Search Results - "Yoshitsugu, Miyazaki"

Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans by Ueno, Keigo, Miyazaki, Yoshitsugu

“…Cryptococcus neoformans and Cryptococcus gattii are pathogenic fungi that infect the human respiratory system and cause life-threatening pulmonary…”
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Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans by Keigo Ueno, Yoshitsugu Miyazaki

“…[ABSTRACT] Cryptococcus neoformans and Cryptococcus gattii are pathogenic fungi that infect the human respiratory system and cause life-threatening pulmonary…”
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Promising whole‐cell vaccines against cryptococcosis by Ueno, Keigo, Tsuge, Soichiro, Shimizu, Kiminori, Miyazaki, Yoshitsugu

“…Cryptococcosis is a mycosis caused by Cryptococcus neoformans and C. gattii species complexes. Although this infection is potentially lethal, no prophylactic…”
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Vaccines and Protective Immune Memory against Cryptococcosis by Ueno, Keigo, Yanagihara, Nao, Shimizu, Kiminori, Miyazaki, Yoshitsugu

“…Cryptococcosis is a potentially lethal disease caused by fungal pathogens including Cryptococcus neoformans and Cryptococcus gattii species complex. These…”
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Expression of Active Staphylococcus aureus Tyrosine Kinases in a Human Cell Line by Fukazawa, Hidesuke, Fukuyama, Mari, Miyazaki, Yoshitsugu

“…Many bacteria encode tyrosine kinases that are structurally unrelated to their eukaryotic counterparts and are termed BY-kinases. Two BY-kinases, CapB1 and…”
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A Fatal Rhizopus Species Infection after Facial Injury in a Patient with Myelodysplastic Syndrome and Diabetes Mellitus by Yanagawa, Youichi, Muramatsu, Ken-ichi, Abe, Masahiro, Miyazaki, Yoshitsugu

“…A 73-year-old woman with myelodysplastic syndrome and diabetes mellitus, chronic renal failure and paroxysmal atrial fibrillation, received a diagnosis of…”
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Clinical Practice Guideline for the Therapeutic Drug Monitoring of Voriconazole in Non-Asian and Asian Adult Patients: Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring by Takesue, Yoshio, Hanai, Yuki, Oda, Kazutaka, Hamada, Yukihiro, Ueda, Takashi, Mayumi, Toshihiko, Matsumoto, Kazuaki, Fujii, Satoshi, Takahashi, Yoshiko, Miyazaki, Yoshitsugu, Kimura, Toshimi

“…Voriconazole, an antifungal drug, is metabolized by a cytochrome P450 isozyme. Increased adverse effects are observed in Asians because of the high rate of…”
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Biofilm-formation capability depends on environmental oxygen concentrations in Candida species by Koshikawa, Takuro, Abe, Masahiro, Nagi, Minoru, Miyazaki, Yoshitsugu, Takemura, Hiromu

“…Although oxygen concentrations inside of the human body vary depending on organs or tissues, few reports describe the relationships between biofilm formation…”
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Potency of gastrointestinal colonization and virulence of Candida auris in a murine endogenous candidiasis by Abe, Masahiro, Katano, Harutaka, Nagi, Minoru, Higashi, Yoshitsugu, Sato, Yuko, Kikuchi, Ken, Hasegawa, Hideki, Miyazaki, Yoshitsugu

“…Candida auris infections have recently emerged worldwide, and this species is highly capable of colonization and is associated with high levels of mortality…”
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Fungal chitin-binding glycoprotein induces Dectin-2-mediated allergic airway inflammation synergistically with chitin by Muraosa, Yasunori, Hino, Yutaro, Takatsuka, Shogo, Watanabe, Akira, Sakaida, Emiko, Saijo, Shinobu, Miyazaki, Yoshitsugu, Yamasaki, Sho, Kamei, Katsuhiko

“…Although chitin in fungal cell walls is associated with allergic airway inflammation, the precise mechanism underlying this association has yet to be…”
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Prevalence of Antifungal Resistance, Genetic Basis of Acquired Azole and Echinocandin Resistance, and Genotyping of Candida krusei Recovered from an International Collection by Khalifa, Hazim O, Hubka, Vit, Watanabe, Akira, Nagi, Minoru, Miyazaki, Yoshitsugu, Yaguchi, Takashi, Kamei, Katsuhiko

