Search Results - "Yoshimoto, Rei"

SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns by Fukumura, Kazuhiro, Yoshimoto, Rei, Sperotto, Luca, Kang, Hyun-Seo, Hirose, Tetsuro, Inoue, Kunio, Sattler, Michael, Mayeda, Akila

“…Human pre-mRNA introns vary in size from under fifty to over a million nucleotides. We searched for essential factors involved in the splicing of human short…”
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A Truncated Form of the p27 Cyclin-Dependent Kinase Inhibitor Translated from Pre-mRNA Causes G2-Phase Arrest by Kaida, Daisuke, Satoh, Takayuki, Ishida, Ken, Yoshimoto, Rei, Komori, Kanae

“…Pre-mRNA splicing is an indispensable mechanism for eukaryotic gene expression. Splicing inhibition causes cell cycle arrest at the G 1 and G 2 /M phases, and…”
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Component of splicing factor SF3b plays a key role in translational control of polyribosomes on the endoplasmic reticulum by Ueno, Tomonori, Taga, Yuki, Yoshimoto, Rei, Mayeda, Akila, Hattori, Shunji, Ogawa-Goto, Kiyoko

“…One of the morphological hallmarks of terminally differentiated secretory cells is highly proliferated membrane of the rough endoplasmic reticulum (ER), but…”
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ISG20 and nuclear exosome promote destabilization of nascent transcripts for spliceosomal U snRNAs and U1 variants by Kawamoto, Takahito, Yoshimoto, Rei, Taniguchi, Ichiro, Kitabatake, Makoto, Ohno, Mutsuhito

“…Primary RNA transcripts are processed in a plethora of ways to become mature functional forms. In one example, human spliceosomal U snRNAs are matured at their…”
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Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A by Yoshimoto, Rei, Kaida, Daisuke, Furuno, Masaaki, Burroughs, A Maxwell, Noma, Shohei, Suzuki, Harukazu, Kawamura, Yumi, Hayashizaki, Yoshihide, Mayeda, Akila, Yoshida, Minoru

“…Spliceostatin A (SSA) is a methyl ketal derivative of FR901464, a potent antitumor compound isolated from a culture broth of Pseudomonas sp no. 2663. These…”
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Isolation and characterization of post-splicing lariat–intron complexes by Yoshimoto, Rei, Kataoka, Naoyuki, Okawa, Katsuya, Ohno, Mutsuhito

“…Pre-mRNA splicing occurs in a large complex spliceosome. The steps of both spliceosome assembly and splicing reaction have been extensively analyzed, and many…”
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The production and secretion of tRNA-derived RNA fragments in the corn smut fungus Ustilago maydis by Yoshimoto, Rei, Ishida, Fumiko, Yamaguchi, Miyuki, Tanaka, Shigeyuki

“…The biogenesis of small non-coding RNAs is a molecular event that contributes to cellular functions. The basidiomycete fungus Ustilago maydis is a biotrophic…”
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Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats by Yoshimoto, Rei, Rahimi, Karim, Hansen, Thomas B., Kjems, Jørgen, Mayeda, Akila

“…Circular RNAs (circRNAs) are stable non-coding RNAs with a closed circular structure. One of the best studied circRNAs is ciRS-7 (CDR1as), which acts as a…”
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Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein by Masaki, So, Yoshimoto, Rei, Kaida, Daisuke, Hata, Asuka, Satoh, Takayuki, Ohno, Mutsuhito, Kataoka, Naoyuki

“…In eukaryotes, pre-mRNA splicing is an essential step for gene expression. We have been analyzing post-splicing intron turnover steps in higher eukaryotes…”
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SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression by Matsushita, Kazuyuki, Kajiwara, Toshiko, Tamura, Mai, Satoh, Mamoru, Tanaka, Nobuko, Tomonaga, Takeshi, Matsubara, Hisahiro, Shimada, Hideaki, Yoshimoto, Rei, Ito, Akihiro, Kubo, Shuji, Natsume, Tohru, Levens, David, Yoshida, Minoru, Nomura, Fumio

“…The Far UpStream Element (FUSE)-binding protein-interacting repressor (FIR), a c-myc transcriptional suppressor, is alternatively spliced removing the…”
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Detection of pre-mRNA splicing in vitro by an RNA-templated fluorogenic reaction by Tamura, Yasutsugu, Furukawa, Kazuhiro, Yoshimoto, Rei, Kawai, Yuto, Yoshida, Minoru, Tsuneda, Satoshi, Ito, Yoshihiro, Abe, Hiroshi

