Analgesic effect of caudal epidural ketamine in cattle

This study was performed to clarify the analgesic effect of ketamine injected into the first intercoccygeal (Co1- Co2) epidural space in standing cattle. Five adult cows were randomly received 3 treatments at least 1 week interval: 5, 10 and 20 mL of 5% ketamine. Sedation, analgesia, ataxia and othe...

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Bibliographic Details
Published in:	Journal of veterinary science (Suwŏn-si, Korea) Vol. 4; no. 3; pp. 261 - 264
Main Authors:	Lee, Inhyung, Yoshiuchi, Tomo, Yamagishi, Norio, Oboshi, Kenji, Ayukawa, Yu, Sasaki, Naoki, Yamada, Haruo
Format:	Journal Article
Language:	English
Published:	Korea (South) 대한수의학회 2003
Subjects:	adults adverse effects analgesia Analgesia, Epidural - veterinary analgesic effect Analgesics - administration & dosage Animals ataxia (disorder) Blood Pressure - drug effects Body Temperature - drug effects Cattle - physiology cows Female Heart Rate - drug effects ketamine Ketamine - administration & dosage perineum Respiration - drug effects rumen Rumen - metabolism sedation surgery tail veterinary medicine cattle ketamine caudal epidural anesthesia analgesia
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Summary:	This study was performed to clarify the analgesic effect of ketamine injected into the first intercoccygeal (Co1- Co2) epidural space in standing cattle. Five adult cows were randomly received 3 treatments at least 1 week interval: 5, 10 and 20 mL of 5% ketamine. Sedation, analgesia, ataxia and other effects on cardiopulmonary and rumen functions were assessed before ketamine administration and until 120 min. The analgesia without sedation was shown at tail and perineum about 5 min after all three treatments. The duration of analgesia was significantly increased according to the volume of ketamine (p < 0.01). There was a similar tendency of ataxia with individual variation. There were minimal effects on cardiopulmonary and rumen functions. The present study showed that caudal epidural ketamine administration induced analgesia without sedation in cows, and the duration of analgesia was dose dependent with ataxia. However, the duration of analgesia after 5 and 10 mL ketamine administration is short for common surgical procedures and pain relief of perineum. Further studies are needed to prolong the duration of analgesia without side effects.
Bibliography:	http://www.vetsci.org/paper/list.html?mod=vol&year=2003&book=Journal ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1229-845X 1976-555X
DOI:	10.4142/jvs.2003.4.3.261