Search Results - "Yoshitada Notsu"

Effect of humulus lupulus on Gastric Secretion in a Rat Pylorus-Ligated Model by Kurasawa, Takashi, Chikaraishi, Yuichi, Naito, Akira, Toyoda, Yoshihiro, Notsu, Yoshitada

“…In this study, we investigated the pharmacological effect of humulus lupulus (hops) on gastric juice volume and acidity using a rat pylorus-ligated model. In…”
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Novel subtype-selective nonpeptide bradykinin receptor antagonists FR167344 and FR173657 by Aramori, I, Zenkoh, J, Morikawa, N, O'Donnell, N, Asano, M, Nakamura, K, Iwami, M, Kojo, H, Notsu, Y

“…We describe the receptor binding and antagonistic properties of two novel nonpeptide antagonists, FR167344…”
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Nonpeptide mimic of bradykinin with long-acting properties at the bradykinin B2 receptor by Aramori, I, Zenkoh, J, Morikawa, N, Asano, M, Hatori, C, Sawai, H, Kayakiri, H, Satoh, S, Inoue, T, Abe, Y, Sawada, Y, Mizutani, T, Inamura, N, Nakahara, K, Kojo, H, Oku, T, Notsu, Y

“…Kinins, members of a family of peptides released from kininogens by the action of kallikreins, exhibit a variety of biological activities including…”
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Effects of nonsteroidal anti-inflammatory drugs on experimental allergic conjunctivitis in Guinea pigs by Hashimoto, Terumasa, Igarashi, Atsushi, Hoshina, Futoshi, Yamada, Mie, Toyoda, Yoshihiro, Notsu, Yoshitada, Kohno, Shigekatsu

“…The effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on experimental allergic conjunctivitis, induced by ocular challenge with antigen in actively…”
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Change in corneal permeability to timolol after laser in situ keratomileusis and photorefractive keratectomy in rabbit by Hamada, Naoki, Amano, Shiro, Yamagami, Satoru, Araie, Makoto, Oshika, Tetsuro, Wada, Takahiro, Miyai, Hiroko, Notsu, Yoshitada

“…To evaluate the change in corneal permeability to timolol 1 month after laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) in rabbits…”
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Characterization of a novel aldose reductase inhibitor, FR74366, and its effects on diabetic cataract and neuropathy in the rat by Ao, S, Shingu, Y, Kikuchi, C, Takano, Y, Nomura, K, Fujiwara, T, Ohkubo, Y, Notsu, Y, Yamaguchi, I

“…FR74366 (FK366) ([3-(4-bromo-2-fluorobenzyl)-7-chloro-2,4-dioxo-1,2,3,4- tetrahydroquinazolin-1-yl] acetic acid) is a chemically novel aldose reductase (AR)…”
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Effects of FR145237, an Acyl-CoA:cholesterol acyltransferase inhibitor, on diet-induced hypercholesterolemia in diabetic rats by Sakuma, Yuri, Hagihara, Hiroyuki, Nagayoshi, Akira, Ohne, Kazuhiko, Mutoh, Seitaro, Ito, Yoshikuni, Nakahara, Kunio, Notsu, Yoshitada, Okuhara, Masakuni

“…Recent studies have shown that acyl-CoA:cholesterol acyltransferase (ACAT) plays an important role in the initiation of diabetes-associated…”
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Rheological properties of reversible thermo-setting in situ gelling solutions with the methylcellulose-polyethylene glycol-citric acid ternary system by TAKEUCHI, Masanobu, KAGEYAMA, Shinji, SUZUKI, Hidekazu, WADA, Takahiro, NOTSU, Yoshitada, ISHII, Fumiyoshi

“…The composition of vehicle on the reversible sol-gel transition temperature in a ternary system made up of methylcellulose (MC), polyethylene glycol (PEG), and…”
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Alteration in Expression Profiles of a Series of Diabetes-Related Genes in db/db Mice Following Treatment With Thiazolidinediones by Suzuki, Akiko, Yasuno, Toru, Kojo, Hitoshi, Hirosumi, Jiro, Mutoh, Seitaro, Notsu, Yoshitada

“…We studied the effect of pioglitazone on the transcription of 42 genes associated with diabetes to examine the relationship between the antidiabetic action of…”
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Plasma Cholesterol Reducing Effect of FR129169, a Novel Acyl-CoA:Cholesterol Acyltransferase Inhibitor, in the Rat by Sakuma, Yuri, Hagihara, Hiroyuki, Ohne, Kazuhiko, Nagayoshi, Akira, Mutoh, Seitaro, Ito, Yoshikuni, Notsu, Yoshitada, Okuhara, Masakuni