“…RNA splicing is an important target for basic research of disease mechanisms and for drug discovery. Here, we report a new method for analysis of the in vitro…”
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MALAT1 long non-coding RNA in cancer by Yoshimoto, Rei, Mayeda, Akila, Yoshida, Minoru, Nakagawa, Shinichi

“…A recent massive parallel sequencing analysis has shown the fact that more than 80% of the human genome is transcribed into RNA. Among many kinds of the…”
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Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor‐1 by Tsuiji, Hitomi, Yoshimoto, Rei, Hasegawa, Yuko, Furuno, Masaaki, Yoshida, Minoru, Nakagawa, Shinichi

“…Gomafu (also referred to as RNCR2/MIAT) was originally identified as a noncoding RNA expressed in a particular set of neurons. Unlike protein‐coding mRNAs, the…”
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SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns by Fukumura, Kazuhiro, Sperotto, Luca, Seuß, Stefanie, Kang, Hyun-Seo, Yoshimoto, Rei, Sattler, Michael, Mayeda, Akila

“…Human pre-mRNA splicing requires the removal of introns with highly variable lengths, from tens to over a million nucleotides. Therefore, mechanisms of intron…”
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Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism by Shimazu, Tadahiro, Yoshimoto, Rei, Kotoshiba, Kaoru, Suzuki, Takehiro, Matoba, Shogo, Hirose, Michiko, Akakabe, Mai, Sohtome, Yoshihiro, Sodeoka, Mikiko, Ogura, Atsuo, Dohmae, Naoshi, Shinkai, Yoichi

“…Histidine (His) residues are methylated in various proteins, but their roles and regulation mechanisms remain unknown. Here, we show that carnosine…”
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A Truncated Form of the p27 Cyclin-Dependent Kinase Inhibitor Translated from Pre-mRNA Causes G 2 -Phase Arrest by Kaida, Daisuke, Satoh, Takayuki, Ishida, Ken, Yoshimoto, Rei, Komori, Kanae

“…Pre-mRNA splicing is an indispensable mechanism for eukaryotic gene expression. Splicing inhibition causes cell cycle arrest at the G and G /M phases, and this…”
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Identification of a novel component C2ORF3 in the lariat–intron complex: lack of C2ORF3 interferes with pre‐mRNA splicing via intron turnover pathway by Yoshimoto, Rei, Okawa, Katsuya, Yoshida, Minoru, Ohno, Mutsuhito, Kataoka, Naoyuki

“…To identify the novel factors involved in the postsplicing intron turnover pathway, we carried out immunoprecipitation with known postsplicing factors, hPrp43…”
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Spliceostatin A interaction with SF3B limits U1 snRNP availability and causes premature cleavage and polyadenylation by Yoshimoto, Rei, Chhipi-Shrestha, Jagat K, Schneider-Poetsch, Tilman, Furuno, Masaaki, Burroughs, A Maxwell, Noma, Shohei, Suzuki, Harukazu, Hayashizaki, Yoshihide, Mayeda, Akila, Nakagawa, Shinichi, Kaida, Daisuke, Iwasaki, Shintaro, Yoshida, Minoru

“…RNA splicing, a highly conserved process in eukaryotic gene expression, is seen as a promising target for anticancer agents. Splicing is associated with other…”
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Fluorescence Detection of Intron Lariat RNA with Reduction-Triggered Fluorescent Probes by Furukawa, Kazuhiro, Abe, Hiroshi, Tamura, Yasutsugu, Yoshimoto, Rei, Yoshida, Minoru, Tsuneda, Satoshi, Ito, Yoshihiro

“…Fluorescence through proximity: Reduction‐triggered fluorescent probes bearing either a fluorescein derivative or triphenylphosphine bind sequence‐specifically…”
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Splicing inhibition induces gene expression through canonical NF-κB pathway and extracellular signal-related kinase activation by Khan, Khalid, Schneider-Poetsch, Tilman, Ishfaq, Muhammad, Ito, Akihiro, Yoshimoto, Rei, Mukaida, Naofumi, Yoshida, Minoru

“…•SSA enhances gene expression through NF-κB and ERK pathway.•Parthenolide and PD98059 inhibit SSA-induced CMV and IL-8 stimulation.•SSA affects IκBα…”
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