“…This study was designed to evaluate the prevalence of antifungal resistance, genetic mechanisms associated with induction of azole and echinocandin resistance…”
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Cryptococcus gattii alters immunostimulatory potential in response to the environment by Ueno, Keigo, Otani, Yoshiko, Yanagihara, Nao, Nakamura, Takumi, Shimizu, Kiminori, Yamagoe, Satoshi, Miyazaki, Yoshitsugu

“…Cryptococcus gattii is a capsular fungal pathogen, which causes life-threatening cryptococcosis in immunocompetent individuals. This emerging pathogen is less…”
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Aspergillus Cell Surface Structural Analysis and Its Applications to Industrial and Medical Use by Miyazawa, Ken, Umeyama, Takashi, Yoshimi, Akira, Abe, Keietsu, Miyazaki, Yoshitsugu

“…The hyphal surface of cells of filamentous fungi is covered with cell wall, which is mainly composed of polysaccharides. Since the cell wall is the first…”
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Real-time monitoring of mycelial growth in liquid culture using hyphal dispersion mutant of Aspergillus fumigatus by Miyazawa, Ken, Umeyama, Takashi, Takatsuka, Shogo, Muraosa, Yasunori, Hoshino, Yasutaka, Yano, Shigekazu, Abe, Keietsu, Miyazaki, Yoshitsugu

“…Hyphal pellet formation by Aspergillus species in liquid cultures is one of the main obstacles to high-throughput anti-Aspergillus reagent screening. We…”
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Detection of significant antiviral drug effects on COVID-19 with reasonable sample sizes in randomized controlled trials: A modeling study by Iwanami, Shoya, Ejima, Keisuke, Kim, Kwang Su, Noshita, Koji, Fujita, Yasuhisa, Miyazaki, Taiga, Kohno, Shigeru, Miyazaki, Yoshitsugu, Morimoto, Shimpei, Nakaoka, Shinji, Koizumi, Yoshiki, Asai, Yusuke, Aihara, Kazuyuki, Watashi, Koichi, Thompson, Robin N, Shibuya, Kenji, Fujiu, Katsuhito, Perelson, Alan S, Iwami, Shingo, Wakita, Takaji

“…Background Development of an effective antiviral drug for Coronavirus Disease 2019 (COVID-19) is a global health priority. Although several candidate drugs…”
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Examination of Cyp51A-Mediated Azole Resistance in Aspergillus lentulus Using CRISPR/Cas9 Genome Editing by Tateno, Madoka, Umeyama, Takashi, Inukai, Tatsuya, Takatsuka, Shogo, Hoshino, Yasutaka, Yamagoe, Satoshi, Murayama, Somay Yamagata, Ishino, Keiko, Miyazaki, Yoshitsugu

“…Aspergillus lentulus was first reported in 2005 as a cryptic species of Aspergillus fumigatus, and since then, its resistance to azole drugs and the high…”
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Artificial Intelligence in the Diagnosis of Invasive Mold Infection: Development of an Automated Histologic Identification System to Distinguish Between Aspergillus and Mucorales by Tochigi, Naobumi, Sadamoto, Sota, Oura, Shinji, Kurose, Yasuko, Miyazaki, Yoshitsugu, Shibuya, Kazutoshi

“…Background: Histopathological identification is usually required since the sensitivity of fungal culture is not sufficient for accurate diagnosis. On the other…”
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α-galactosylceramide-stimulated invariant natural killer T-cells play a protective role in murine vulvovaginal candidiasis by Candida albicans by Abe, Masahiro, Kinjo, Yuki, Sadamoto, Sota, Shinozaki, Minoru, Nagi, Minoru, Shibuya, Kazutoshi, Miyazaki, Yoshitsugu

“…Vulvovaginal candidiasis is a common superficial candidiasis; however, a host's immunological mechanism against vaginal Candida infection remains unknown. In…”
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Quantitative Monitoring of Mycelial Growth of Aspergillus fumigatus in Liquid Culture by Optical Density by Miyazawa, Ken, Umeyama, Takashi, Hoshino, Yasutaka, Abe, Keietsu, Miyazaki, Yoshitsugu

“…Filamentous fungi form multicellular hyphae, which generally form pellets in liquid shake cultures, during the vegetative growth stage. Because of these…”
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Hypertrophic pachymeningitis caused by Schizophyllum sp.: a novel case report by Machida, Masaki, Nakamura, Itaru, Sato, Akihiro, Nakamura, Shigeki, Miyazaki, Yoshitsugu, Watanabe, Hidehiro

“…Background The pathogenic fungus Schizophyllum sp. can cause allergic fungal rhinosinusitis and allergic bronchopulmonary mycosis in humans. Sinus and lung…”
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