“…FR129169 (FR) (N-(l,2-diphenylethyl)-2-octyloxyphenylacetamide) has been found to inhibit acyl-CoA:cholesterol acyltransferase (ACAT) activities in intestinal…”
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Characterization of the effect of thiazolidinediones on the expression of diabetes-related genes by Suzuki, Akiko, Yasuno, Tohru, Kojo, Hitoshi, Hirosumi, Jiro, Mutoh, Seitaro, Notsu, Yoshitada

“…Thiazolidinediones (TZDs) are a class of insulin sensitizing agents with potent in vivo antidiabetic activities and were recently elucidated to be nuclear…”
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Subtype-selectivity of a vasopressin receptor antagonist, FR161282, for cloned human vasopressin receptors by Zenkoh, Junko, Aramori, Ichiro, Morikawa, Norjyuki, O’Donnell, Nuara, Iwami, Morita, Kojo, Hitoshi, Notsu, Yoshitada

“…Vasopressin (AVP), the neurohypophysial hormone, has some physiological activities including the antidiuretic action, contraction of smooth muscle, stimulation…”
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FR74366, a novel aldose reductase inhibitor. The duration of inhibitory effects of FR74366 on sorbitol accumulation in various tissues of diabetic rats by Ao, Shizuo, Kikuchi, Chie, Notsu, Yoshitada, Yamaguchi, Isamu

“…FR74366 is a novel, potent inhibitor of aldose reductase. In order to examine the duration of activity of FR74366 in vivo, changes in the levels of sorbitol…”
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The Pharmacological Characterization of FK 739, a New Angiotensin II-Receptor Antagonist by Hamada, Kaori, Nakajima, Yoshimitsu, Nirei, Hisataka, Nakajima, Chie, Nagashima, Akira, Sogabe, Keizo, Notsu, Yoshitada, Ono, Takaharu

“…The pharmacological properties of FK 739, a new angiotensin II-receptor antagonist, were examined. FK 739 inhibited the specific binding of [125I]-angiotensin…”
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The expression and pharmacological characterisation of human nNOS and eNOS by Mayako Yamazaki, Akiko Suzuki, Hitoshi Sasaki, Yoshitada Notsu

“…A cDNA encoding a human neuronal nitric oxide synthase (nNOS) was isolated from QUICK-Clone(TM) DNA (CLONTECH Lab., Inc.), and expressed using the…”
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Pharmacological properties of cloned human VIP_1 , VIP_2 and PACAP receptors in stably expressed CHO cells by Shizuo Ao, Ichiro Aramori, Hitoshi Kojo, Hitoshi Sasaki, Yoshitada Notsu

“…Vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are members of the glucagon-secretin family of…”
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Pharmacological characterization of human 5-HT_2C receptors expressed in Chinese hamster ovary cells by Akiko Suzuki, Shizuo Ao, Mayako Yamazaki, Hitoshi Sasaki, Yoshitada Notsu

“…In this study we tried to establish the Chinese hamster ovary (CHO) cells stably expressing human serotonin 5-HT_2C receptors and investigate the…”
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The function and the expression of two Bradykinin (B1, B2) receptor subtypes by Zenkoh, Junko, Aramori, Ichiro, Morikawa, Noriyuki, O'Donnell, Nuala, Nakamura, Kozo, Iwami, Morita, Kojo, Hitoshi, Notsu, Yoshitada

“…The two bradykinin receptors(B1, B2) have seven hydrophobic segments and share a sequence similarity with G protein-coupled receptors. We investigated the…”
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Effects of droloxifene on bone mineral content in rat models by Niikura, Kazuaki, Nakajima, Yoshimitsu, Nishio, Mariko, Nakayama, Osamu, Kojo, Hitoshi, Notsu, Yoshitada, Ono, Takaharu

“…Estrogen is one of few drugs currently is used in the treatment of postmenopausal osteoporosis. However estrogen replacement therapy has the risk of…”
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Subtype- and species-selectivity of the tachykinin antagonist, FK888, for the cloned rat and human tachykinin receptors by Aramori, Ichiro, Morikawa, Noriyuki, Zenkoh, Junko, O'Donnell, Nuala, Iwami, Morita, Kojo, Hitoshi, Notsu, Yoshitada, Okuhara, Masakuni, Ono, Satoshi, Nakanishi, Shigetada

“…We investigated the receptor-binding properties and potencies of FK888, a tachykinin antagonist, for the rat and human tachykinin receptor subtypes (NK_1 ,…”
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