Search Results - "Yoshitomo HONDA"

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  1. 1

    Comparison of Osteogenic Potentials of Dental Pulp and Bone Marrow Mesenchymal Stem Cells Using the New Cell Transplantation Platform, CellSaic, in a Rat Congenital Cleft-Jaw Model by Lyu, Jinzhao, Hashimoto, Yoshiya, Honda, Yoshitomo, Matsumoto, Naoyuki

    “…Scaffolds stimulate cell proliferation and differentiation and play major roles in providing growth and nutrition factors in the repair of bone defects. We…”
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    Journal Article
  2. 2

    Integration of Epigallocatechin Gallate in Gelatin Sponges Attenuates Matrix Metalloproteinase-Dependent Degradation and Increases Bone Formation by Huang, Anqi, Honda, Yoshitomo, Li, Peiqi, Tanaka, Tomonari, Baba, Shunsuke

    “…Matrix metalloproteinase (MMP)-2 and MMP-9 are well-known gelatinases that disrupt the extracellular matrix, including gelatin. However, the advantages of…”
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  3. 3

    Osteogenesis of Multipotent Progenitor Cells using the Epigallocatechin Gallate-Modified Gelatin Sponge Scaffold in the Rat Congenital Cleft-Jaw Model by Sasayama, Satoshi, Hara, Tomoya, Tanaka, Tomonari, Honda, Yoshitomo, Baba, Shunsuke

    “…Cost-effective and functionalized scaffolds are in high demand for stem-cell-based regenerative medicine to treat refractory bone defects in craniofacial…”
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  4. 4

    Development of a tooth movement model of root resorption during intrusive orthodontic treatment by ZHOU, Yue, NISHIURA, Aki, MORIKUNI, Hidetoshi, TSUJIBAYASHI, Toru, HONDA, Yoshitomo, MATSUMOTO, Naoyuki

    Published in Dental Materials Journal (25-05-2023)
    “…There is a high risk of external apical root resorption (EARR) following the application of intrusive orthodontic forces to the apical root. However, there is…”
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  5. 5

    Identification of Senescent Cells in Peri-Implantitis and Prevention of Mini-Implant Loss Using Senolytics by Yang, Niuxin, Nakagawa, Masato, Nishiura, Aki, Yamada, Masahiro, Morikuni, Hidetoshi, Honda, Yoshitomo, Matsumoto, Naoyuki

    “…Peri-implantitis is a disease that causes the detachment of orthodontic mini-implants. Recently, stress-induced senescent cells have been reported to be…”
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  6. 6

    Detection of senescent cells in the mucosal healing process on type 2 diabetic rats after tooth extraction for biomaterial development by LUO, Chuyi, NAKAGAWA, Masato, SUMI, Yoichi, MATSUSHIMA, Yasuhiko, UEMURA, Mamoru, HONDA, Yoshitomo, MATSUMOTO, Naoyuki

    Published in Dental Materials Journal (25-05-2024)
    “…The delayed mucosal healing of tooth extraction sockets in diabetes has few known effective treatment strategies, and its underlying mechanism remains unknown…”
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  7. 7

    Enhancement of Bone-Forming Ability on Beta-Tricalcium Phosphate by Modulating Cellular Senescence Mechanisms Using Senolytics by Wang, Xinchen, Honda, Yoshitomo, Zhao, Jianxin, Morikuni, Hidetoshi, Nishiura, Aki, Hashimoto, Yoshiya, Matsumoto, Naoyuki

    “…Various stresses latently induce cellular senescence that occasionally deteriorates the functioning of surrounding tissues. Nevertheless, little is known about…”
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  8. 8

    Exploration of reference genes for the development of a diagnostic kit on vascular aging in human saliva by MIYOSHI, Shinsuke, KAWAMOTO, Akiyo, NINOMIYA, Yuichi, HAMADA, Yoshihiro, SHIMIZU, Hideo, HONDA, Yoshitomo, TAKAHASHI, Kazuya

    Published in Dental Materials Journal (25-03-2024)
    “…Identifying reliable biomarkers in saliva can be a promising approach to developing a rapid diagnostic kit for detecting vascular aging. This study…”
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  9. 9

    Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria by Zhao, Jianxin, Honda, Yoshitomo, Tanaka, Tomonari, Hashimoto, Yoshiya, Matsumoto, Naoyuki

    Published in Materials (23-12-2019)
    “…Lipopolysaccharide (LPS) is a well-known strong inducer of inflammation. However, there is little information regarding how LPS-release behavior affects…”
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  10. 10

    Tailoring Silicon Nitride Surface Chemistry for Facilitating Odontogenic Differentiation of Rat Dental Pulp Cells by Gong, Yanan, Honda, Yoshitomo, Adachi, Tetsuya, Marin, Elia, Yoshikawa, Kazushi, Pezzotti, Giuseppe, Yamamoto, Kazuyo

