Search Results - "Yoshihara, Takashi"
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Haploinsufficiency of RAD51B causes centrosome fragmentation and aneuploidy in human cells
Published in Cancer research (Chicago, Ill.) (15-06-2006)“…The Rad51-like proteins, Rad51B, Rad51C, Rad51D, XRCC2, and XRCC3, have been shown to form two distinct complexes and seem to assist Rad51 in the early stages…”
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DBC2 resistance is achieved by enhancing 26S proteasome-mediated protein degradation
Published in Biochemical and biophysical research communications (31-08-2007)“…Tumor suppressor gene DBC2 stops growth of tumor cells through regulation of CCND1. Interference of CCND1 down-regulation prevented growth arrest caused by…”
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Haploinsufficiency of the Mus81–Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells
Published in Nucleic acids research (2006)“…The Mus81–Eme1 complex is a structure-specific endonuclease that preferentially cleaves nicked Holliday junctions, 3′-flap structures and aberrant replication…”
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Cyclin D1 down-regulation is essential for DBC2’s tumor suppressor function
Published in Biochemical and biophysical research communications (13-07-2007)“…The expression of tumor suppressor gene DBC2 causes certain breast cancer cells to stop growing [M. Hamaguchi, J.L. Meth, C. Von Klitzing, W. Wei, D. Esposito,…”
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XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells
Published in The EMBO journal (11-02-2004)“…XRCC3 was inactivated in human cells by gene targeting. Consistent with its role in homologous recombination, XRCC3−/− cells showed a two‐fold sensitivity to…”
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DBC2 is Essential for Transporting Vesicular Stomatitis Virus Glycoprotein
Published in Journal of molecular biology (01-12-2006)“…DBC2 is a tumor suppressor gene linked to breast and lung cancers. Although DBC2 belongs to the RHO GTPase family, it has a unique structure that contains a…”
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ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction
Published in Nucleic acids research (01-07-2009)“…Rad51C is a central component of two complexes formed by five Rad51 paralogs in vertebrates. These complexes are involved in repairing DNA double-strand breaks…”
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Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G sub(2)/M checkpoints and promotes rereplication in human cells
Published in Nucleic acids research (01-01-2006)“…The Mus81-Eme1 complex is a structure-specific endonuclease that preferentially cleaves nicked Holliday junctions, 3[vprime]-flap structures and aberrant…”
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Localization of Cytosolic NADP-dependent Isocitrate Dehydrogenase in the Peroxisomes of Rat Liver Cells: Biochemical and Immunocytochemical Studies
Published in The journal of histochemistry and cytochemistry (01-09-2001)“…Two types of NADP-dependent isocitrate dehydrogenases (ICDs) have been reported: mitochondrial (ICD1) and cytosolic (ICD2). The C-terminal amino acid sequence…”
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Gasless hand-assisted laparoscopic surgery for colorectal cancer: an option for poor cardiopulmonary reserve
Published in Diseases of the colon & rectum (01-06-2001)“…Gasless hand-assisted surgery, an alternative technique for colorectal cancer, is described. The abdomen is lifted by two metal disks especially designed for…”
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Chronic Subdural Hematoma after External Decompression in Traumatic Intracranial Hematoma: Report of Two Cases
Published in Neurologia medico-chirurgica (1987)“…Two cases of chronic subdural hematoma after craniotomy, removal of the hematoma, dural plasty using lyophilized human cadaver dura mater, and external…”
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急性頭蓋内血腫に対する外減圧術後に発生した慢性硬膜下血腫
Published in Neurologia medico-chirurgica (1987)Get full text
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