Search Results - "Yoshioka, Hidekatsu"
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Effects of GABA on the expression of type I collagen gene in normal human dermal fibroblasts
Published in Bioscience, biotechnology, and biochemistry (01-02-2017)“…We examined the effects of GABA on type I collagen gene expression in normal human dermal fibroblasts. Real-time PCR analysis indicated GABA increased the…”
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GABA promotes elastin synthesis and elastin fiber formation in normal human dermal fibroblasts (HDFs)
Published in Bioscience, biotechnology, and biochemistry (03-06-2017)“…The multiple physiological effects of γ-aminobutyric acid (GABA) as a functional food component have been recently reported. We previously reported that GABA…”
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Abnormalities in esophageal smooth muscle induced by mutations in collagen XIX
Published in Histochemistry and cell biology (01-02-2022)“…Collagen XIX is a nonfibrillar collagen that localizes in restricted tissues at very low amounts. A previous study on Col19a1 null mice revealed that collagen…”
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A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis
Published in Biochemical journal (15-12-2013)“…Fabry disease is a lysosomal storage disorder in which neutral glycosphingolipids, predominantly Gb3 (globotriaosylceramide), accumulate due to deficient α-Gal…”
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MicroRNA-26 regulates the expression of CTGF after exposure to ionizing radiation
Published in Radiation and environmental biophysics (01-08-2021)“…Radiation-induced fibrosis (RIF) is a serious complication that occurs after irradiation and which is caused by the deposition of extracellular matrix (ECM)…”
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Intragenic copy number variation within human epiplakin 1 (EPPK1) generates variation of molecular size of epiplakin
Published in Journal of dermatological science (01-08-2018)Get full text
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Sp7/Osterix induces the mouse pro-α2(I) collagen gene (Col1a2) expression via the proximal promoter in osteoblastic cells
Published in Biochemical and biophysical research communications (26-09-2014)“…•The extracellular matrix of bone is primary composed of type I collagen.•Sp7/Osterix binds to the proximal promoter of the mouse Col1a2 gene in…”
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Regulation of type I collagen expression by microRNA-29 following ionizing radiation
Published in Radiation and environmental biophysics (01-03-2018)“…Radiation-induced fibrosis (RIF) is thought to involve the excessive accumulation of collagen and other extracellular matrix components; previously, we…”
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Screening of Male Dialysis Patients for Fabry Disease by Plasma Globotriaosylsphingosine
Published in Clinical journal of the American Society of Nephrology (01-04-2013)“…Previous reports of Fabry disease screening in dialysis patients indicate that α-galactosidase A activity alone cannot specifically and reliably identify…”
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Dermatopontin Regulates Fibrin Formation and Its Biological Activity
Published in Journal of investigative dermatology (01-01-2014)“…Dermatopontin (DP) is a small extracellular matrix component in the dermis. Fibrin is a major component of a provisional matrix that is formed just after…”
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p38 MAPK mediates the expression of type I collagen induced by TGF-β2 in human retinal pigment epithelial cells ARPE-19
Published in Investigative ophthalmology & visual science (01-07-2004)Get full text
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Sp1 upregulates the proximal promoter activity of the mouse collagen α1(XI) gene (Col11a1) in chondrocytes
Published in In vitro cellular & developmental biology. Animal (01-02-2016)“…Type XI collagen is a cartilage-specific extracellular matrix, and is important for collagen fibril formation and skeletal morphogenesis. We have previously…”
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Sp7/Osterix up-regulates the mouse pro-α3(V) collagen gene ( Col5a3) during the osteoblast differentiation
Published in Biochemical and biophysical research communications (01-04-2010)“…Type V collagen is a quantitatively minor collagen, but acts as critical regulator of fibril formation in the extracellular matrix. The purpose of this study…”
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Characterization and Expression of Serotonin Transporter Genes in Zebrafish
Published in The Tohoku Journal of Experimental Medicine (2006)“…To understand the development of serotonergic neurons in vertebrates, we used zebrafish as a model system. In this study we cloned two cDNAs (complementary…”
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Epiplakin accelerates the lateral organization of keratin filaments during wound healing
Published in Journal of dermatological science (01-11-2010)“…Abstract Background Epiplakin (EPPK) belongs to the plakin family of cytolinker proteins and, resembling other members of the plakin family such as BPAG1 (an…”
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Nuclear factor Y (NF-Y) regulates the proximal promoter activity of the mouse collagen α1(XI) gene (Col11a1) in chondrocytes
Published in In vitro cellular & developmental biology. Animal (01-04-2014)“…Type XI collagen, a heterotrimer composed of α1(XI), α2(XI), and α3(XI), plays a critical role in cartilage formation and in skeletal morphogenesis. However,…”
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Sp7/Osterix is involved in the up-regulation of the mouse pro-α1(V) collagen gene (Col5a1) in osteoblastic cells
Published in Matrix biology (01-10-2010)“…Sp7/Osterix, a transcription factor whose expression is restricted in osteoblasts, belongs to the Sp family of transcription factor that bind to G/C-rich…”
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Dermatopontin Promotes Epidermal Keratinocyte Adhesion via α3β1 Integrin and a Proteoglycan Receptor
Published in Biochemistry (Easton) (12-01-2010)“…Dermatopontin, an extracellular matrix component initially purified from bovine dermis, promoted cell adhesion of the human epidermal keratinocyte cell line…”
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Preclinical efficacy and safety of 1-deoxygalactonojirimycin in mice for Fabry disease
Published in The Journal of pharmacology and experimental therapeutics (01-03-2009)“…Fabry disease is an inborn error of glycosphingolipid metabolism caused by deficiency of alpha-galactosidase A (alpha-Gal A) activity. It has been shown that…”
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Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils
Published in Environmental health and preventive medicine (01-07-2011)“…The causal agents of gastric cancer could include fungus toxins. Sterigmatocystin (ST), a fungus toxin, is a risk factor of gastric cancer. We investigated the…”
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