Search Results - "Yoshida, Eiko"
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Involvement of adenosine A2B receptor in radiation-induced translocation of epidermal growth factor receptor and DNA damage response leading to radioresistance in human lung cancer cells
Published in Biochimica et biophysica acta. General subjects (01-01-2020)“…Adenosine receptors are involved in tumor growth, progression, and response to therapy. Among them, A2B receptor is highly expressed in various tumors…”
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Multilevel factor analysis of flipped classroom in dental education: A 3-year randomized controlled trial
Published in PloS one (10-09-2021)“…Purpose Previous studies have rarely attempted to test the confounding factors that may affect learning outcomes of the flipped classroom. The purpose of this…”
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The association between mucosal pain and subjective masticatory function in patients with partial removable dental prostheses
Published in Journal of oral rehabilitation (01-12-2019)“…Background Improvement of masticatory function is critical in prosthetic treatment. Multiple factors are related to patients' perception of chewing ability in…”
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Effects of Canagliflozin on Hepatic Steatosis, Visceral Fat and Skeletal Muscle among Patients with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease
Published in Internal Medicine (01-11-2021)“…Objective We assessed the effect of canagliflozin, an sodium-glucose co-transporter type-2 inhibitor, on hepatic steatosis using three imaging modalities:…”
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A new masticatory performance scale to integrate food biting, comminution and mixing ability in removable partial denture wearers
Published in Journal of oral rehabilitation (01-07-2021)“…Background The existing masticatory performance (MP) tests cannot comprehensively evaluate objective masticatory function. Objectives We aimed to examine the…”
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Responsiveness of methods to evaluate chewing ability after removable partial denture treatments
Published in Journal of oral rehabilitation (01-04-2021)“…Background The ability of an instrument to detect a clinically important change in patient‐reported outcomes following prosthetic treatment is critical for its…”
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Biglycan Intensifies ALK5–Smad2/3 Signaling by TGF‐β1 and Downregulates Syndecan‐4 in Cultured Vascular Endothelial Cells
Published in Journal of cellular biochemistry (01-05-2017)“…ABSTRACT Proteoglycans are macromolecules that consist of a core protein and one or more glycosaminoglycan side chains. A small leucine‐rich dermatan sulfate…”
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Transforming Growth Factor‐β1 Modulates the Expression of Syndecan‐4 in Cultured Vascular Endothelial Cells in a Biphasic Manner
Published in Journal of cellular biochemistry (01-08-2017)“…ABSTRACT Proteoglycans are macromolecules that consist of a core protein and one or more glycosaminoglycan side chains. Previously, we reported that…”
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Hypoalgesia and recovery in methylmercury-exposed rats
Published in Journal of toxicological sciences (01-01-2021)“…Methylmercury (MeHg), the causal substrate in Minamata disease, can lead to severe and chronic neurological disorders. The main symptom of Minamata disease is…”
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Glutathione Adduct of Methylmercury Activates the Keap1–Nrf2 Pathway in SH-SY5Y Cells
Published in Chemical research in toxicology (20-10-2014)“…Methylmercury (MeHg) reacts readily with GSH, leading to the formation of a MeHg–SG adduct that is excreted into extracellular space through…”
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Nuclear factor erythroid 2-related factor 2 (NRF2) is a negative regulator of tissue plasminogen activator synthesis in cultured human vascular endothelial EA.hy926 cells
Published in Journal of toxicological sciences (01-01-2020)“…Blood coagulation and the fibrinolytic system contribute to vascular lesions. Fibrinolysis in normal circulating blood strongly depends on the balance between…”
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Comparative study of susceptibility to methylmercury cytotoxicity in cell types composing rat peripheral nerves: a higher susceptibility of dorsal root ganglion neurons
Published in Journal of toxicological sciences (01-01-2024)“…Methylmercury is an environmental polluting organometallic compound that exhibits neurotoxicity, as observed in Minamata disease patients. Methylmercury…”
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Arsenite Inhibits Tissue-Type Plasminogen Activator Synthesis through NRF2 Activation in Cultured Human Vascular Endothelial EA.hy926 Cells
Published in International journal of molecular sciences (13-01-2021)“…Chronic arsenic exposure is known to be related to the progression of atherosclerosis. However, the pathogenic mechanisms of arsenic-induced atherosclerosis…”
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Gene expression profiles in the dorsal root ganglia of methylmercury-exposed rats
Published in Journal of toxicological sciences (2019)“…Methylmercury (MeHg) exposure is known to induce neurodegeneration in both the central nervous system (CNS) and peripheral nervous system (PNS). Molecular…”
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Induction of metallothionein isoforms by copper diethyldithiocarbamate in cultured vascular endothelial cells
Published in Journal of toxicological sciences (01-04-2016)“…Metallothionein (MT) plays a central role in cellular defense against heavy metals and oxidative stress. Since the induction of MT requires the activation of…”
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Possible mechanisms underlying transcriptional induction of metallothionein isoforms by tris(pentafluorophenyl)stibane, tris(pentafluorophenyl)arsane, and tris(pentafluorophenyl)phosphane in cultured bovine aortic endothelial cells
Published in Journal of toxicological sciences (01-01-2019)“…Metallothionein (MT) is a low-molecular-weight, cysteine-rich, and metal-binding protein that protects cells from the cytotoxic effects of heavy metals and…”
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Pre‐treatment impairment of oral health‐related quality of life is associated with variations in minimal clinically important differences among patients with removable partial denture treatment
Published in Journal of oral rehabilitation (01-07-2020)“…Background The minimal clinically important differences (MID) of the Oral Health‐related Quality of Life (OHRQoL) are the benchmark to meaningfully interpret…”
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Detoxification of Methylmercury by Hydrogen Sulfide-Producing Enzyme in Mammalian Cells
Published in Chemical research in toxicology (17-10-2011)“…Methylmercury (MeHg) covalently modifies cellular proteins through their SH groups, resulting in cytotoxicity. We report that cystathionine β-synthase (CBS),…”
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Methylmercury induces hyaluronan synthesis in cultured human brain microvascular endothelial cells and pericytes via different mechanisms
Published in Journal of toxicological sciences (2017)“…In a cerebrum damaged by methylmercury, where neuropathological lesions tend to localize along deep sulci and fissures, edematous changes in white matter have…”
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Methylmercury-induced neural degeneration in rat dorsal root ganglion is associated with the accumulation of microglia/macrophages and the proliferation of Schwann cells
Published in Journal of toxicological sciences (01-01-2019)“…Exposure to organic mercury, especially methylmercury (MeHg), causes Minamata disease, a severe chronic neurological disorder. Minamata disease predominantly…”
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