Search Results - "Yoon, Seo Yeon"
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Spinal astrocyte gap junctions contribute to oxaliplatin-induced mechanical hypersensitivity
Published in The journal of pain (01-02-2013)“…Spinal glial cells contribute to the development of many types of inflammatory and neuropathic pain. Here the contribution of spinal astrocytes and astrocyte…”
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Induction of monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR2 in primary sensory neurons contributes to paclitaxel-induced peripheral neuropathy
Published in The journal of pain (01-10-2013)“…The use of paclitaxel (Taxol), a microtubule stabilizer, for cancer treatment is often limited by its associated peripheral neuropathy (chemotherapy-induced…”
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Differential Development of Facial and Hind Paw Allodynia in a Nitroglycerin-Induced Mouse Model of Chronic Migraine: Role of Capsaicin Sensitive Primary Afferents
Published in Biological & pharmaceutical bulletin (01-02-2018)“…Despite the relatively high prevalence of migraine or headache, the pathophysiological mechanisms triggering headache-associated peripheral hypersensitivities,…”
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The Peripheral Role of CCL2 in the Anti-Nociceptive Effect of Sigma-1 Receptor Antagonist BD1047 on Inflammatory Hyperalgesia in Rats
Published in International journal of molecular sciences (29-10-2021)“…Our recent study demonstrated that the CC-chemokine ligand 2 (CCL2) present in primary afferent fibers (PAFs) plays an important role in the…”
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5
Clonidine, an alpha‐2 adrenoceptor agonist relieves mechanical allodynia in oxaliplatin‐induced neuropathic mice; potentiation by spinal p38 MAPK inhibition without motor dysfunction and hypotension
Published in International journal of cancer (15-05-2016)“…Cancer chemotherapy with platinum‐based antineoplastic agents including oxaliplatin frequently results in a debilitating and painful peripheral neuropathy. We…”
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Sigma-1 Receptor Antagonist, BD1047 Reduces Nociceptive Responses and Phosphorylation of p38 MAPK in Mice Orofacial Formalin Model
Published in Biological & pharmaceutical bulletin (01-01-2014)“…Sigma-1 receptors (Sig-1Rs) play a role in different types of pain and in central sensitization mechanism in spinal cord. However, it is currently unexplored…”
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Differential involvement of ipsilateral and contralateral spinal cord astrocyte D‐serine in carrageenan‐induced mirror‐image pain: role of σ1 receptors and astrocyte gap junctions
Published in British journal of pharmacology (01-02-2018)“…Background and Purpose Although we have recently demonstrated that spinal astrocyte gap junctions mediate the development of mirror‐image pain (MIP), it is…”
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Astrocyte D-serine modulates the activation of neuronal NOS leading to the development of mechanical allodynia in peripheral neuropathy
Published in Molecular pain (01-01-2019)“…Spinal D-serine plays an important role in nociception via an increase in phosphorylation of the N-Methyl-D-aspartate (NMDA) receptor GluN1 subunit (pGluN1)…”
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Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice
Published in Neuropharmacology (01-12-2016)“…We have previously shown using a spinal cord injury (SCI) model that gap junctions contribute to the early spread of astrocyte activation in the lumbar spinal…”
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10
Hepatocyte-specific Prominin-1 protects against liver injury-induced fibrosis by stabilizing SMAD7
Published in Experimental & molecular medicine (01-08-2022)“…Prominin-1 (PROM1), also known as CD133, is expressed in hepatic progenitor cells (HPCs) and cholangiocytes of the fibrotic liver. In this study, we show that…”
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Spinal neuronal NOS activation mediates sigma‐1 receptor‐induced mechanical and thermal hypersensitivity in mice: involvement of PKC‐dependent GluN1 phosphorylation
Published in British journal of pharmacology (01-08-2011)“…BACKGROUND AND PURPOSE We recently demonstrated that activation of the spinal sigma‐1 receptor induces mechanical and thermal hypersensitivity via…”
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12
Different Involvement of ASIC and TRPA1 in Facial and Hindpaw Allodynia in Nitroglycerin-Induced Peripheral Hypersensitivities in Mice
Published in Life (Basel, Switzerland) (23-08-2022)“…The pathophysiological mechanism underlying migraine-associated peripheral hypersensitivity remains unclear. Acid-sensing ion channels (ASICs) and transient…”
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GV16 acupoint stimulation with bee venom reduces peripheral hypersensitivity via activation of α2 adrenoceptors in a nitroglycerin-induced migraine mouse model
Published in Integrative medicine research (01-12-2023)“…Peripheral hypersensitivities develop in the face and hindpaws of mice with nitroglycerin (NTG)-induced migraine. We evaluated whether diluted bee venom (DBV)…”
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Intrathecal RGS4 Inhibitor, CCG50014, Reduces Nociceptive Responses and Enhances Opioid-Mediated Analgesic Effects in the Mouse Formalin Test
Published in Anesthesia and analgesia (01-03-2015)“…The regulator of G-protein signaling protein type 4 (RGS4) accelerates the guanosine triphosphatase activity of G(αi) and G(αo), resulting in the inactivation…”
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Clonidine Reduces Nociceptive Responses in Mouse Orofacial Formalin Model: Potentiation by Sigma-1 Receptor Antagonist BD1047 without Impaired Motor Coordination
Published in Biological & pharmaceutical bulletin (2015)“…Although the administration of clonidine, an alpha-2 adrenoceptor agonist, significantly attenuates nociception and hyperalgesia in several pain models,…”
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Intrathecal Injection of the ς1Receptor Antagonist BD1047 Blocks Both Mechanical Allodynia and Increases in Spinal NR1 Expression during the Induction Phase of Rodent Neuropathic Pain
Published in Anesthesiology (Philadelphia) (01-11-2008)“…Background Selective blockade of spinal sigma(1) receptors (Sig-1R) suppresses nociceptive behaviors in the mouse formalin test. The current study was designed…”
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Spinal sigma-1 receptor activation increases the production of d-serine in astrocytes which contributes to the development of mechanical allodynia in a mouse model of neuropathic pain
Published in Pharmacological research (01-10-2015)“…[Display omitted] DAAO, d-amino acid oxidase; i.t., intrathecal; LSOS, l-serine O-sulfate potassium salt; NMDA R, N-methyl-d-aspartate receptor; Sig-1R,…”
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18
Blockade of peripheral P2Y1 receptors prevents the induction of thermal hyperalgesia via modulation of TRPV1 expression in carrageenan-induced inflammatory pain rats: Involvement of p38 MAPK phosphorylation in DRGs
Published in Neuropharmacology (01-04-2014)“…Although previous reports have suggested that P2Y1 receptors (P2Y1Rs) are involved in cutaneous nociceptive signaling, it remains unclear how P2Y1Rs contribute…”
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Diluted Bee Venom Injection Reduces Ipsilateral Mechanical Allodynia in Oxaliplatin-Induced Neuropathic Mice
Published in Biological & pharmaceutical bulletin (01-11-2013)“…Oxaliplatin, which is used as one of anti-cancer drugs, commonly induces peripheral neuropathic pain. We have previously reported that an injection of diluted…”
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Spinal sigma-1 receptors activate NADPH oxidase 2 leading to the induction of pain hypersensitivity in mice and mechanical allodynia in neuropathic rats
Published in Pharmacological research (01-08-2013)“…We have recently demonstrated that spinal sigma-1 receptors (Sig-1Rs) mediate pain hypersensitivity in mice and neuropathic pain in rats. In this study, we…”
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