th1) and CD8 T cell responses in protective immunity, and prevents or attenuates several…”
Get full text

Down-Regulation of Thioredoxin1 Is Involved in Death of Calu-6 Lung Cancer Cells Treated With Suberoyl Bishydroxamic Acid by You, Bo Ra, Park, Woo Hyun

“…ABSTRACT Suberoyl bishydroxamic acid (SBHA), a histone deacetylase (HDAC) inhibitor, can show an anticancer effect. In this study, we investigated the effects…”
Get full text

Zebularine inhibits the growth of A549 lung cancer cells via cell cycle arrest and apoptosis by You, Bo Ra, Park, Woo Hyun

“…Zebularine (Zeb) is a DNA methyltransferase (DNMT) inhibitor to that has an anti‐tumor effect. Here, we evaluated the anti‐growth effect of Zeb on A549 lung…”
Get full text

Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-α through up-regulation of TNF receptor 1 in lung cancer cells by You, Bo Ra, Han, Bo Ram, Park, Woo Hyun

“…Suberoylanilide hydroxamic acid (SAHA) as a histone deacetylase (HDAC) inhibitor has anti-cancer effect. Here, we evaluated the effect of SAHA on HDAC activity…”
Get full text

Gallic acid-induced lung cancer cell death is accompanied by ROS increase and glutathione depletion by You, Bo Ra, Kim, Sung Zoo, Kim, Suhn Hee, Park, Woo Hyun

“…Gallic acid (GA) is generally distributed in a variety of plants and foods, and its various biological effects have been reported. Here, we investigated the…”
Get full text

Gallic acid inhibits the growth of HeLa cervical cancer cells via apoptosis and/or necrosis by You, Bo Ra, Moon, Hwa Jin, Han, Yong Hwan, Park, Woo Hyun

“…Gallic acid (GA) is widely distributed in various plants and foods, and its various biological effects have been reported. Here, we evaluated the effects of GA…”
Get full text

Suberoyl bishydroxamic acid-induced apoptosis in HeLa cells via ROS-independent, GSH-dependent manner by You, Bo Ra, Park, Woo Hyun

“…Suberoyl bishydroxamic acid (SBHA) is a HDAC inhibitor that can regulate many biological functions including apoptosis and proliferation in various cancer…”
Get full text

PX-12 induces apoptosis in Calu-6 cells in an oxidative stress-dependent manner by You, Bo Ra, Shin, Hye Rim, Han, Bo Ram, Park, Woo Hyun

“…PX-12 (1-methylpropyl 2-imidazolyl disulfide) as a thioredoxin (Trx) inhibitor has an anti-tumor effect. However, there is no report about the toxicological…”
Get full text

The effects of antimycin A on endothelial cells in cell death, reactive oxygen species and GSH levels by You, Bo Ra, Park, Woo Hyun

“…Antimycin A (AMA) inhibits mitochondrial electron transport chain between cytochrome b and c. Here, we evaluated the effects of AMA on the growth and death of…”
Get full text

The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH by Han, Yong Hwan, Moon, Hwa Jin, You, Bo Ra, Park, Woo Hyun

“…MG132 (carbobenzoxy-Leu-Leu-leucinal) is a peptide aldehyde, which effectively blocks the proteolytic activity of the 26S proteasome complex. We evaluated the…”
Get full text

The enhancement of propyl gallate-induced HeLa cell death by MAPK inhibitors is accompanied by increasing ROS levels by You, Bo Ra, Park, Woo Hyun

“…Propyl gallate (PG) as a synthetic antioxidant exerts a variety of effects on tissue and cell functions. Here, we investigated the effects of MAPK (MEK, JNK…”
Get full text