Search Results - "York, Michael"

Skeletal muscle adaptations following eccentric contractions are not mediated by keratin 18 by Ganjayi, Muni Swamy, Frank, Samuel W, Krauss, Thomas A, York, Michael L, Bloch, Robert J, Baumann, Cory W

“…The molecular mechanisms that drive muscle adaptations after eccentric exercise training are multifaceted and likely impacted by age. Previous studies have…”
Get full text

Poly(I:C) Drives Type I IFN- and TGFβ-Mediated Inflammation and Dermal Fibrosis Simulating Altered Gene Expression in Systemic Sclerosis by Farina, Giuseppina A., York, Michael R., Di Marzio, Michael, Collins, Cindy A., Meller, Stephan, Homey, Bernhard, Rifkin, Ian R., Marshak-Rothstein, Ann, Radstake, Timothy R.D.J., Lafyatis, Robert

“…Immune activation of fibrosis likely has a crucial role in the pathogenesis of systemic sclerosis (SSc). The aim of this study was to better understand the…”
Get full text

Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcγRIIA-Dependent but TLR-Independent Response by Bonegio, Ramon G, Lin, Jessica D, Beaudette-Zlatanova, Britte, York, Michael R, Menn-Josephy, Hanni, Yasuda, Kei

“…Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against nucleic acids and nucleoproteins…”
Get full text

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes by Farina, Antonella, Peruzzi, Giovanna, Lacconi, Valentina, Lenna, Stefania, Quarta, Silvia, Rosato, Edoardo, Vestri, Anna Rita, York, Michael, Dreyfus, David H, Faggioni, Alberto, Morrone, Stefania, Trojanowska, Maria, Farina, G Alessandra

“…Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon…”
Get full text

Innate Immune Modulation Induced by EBV Lytic Infection Promotes Endothelial Cell Inflammation and Vascular Injury in Scleroderma by Farina, Antonella, Rosato, Edoardo, York, Michael, Gewurz, Benjamin E, Trojanowska, Maria, Farina, Giuseppina Alessandra

“…Microvascular injury is considered an initial event in the pathogenesis of scleroderma and endothelial cells are suspected of being the target of the…”
Get full text

Epstein–Barr Virus Infection Induces Aberrant TLR Activation Pathway and Fibroblast–Myofibroblast Conversion in Scleroderma by Farina, Antonella, Cirone, Mara, York, Michael, Lenna, Stefania, Padilla, Cristina, Mclaughlin, Sarah, Faggioni, Alberto, Lafyatis, Robert, Trojanowska, Maria, Farina, Giuseppina A.

“…Scleroderma (SSc) is a complex and heterogeneous connective tissue disease mainly characterized by autoimmunity, vascular damage, and fibrosis that mostly…”
Get full text

Community-engaged randomised controlled trial to disseminate COVID-19 vaccine-related information and increase uptake among Black individuals in two US cities with rheumatic conditions by Sirek, Greta, Erickson, Daniel, Muhammad, Lutfiyya N, Losina, Elena, Chandler, Mia T, Son, Mary Beth, Crespo-Bosque, Monica, York, Michael, Jean-Jacques, Muriel, Milaeger, Holly, Pillai, Neil, Roberson, Tonya, Chung, Anh, Shramuk, Maxwell, Osaghae, Eseosa, Williams, Jessica, Ojikutu, Bisola O, Dhand, Amar, Ramsey-Goldman, Rosalind, Feldman, Candace H

“…IntroductionInequities in COVID-19 infection and vaccine uptake among historically marginalised racial and ethnic groups in the USA persist. Individuals with…”
Get full text

Novel insights on the role of the innate immune system in systemic sclerosis by York, Michael R

“…Over the last several years the involvement of the innate immune system in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE)…”
Get more information

Recent diuretic use and the risk of recurrent gout attacks: the online case-crossover gout study by Hunter, David J, York, Michael, Chaisson, Christine E, Woods, Ryan, Niu, Jingbo, Zhang, Yuqing

“…OBJECTIVE: To assess several putative risk factors, including thiazide and loop diuretics use, thought to trigger recurrent gout attacks. METHODS: We conducted…”
Get full text

A woman with severe lupus nephritis and difficult to control diabetes mellitus by Buhaescu, Irina, Rhee, Soo, York, Michael R., McDonnell, Marie, Merkel, Peter A.

Get full text

Determination of skin irritation potential in the human 4-h patch test by Basketter, David A., York, Michael, McFadden, John P., Robinson, Michael K.

“…Recently adopted legislation in Europe has increased the focus that must be placed on the development of in vitro alternatives to the traditional toxicology…”
Get full text

A critical review of the assessment of eye irritation potential using the draize rabbit eye test by York, Michael, Steiling, Winfried

“…Traditionally, the eye irritation potential of substances and products has been assessed using the Draize eye test. While this procedure has been criticized in…”
Get full text

Comment on Perceptual Defense in Anxiety Disorders by York, Michael W.

“…This paper is intended to lend support to the 2003 findings of Poloni, Riquier, Zimmermann, and Borgeat. Further, some extensions of these and other findings…”
Get full text

Violence against Indonesian Migrant Workers - A Causal Analysis by Johan Kusuma, Ardli, Ryan York, Michael, Hari Wibowo, Rizki

“…Violence and abuse against Indonesian unskilled labourers and migrant workers has become prolific and is a serious breach of human rights. This research will…”
Get full text

A macrophage marker, siglec‐1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type i interferons and toll‐like receptor agonists by York, Michael R., Nagai, Taro, Mangini, Alyson J., Lemaire, Raphaël, van Seventer, Jean Maguire, Lafyatis, Robert

“…Objective Microarray analyses of peripheral blood leukocytes have shown that patients with systemic lupus erythematosus express increased levels of type I…”
Get full text

Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients by Rice, Lisa M, Padilla, Cristina M, McLaughlin, Sarah R, Mathes, Allison, Ziemek, Jessica, Goummih, Salma, Nakerakanti, Sashidhar, York, Michael, Farina, Giuseppina, Whitfield, Michael L, Spiera, Robert F, Christmann, Romy B, Gordon, Jessica K, Weinberg, Janice, Simms, Robert W, Lafyatis, Robert

“…TGF-β has potent profibrotic activity in vitro and has long been implicated in systemic sclerosis (SSc), as expression of TGF-β-regulated genes is increased in…”
Get full text

ASEAN’S AMBIGUOUS ROLE IN RESOLVING SOUTH CHINA SEA DISPUTES by York, Michael

Get full text

The Relationship Between Renal Flares and Continuity of Medical Care in Patients with Lupus Nephritis: PO1599 by Alsharhan, Loulwa, Schmidt, Insa M., Bonegio, Ramon, York, Michael R., Lam, Christina, Crespo-Bosque, Monica, Waikar, Sushrut S., Menn-Josephy, Hanni

Get full text

Innate immunity and inflammation in systemic sclerosis by Lafyatis, Robert, York, Michael

“…PURPOSE OF REVIEWRecent advances in our understanding of innate immunity and inflammation have direct bearing on how we understand autoimmunity, fibrosis and…”
Get full text

dsRNA activation of endothelin-1 and markers of vascular activation in endothelial cells and fibroblasts by Farina, Giuseppina, York, Michael, Collins, Cindy, Lafyatis, Robert

“…In patients with systemic sclerosis (SSc), the relationship between innate immune activation, represented by increased expression of interferon (IFN)-regulated…”
Get more information