Search Results - "Yoon, Tae Young"

Direct evaluation of self-quenching behavior of fluorophores at high concentrations using an evanescent field by Bae, Wooli, Yoon, Tae-Young, Jeong, Cherlhyun

“…The quantum yield of a fluorophore is reduced when two or more identical fluorophores are in close proximity to each other. The study of protein folding or…”
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Reconstruction of LPS Transfer Cascade Reveals Structural Determinants within LBP, CD14, and TLR4-MD2 for Efficient LPS Recognition and Transfer by Ryu, Je-Kyung, Kim, Soo Jin, Rah, Sang-Hyun, Kang, Ji In, Jung, Hi Eun, Lee, Dongsun, Lee, Heung Kyu, Lee, Jie-Oh, Park, Beom Seok, Yoon, Tae-Young, Kim, Ho Min

“…Lipopolysaccharide (LPS), the major component of the outer membrane of Gram-negative bacteria, binds Toll-like receptor 4 (TLR4)-MD2 complex and activates…”
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Emerging Biophysics Tools for Biologists by Yoon, Tae-Young

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Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover by Ryu, Je-Kyung, Min, Duyoung, Rah, Sang-Hyun, Kim, Soo Jin, Park, Yongsoo, Kim, Haesoo, Hyeon, Changbong, Kim, Ho Min, Jahn, Reinhard, Yoon, Tae-Young

“…During intracellular membrane trafficking, N-ethylmaleimide-sensitive factor (NSF) and alpha-soluble NSF attachment protein (α-SNAP) disassemble the soluble…”
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Review: Progresses in understanding N‐ethylmaleimide sensitive factor (NSF) mediated disassembly of SNARE complexes by Ryu, Je-Kyung, Jahn, Reinhard, Yoon, Tae‐Young

“…ABSTRACT N‐ethylmaleimide sensitive factor (NSF) is a key protein of intracellular membrane traffic. NSF is a highly conserved protein belonging to the ATPases…”
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Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension by Shon, Min Ju, Kim, Haesoo, Yoon, Tae-Young

“…Neuronal soluble N -ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) catalyze synaptic vesicle fusion with presynaptic membranes through…”
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The New Kid on the Block: Mass Photometry by Graciani, Guillaume, Yoon, Tae-Young

“…Mass photometry is a technique that is less than five years old, yet it has already experienced widespread laboratory adoption, is sold commercially, and has…”
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Structural basis of neuropeptide Y signaling through Y1 receptor by Park, Chaehee, Kim, Jinuk, Ko, Seung-Bum, Choi, Yeol Kyo, Jeong, Hyeongseop, Woo, Hyeonuk, Kang, Hyunook, Bang, Injin, Kim, Sang Ah, Yoon, Tae-Young, Seok, Chaok, Im, Wonpil, Choi, Hee-Jung

“…Neuropeptide Y (NPY) is highly abundant in the brain and involved in various physiological processes related to food intake and anxiety, as well as human…”
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Watching helical membrane proteins fold reveals a common N-to-C-terminal folding pathway by Choi, Hyun-Kyu, Min, Duyoung, Kang, Hyunook, Shon, Min Ju, Rah, Sang-Hyun, Kim, Hak Chan, Jeong, Hawoong, Choi, Hee-Jung, Bowie, James U, Yoon, Tae-Young

“…To understand membrane protein biogenesis, we need to explore folding within a bilayer context. Here, we describe a single-molecule force microscopy technique…”
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Extreme parsimony in ATP consumption by 20S complexes in the global disassembly of single SNARE complexes by Kim, Changwon, Shon, Min Ju, Kim, Sung Hyun, Eun, Gee Sung, Ryu, Je-Kyung, Hyeon, Changbong, Jahn, Reinhard, Yoon, Tae-Young

“…Fueled by ATP hydrolysis in N -ethylmaleimide sensitive factor (NSF), the 20S complex disassembles rigid SNARE (soluble NSF attachment protein receptor)…”
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Shedding light on complexity of protein–protein interactions in cancer by Yoon, Tae-Young, Lee, Hong-Won

