Search Results - "Yoshiya, Taku"

A Global Review on Short Peptides: Frontiers and Perspectives by Apostolopoulos, Vasso, Bojarska, Joanna, Chai, Tsun-Thai, Elnagdy, Sherif, Kaczmarek, Krzysztof, Matsoukas, John, New, Roger, Parang, Keykavous, Lopez, Octavio Paredes, Parhiz, Hamideh, Perera, Conrad O, Pickholz, Monica, Remko, Milan, Saviano, Michele, Skwarczynski, Mariusz, Tang, Yefeng, Wolf, Wojciech M, Yoshiya, Taku, Zabrocki, Janusz, Zielenkiewicz, Piotr, AlKhazindar, Maha, Barriga, Vanessa, Kelaidonis, Konstantinos, Sarasia, Elham Mousavinezhad, Toth, Istvan

“…Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with…”
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B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction by Minato, Takafumi, Nirasawa, Satoru, Sato, Teruki, Yamaguchi, Tomokazu, Hoshizaki, Midori, Inagaki, Tadakatsu, Nakahara, Kazuhiko, Yoshihashi, Tadashi, Ozawa, Ryo, Yokota, Saki, Natsui, Miyuki, Koyota, Souichi, Yoshiya, Taku, Yoshizawa-Kumagaye, Kumiko, Motoyama, Satoru, Gotoh, Takeshi, Nakaoka, Yoshikazu, Penninger, Josef M., Watanabe, Hiroyuki, Imai, Yumiko, Takahashi, Saori, Kuba, Keiji

“…Angiotensin-converting enzyme 2 (ACE2) is critically involved in cardiovascular physiology and pathology, and is currently clinically evaluated to treat acute…”
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Solubilizing Trityl‐Type Tag To Synthesize Asx/Glx‐Containing Peptides by Tsuda, Shugo, Masuda, Shun, Yoshiya, Taku

“…A novel solubilizing tag system for Asp/Asn/Glu/Gln‐containing peptides is described. In this method, an Asp/Glu[Dbz‐Cys‐NH2]‐containing peptide (Dbz:…”
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Synthesis of Cysteine-Rich Peptides by Native Chemical Ligation without Use of Exogenous Thiols by Tsuda, Shugo, Yoshiya, Taku, Mochizuki, Masayoshi, Nishiuchi, Yuji

“…Native chemical ligation (NCL) performed without resorting to the use of thiol additives was demonstrated to be an efficient and effective procedure for…”
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A trimethyllysine-containing trityl tag for solubilizing hydrophobic peptides by Masuda, Shun, Tsuda, Shugo, Yoshiya, Taku

“…Hydrophobic membrane peptides/proteins having low water solubility are often difficult to prepare. To overcome this issue, temporal introduction of…”
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Development of Trityl Group Anchored Solubilizing Tags for Peptide and Protein Synthesis by Yoshiya, Taku, Tsuda, Shugo, Masuda, Shun

“…Recently, solubilizing tag methods (Trt‐K and Trt‐R method) were developed for the challenging synthesis of peptides/proteins by means of native chemical…”
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Cyclic homodimer formation by singlet oxygen-mediated oxidation of carnosine by Kawakami, Hiroko, Itakura, Yuki, Yamamoto, Tetsuya, Yoshiya, Taku

“…Although carnosine (β-Ala-L-His) is one of physiological protectants against damages caused by reactive oxygen species (ROS), its reactivity against singlet…”
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Imidazole-Aided Native Chemical Ligation: Imidazole as a One-Pot Desulfurization-Amenable Non-Thiol-Type Alternative to 4-Mercaptophenylacetic Acid by Sakamoto, Ken, Tsuda, Shugo, Mochizuki, Masayoshi, Nohara, Yukie, Nishio, Hideki, Yoshiya, Taku

“…Various bioactive proteins have been synthesized by native chemical ligation (NCL) and its combination with subsequent desulfurization (e.g., conversion from…”
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Dioxetane Derivative Containing Carboxy Group as a Chemiluminophore‐Introducing Reagent by Nohara, Yukie, Masuda, Shun, Kaneda‐Nakashima, Kazuko, Shirakami, Yoshifumi, Matsumoto, Masakatsu, Yoshiya, Taku

“…Some types of dioxetanes are called chemiluminophores because they produce luminescence light without the use of enzymes. Here, we designed and synthesized a…”
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Late-Stage Solubilization of Poorly Soluble Peptides Using Hydrazide Chemistry by Sato, Kohei, Tanaka, Shoko, Wang, Junzhen, Ishikawa, Kenya, Tsuda, Shugo, Narumi, Tetsuo, Yoshiya, Taku, Mase, Nobuyuki

“…A novel late-stage solubilization of peptides using hydrazides is described. A solubilizing tag was attached through a selective N-alkylation at a hydrazide…”
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Role of a bacterial glycolipid in Sec-independent membrane protein insertion by Nomura, Kaoru, Mori, Shoko, Fujikawa, Kohki, Osawa, Tsukiho, Tsuda, Shugo, Yoshizawa-Kumagaye, Kumiko, Masuda, Shun, Nishio, Hideki, Yoshiya, Taku, Yoda, Takao, Shionyu, Masafumi, Shirai, Tsuyoshi, Nishiyama, Ken-ichi, Shimamoto, Keiko

