Search Results - "Yoshitomo HONDA"
-
1
Comparison of Osteogenic Potentials of Dental Pulp and Bone Marrow Mesenchymal Stem Cells Using the New Cell Transplantation Platform, CellSaic, in a Rat Congenital Cleft-Jaw Model
Published in International journal of molecular sciences (31-08-2021)“…Scaffolds stimulate cell proliferation and differentiation and play major roles in providing growth and nutrition factors in the repair of bone defects. We…”
Get full text
Journal Article -
2
Integration of Epigallocatechin Gallate in Gelatin Sponges Attenuates Matrix Metalloproteinase-Dependent Degradation and Increases Bone Formation
Published in International journal of molecular sciences (30-11-2019)“…Matrix metalloproteinase (MMP)-2 and MMP-9 are well-known gelatinases that disrupt the extracellular matrix, including gelatin. However, the advantages of…”
Get full text
Journal Article -
3
Osteogenesis of Multipotent Progenitor Cells using the Epigallocatechin Gallate-Modified Gelatin Sponge Scaffold in the Rat Congenital Cleft-Jaw Model
Published in International journal of molecular sciences (29-11-2018)“…Cost-effective and functionalized scaffolds are in high demand for stem-cell-based regenerative medicine to treat refractory bone defects in craniofacial…”
Get full text
Journal Article -
4
Development of a tooth movement model of root resorption during intrusive orthodontic treatment
Published in Dental Materials Journal (25-05-2023)“…There is a high risk of external apical root resorption (EARR) following the application of intrusive orthodontic forces to the apical root. However, there is…”
Get full text
Journal Article -
5
Identification of Senescent Cells in Peri-Implantitis and Prevention of Mini-Implant Loss Using Senolytics
Published in International journal of molecular sciences (28-01-2023)“…Peri-implantitis is a disease that causes the detachment of orthodontic mini-implants. Recently, stress-induced senescent cells have been reported to be…”
Get full text
Journal Article -
6
Detection of senescent cells in the mucosal healing process on type 2 diabetic rats after tooth extraction for biomaterial development
Published in Dental Materials Journal (25-05-2024)“…The delayed mucosal healing of tooth extraction sockets in diabetes has few known effective treatment strategies, and its underlying mechanism remains unknown…”
Get full text
Journal Article -
7
Enhancement of Bone-Forming Ability on Beta-Tricalcium Phosphate by Modulating Cellular Senescence Mechanisms Using Senolytics
Published in International journal of molecular sciences (17-11-2021)“…Various stresses latently induce cellular senescence that occasionally deteriorates the functioning of surrounding tissues. Nevertheless, little is known about…”
Get full text
Journal Article -
8
Exploration of reference genes for the development of a diagnostic kit on vascular aging in human saliva
Published in Dental Materials Journal (25-03-2024)“…Identifying reliable biomarkers in saliva can be a promising approach to developing a rapid diagnostic kit for detecting vascular aging. This study…”
Get full text
Journal Article -
9
Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria
Published in Materials (23-12-2019)“…Lipopolysaccharide (LPS) is a well-known strong inducer of inflammation. However, there is little information regarding how LPS-release behavior affects…”
Get full text
Journal Article -
10
Tailoring Silicon Nitride Surface Chemistry for Facilitating Odontogenic Differentiation of Rat Dental Pulp Cells
Published in International journal of molecular sciences (04-12-2021)“…Silicon nitride (Si N ) can facilitate bone formation; hence, it is used as a biomaterial in orthopedics. Nevertheless, its usability for dentistry is…”
Get full text
Journal Article -
11
Senescence-associated secretory phenotypes in rat-derived dedifferentiated fat cells with replicative senescence
Published in Dental Materials Journal (25-05-2023)“…Senescence-associated secretory phenotype (SASPs) secreted from senescent cells often cause the deleterious damages to the surrounding tissues. Although…”
Get full text
Journal Article -
12
Localization of senescent cells under cavity preparations in rats and restoration of reparative dentin formation by senolytics
Published in Dental Materials Journal (25-05-2023)“…Reparative dentin formed by dental cavity preparation (DCP) is frequently used in clinical operations and plays a pivotal role in pulp protection. Recent…”
Get full text
Journal Article -
13
Epigallocatechin Gallate-Modified Gelatins with Different Compositions Alter the Quality of Regenerated Bones
Published in International journal of molecular sciences (19-10-2018)“…Bone quality is a significant indicator of the result of bone treatments. However, information regarding the quality of regenerated bones is limited. The study…”
Get full text
Journal Article -
14
Senolytics ameliorate the failure of bone regeneration through the cell senescence-related inflammatory signalling pathway
Published in Biomedicine & pharmacotherapy (01-06-2024)“…Stress-induced premature senescent (SIPS) cells induced by various stresses deteriorate cell functions. Dasatinib and quercetin senolytics (DQ) can alleviate…”
Get full text
Journal Article -
15
Gas Permeability of Mold during Freezing Process Alters the Pore Distribution of Gelatin Sponge and Its Bone-Forming Ability
Published in Materials (22-10-2020)“…Freeze-drying, also known as lyophilization, is widely used in the preparation of porous biomaterials. Nevertheless, limited information is known regarding the…”
Get full text
Journal Article -
16
Application of Green Tea Catechin for Inducing the Osteogenic Differentiation of Human Dedifferentiated Fat Cells in Vitro
Published in International journal of molecular sciences (25-11-2015)“…Despite advances in stem cell biology, there are few effective techniques to promote the osteogenic differentiation of human primary dedifferentiated fat…”
Get full text
Journal Article -
17
Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics
Published in International journal of molecular sciences (13-06-2020)“…Despite advances in bone regenerative medicine, the relationship between stress-induced premature senescence (SIPS) in cells and bone regeneration remains…”
Get full text
Journal Article -
18
RANKL+ senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics
Published in International journal of oral science (30-05-2023)“…In dentistry, orthodontic root resorption is a long-lasting issue with no effective treatment strategy, and its mechanisms, especially those related to…”
Get full text
Journal Article -
19
Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control
Published in Scientific reports (05-12-2013)“…Stem cell-based disease modeling presents unique opportunities for mechanistic elucidation and therapeutic targeting. The stable induction of fate-specific…”
Get full text
Journal Article -
20
Epigallocatechin Gallate-Modified Gelatin Sponges Treated by Vacuum Heating as a Novel Scaffold for Bone Tissue Engineering
Published in Molecules (Basel, Switzerland) (11-04-2018)“…Chemical modification of gelatin using epigallocatechin gallate (EGCG) promotes bone formation in vivo. However, further improvements are required to increase…”
Get full text
Journal Article