“…Most cell signaling and surveillance circuits are physically maintained through a dense network of protein–protein interactions (PPIs). Genetic mutations,…”
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Single‐Molecule Co‐Immunoprecipitation Reveals Functional Inheritance of EGFRs in Extracellular Vesicles by Sung, Mi Sook, Jung, Jik‐Han, Jeong, Cherlhyun, Yoon, Tae‐Young, Park, Ji‐Ho

“…Cancer cells actively release extracellular vesicles (EVs) as important carriers of cellular information to tumor microenvironments. Although the composition…”
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MutS switches between two fundamentally distinct clamps during mismatch repair by Ban, Changill, Fishel, Richard, Lee, Jong-Bong, Jeong, Cherlhyun, Cho, Won-Ki, Song, Kyung-Mi, Cook, Christopher, Yoon, Tae-Young

“…MutS scans DNA for mismatches; once a lesion is recognized, MutS initiates a cascade of events that ultimately results in mismatch excision and repair. Now the…”
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Multiple Intermediates in SNARE-Induced Membrane Fusion by Yoon, Tae-Young, Okumus, Burak, Zhang, Fan, Shin, Yeon-Kyun, Ha, Taekjip

“…Membrane fusion in eukaryotic cells is thought to be mediated by a highly conserved family of proteins called SNAREs (soluble N-ethyl maleimide…”
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Phosphorylated EGFR Dimers Are Not Sufficient to Activate Ras by Liang, Samantha I., van Lengerich, Bettina, Eichel, Kelsie, Cha, Minkwon, Patterson, David M., Yoon, Tae-Young, von Zastrow, Mark, Jura, Natalia, Gartner, Zev J.

“…Growth factor binding to EGFR drives conformational changes that promote homodimerization and transphosphorylation, followed by adaptor recruitment,…”
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Single-molecule functional anatomy of endogenous HER2-HER3 heterodimers by Choi, Byoungsan, Cha, Minkwon, Eun, Gee Sung, Lee, Dae Hee, Lee, Seul, Ehsan, Muhammad, Chae, Pil Seok, Heo, Won Do, Park, YongKeun, Yoon, Tae-Young

“…Human epidermal growth factor receptors (HERs) are the primary targets of many directed cancer therapies. However, the reason a specific dimer of HERs…”
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Evolutionary balance between foldability and functionality of a glucose transporter by Choi, Hyun-Kyu, Kang, Hyunook, Lee, Chanwoo, Kim, Hyun Gyu, Phillips, Ben P., Park, Soohyung, Tumescheit, Charlotte, Kim, Sang Ah, Lee, Hansol, Roh, Soung-Hun, Hong, Heedeok, Steinegger, Martin, Im, Wonpil, Miller, Elizabeth A., Choi, Hee-Jung, Yoon, Tae-Young

“…Despite advances in resolving the structures of multi-pass membrane proteins, little is known about the native folding pathways of these complex structures…”
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Low-power nano-optical vortex trapping via plasmonic diabolo nanoantennas by Kang, Ju-Hyung, Kim, Kipom, Ee, Ho-Seok, Lee, Yong-Hee, Yoon, Tae-Young, Seo, Min-Kyo, Park, Hong-Gyu

“…Optical vortex trapping can allow the capture and manipulation of micro- and nanometre-sized objects such as damageable biological particles or particles with…”
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A single vesicle-vesicle fusion assay for in vitro studies of SNAREs and accessory proteins by Diao, Jiajie, Ishitsuka, Yuji, Lee, Hanki, Joo, Chirlmin, Su, Zengliu, Syed, Salman, Shin, Yeon-Kyun, Yoon, Tae-Young, Ha, Taekjip

“…SNARE (soluble N -ethylmaleimide-sensitive factor attachment protein receptor) proteins are a highly regulated class of membrane proteins that drive the…”
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Synaptic vesicle fusion: today and beyond by Brose, Nils, Brunger, Axel, Cafiso, David, Chapman, Edwin R., Diao, Jiajie, Hughson, Frederick M., Jackson, Meyer B., Jahn, Reinhard, Lindau, Manfred, Ma, Cong, Rizo, Josep, Shin, Yeon-Kyun, Söllner, Thomas H., Tamm, Lukas, Yoon, Tae-Young, Zhang, Yongli

“…Researchers working on synaptic vesicle fusion and neurotransmitter release share their views on the most interesting developments in their field and the…”
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