“…Non-proteinaceous components in membranes regulate membrane protein insertion cooperatively with proteinaceous translocons. An endogenous glycolipid in the…”
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Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy by Kageyama, Susumu, Ii, Hiromi, Taniguchi, Keiko, Kubota, Shigehisa, Yoshida, Tetsuya, Isono, Takahiro, Chano, Tokuhiro, Yoshiya, Taku, Ito, Kosei, Yoshiki, Tatsuhiro, Kawauchi, Akihiro, Nakata, Susumu

“…γ-Glutamylcyclotransferase (GGCT), which is one of the major enzymes involved in glutathione metabolism, is upregulated in a wide range of cancers-glioma,…”
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Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine by Aso, Ayaka, Nabetani, Hinako, Matsuura, Yoshifumi, Kadonaga, Yuichiro, Shirakami, Yoshifumi, Watabe, Tadashi, Yoshiya, Taku, Mochizuki, Masayoshi, Ooe, Kazuhiro, Kawakami, Atsuko, Jinno, Naoya, Toyoshima, Atsushi, Haba, Hiromitsu, Wang, Yang, Cardinale, Jens, Giesel, Frederik Lars, Shimoyama, Atsushi, Kaneda-Nakashima, Kazuko, Fukase, Koichi

“…Fibroblast activation proteins (FAP) are overexpressed in the tumor stroma and have received attention as target molecules for radionuclide therapy. The FAP…”
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Establishment and clinical application of SARS-CoV-2 catch column by Isaka, Yoshitaka, Yoshiya, Taku, Ono, Chikako, Uchiyama, Akinori, Hirata, Haruhiko, Hamaguchi, Shigeto, Kutsuna, Satoshi, Takabatake, Yoshitsugu, Saita, Ryotaro, Yamada, Tomomi, Takahashi, Atsushi, Yamato, Masaya, Nohara, Yukie, Tsuda, Shugo, Anzai, Itsuki, Kimura, Tomonori, Takeda, Yoshito, Tomono, Kazunori, Matsuura, Yoshiharu

“…Background A certain number of patients with coronavirus disease 2019 (COVID-19), particularly those who test positive for SARS-CoV-2 in the serum, are…”
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Intermolecular Interactions between a Membrane Protein and a Glycolipid Essential for Membrane Protein Integration by Mori, Shoko, Nomura, Kaoru, Fujikawa, Kohki, Osawa, Tsukiho, Shionyu, Masafumi, Yoda, Takao, Shirai, Tsuyoshi, Tsuda, Shugo, Yoshizawa-Kumagaye, Kumiko, Masuda, Shun, Nishio, Hideki, Yoshiya, Taku, Suzuki, Sonomi, Muramoto, Maki, Nishiyama, Ken-ichi, Shimamoto, Keiko

“…Inducing newly synthesized proteins to appropriate locations is an indispensable biological function in every organism. Integration of proteins into…”
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Nicotianamine is a novel angiotensin-converting enzyme 2 inhibitor in soybean by TAKAHASHI, Saori, YOSHIYA, Taku, YOSHIZAWA-KUMAGAYE, Kumiko, SUGIYAMA, Toshihiro

“…Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase which is highly homologous to angiotensin-converting enzyme (ACE). ACE2 produces vasodilator…”
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In Vivo Phosphorylation: Development of Specific Antibodies to Detect the Phosphorylated PEPC Isoform for the C4 Photosynthesis in Zea mays by Ueno, Yoshihisa, Yoshizawa-Kumagaye, Kumiko, Emura, Junji, Urabe, Tomoko, Yoshiya, Taku, Furumoto, Tsuyoshi, Izui, Katsura

“…Phosphoenolpyruvate carboxylases (PEPCs), mostly known as the enzymes responsible for the initial CO fixation during C photosynthesis, are regulated by…”
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Development of a sufficiently reactive thioalkylester involving the side-chain thiol of cysteine applicable for kinetically controlled ligation by Tsuda, Shugo, Mochizuki, Masayoshi, Nishio, Hideki, Yoshiya, Taku, Nishiuchi, Yuji

“…ABSTRACT Nα‐Trifluoroacetyl‐Cys‐Leu‐NH2 (TfaC‐Leu‐NH2) was incorporated into thioesters through its side‐chain thiol group to develop a more reactive…”
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Correction to: Tumor vasculature-targeted 10B delivery by an Annexin A1-binding peptide boosts effects of boron neutron capture therapy by Yoneyama, Tohru, Hatakeyama, Shingo, Sutoh Yoneyama, Mihoko, Yoshiya, Taku, Uemura, Tsuyoshi, Ishizu, Takehiro, Suzuki, Minoru, Hachinohe, Shingo, Ishiyama, Shintaro, Nonaka, Motohiro, Fukuda, Michiko N, Ohyama, Chikara

“…An amendment to this paper has been published and can be accessed via the original article…”
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Tumor vasculature-targeted 10B delivery by an Annexin A1-binding peptide boosts effects of boron neutron capture therapy by Yoneyama, Tohru, Hatakeyama, Shingo, Sutoh-Yoneyama, Mihoko, Yoshiya, Taku, Uemura, Tsuyoshi, Ishizu, Takehiro, Suzuki, Minoru, Hachinohe, Shingo, Ishiyama, Shintaro, Nonaka, Motohiro, Fukuda, Michiko N, Ohyama, Chikara

“…Abstract Background p -Boronophenylalanine ( 10 BPA) is a powerful 10 B drug used in current clinical trials of BNCT. For BNCT to be successful, a high (500…”
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