    “…Silicon nitride (Si N ) can facilitate bone formation; hence, it is used as a biomaterial in orthopedics. Nevertheless, its usability for dentistry is…”
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  11. 11

    Senescence-associated secretory phenotypes in rat-derived dedifferentiated fat cells with replicative senescence by DENG, Wenqi, JO, Jun-ichiro, MORIKUNI, Hidetoshi, SASAYAMA, Satoshi, HASHIMOTO, Yoshiya, MATSUMOTO, Naoyuki, HONDA, Yoshitomo

    Published in Dental Materials Journal (25-05-2023)
    “…Senescence-associated secretory phenotype (SASPs) secreted from senescent cells often cause the deleterious damages to the surrounding tissues. Although…”
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  12. 12

    Localization of senescent cells under cavity preparations in rats and restoration of reparative dentin formation by senolytics by LIU, Haitao, GONG, Yanan, NAKAGAWA, Masato, TANIMOTO, Hiroaki, YOSHIKAWA, Kazushi, HONDA, Yoshitomo, YAMAMOTO, Kazuyo

    Published in Dental Materials Journal (25-05-2023)
    “…Reparative dentin formed by dental cavity preparation (DCP) is frequently used in clinical operations and plays a pivotal role in pulp protection. Recent…”
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  13. 13

    Epigallocatechin Gallate-Modified Gelatins with Different Compositions Alter the Quality of Regenerated Bones by Hara, Eiki, Honda, Yoshitomo, Suzuki, Osamu, Tanaka, Tomonari, Matsumoto, Naoyuki

    “…Bone quality is a significant indicator of the result of bone treatments. However, information regarding the quality of regenerated bones is limited. The study…”
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  14. 14

    Senolytics ameliorate the failure of bone regeneration through the cell senescence-related inflammatory signalling pathway by Wang, Xinchen, Zhou, Yue, Luo, Chuyi, Zhao, Jianxin, Ji, Yuna, Wang, Zheng, Zheng, Pengchao, Li, Dingji, Shi, Yuhan, Nishiura, Aki, Matsumoto, Naoyuki, Honda, Yoshitomo, Xu, Baoshan, Huang, Fang

    Published in Biomedicine & pharmacotherapy (01-06-2024)
    “…Stress-induced premature senescent (SIPS) cells induced by various stresses deteriorate cell functions. Dasatinib and quercetin senolytics (DQ) can alleviate…”
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  15. 15

    Gas Permeability of Mold during Freezing Process Alters the Pore Distribution of Gelatin Sponge and Its Bone-Forming Ability by Han, Xiaoyu, Honda, Yoshitomo, Tanaka, Tomonari, Imura, Kazuki, Hashimoto, Yoshiya, Yoshikawa, Kazushi, Yamamoto, Kazuyo

    Published in Materials (22-10-2020)
    “…Freeze-drying, also known as lyophilization, is widely used in the preparation of porous biomaterials. Nevertheless, limited information is known regarding the…”
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  16. 16

    Application of Green Tea Catechin for Inducing the Osteogenic Differentiation of Human Dedifferentiated Fat Cells in Vitro by Kaida, Koji, Honda, Yoshitomo, Hashimoto, Yoshiya, Tanaka, Masahiro, Baba, Shunsuke

    “…Despite advances in stem cell biology, there are few effective techniques to promote the osteogenic differentiation of human primary dedifferentiated fat…”
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  17. 17

    Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics by Honda, Yoshitomo, Huang, Anqi, Tanaka, Tomonari, Han, Xiaoyu, Gao, Beiyuan, Liu, Haitao, Wang, Xinchen, Zhao, Jianxin, Hashimoto, Yoshiya, Yamamoto, Kazuyo, Matsumoto, Naoyuki, Baba, Shunsuke, Umeda, Makoto

    “…Despite advances in bone regenerative medicine, the relationship between stress-induced premature senescence (SIPS) in cells and bone regeneration remains…”
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  18. 18

    RANKL+ senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics by Zhou, Yue, Nishiura, Aki, Morikuni, Hidetoshi, Deng, Wenqi, Tsujibayashi, Toru, Momota, Yoshihiro, Azetsu, Yuki, Takami, Masamichi, Honda, Yoshitomo, Matsumoto, Naoyuki

    Published in International journal of oral science (30-05-2023)
    “…In dentistry, orthodontic root resorption is a long-lasting issue with no effective treatment strategy, and its mechanisms, especially those related to…”
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  19. 19

    Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control by Honda, Yoshitomo, Ding, Xianting, Mussano, Federico, Wiberg, Akira, Ho, Chih-ming, Nishimura, Ichiro

    Published in Scientific reports (05-12-2013)
    “…Stem cell-based disease modeling presents unique opportunities for mechanistic elucidation and therapeutic targeting. The stable induction of fate-specific…”
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  20. 20