Search Results - "Yoon, Myung Ha"

Synthesis and Structure-Activity Relationship Studies of Benzimidazole-4,7-dione-Based P2X3 Receptor Antagonists as Novel Anti-Nociceptive Agents by Bae, Jinsu, Kim, Yeo-Ok, Han, Xuehao, Yoon, Myung-Ha, Kim, Woong-Mo, Kim, Yong-Chul

“…P2X3 receptors (P2X3R) are ATP-gated ion channels predominantly expressed in C- and Aδ-fiber primary afferent neurons and have been introduced as a novel…”
Get full text

Discovery of pyrazole‐1‐carboxamide derivatives as novel Gi‐biased μ‐opioid receptor agonists by Jung, Jae‐Hoon, Jang, In Hee, Kim, Yeo Ok, Kim, Sunhong, Yoon, Myung Ha, Kim, Yong‐Chul

“…μ‐Opioid receptor (MOR) Gi‐biased agonists with no recruitment of β‐arrestin were introduced as a new analgesic strategy to overcome the conventional…”
Get full text

Antinociceptive role of neurotensin receptor 1 in rats with chemotherapy-induced peripheral neuropathy by Yin, Mei, Kim, Yeo-Ok, Choi, Jeong-Il, Jeong, Seongtae, Yang, Si-Ho, Bae, Hong-Beom, Yoon, Myung-Ha

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of anti-cancer drugs. Neurotensin receptors (NTSRs) are widely distributed within the…”
Get full text

EP121 Anti-allodynic effect of intrathecal administration of the antibodies to macrophage-inducible C-type lectin in spinal nerve ligation model of rat by Choi, Jeong Il, Yoon, Myung Ha, Jihoon, Yang

“…Anesthesiology and Pain Medicine, Chonnam National Universtiy Medical School and Hospital, Gwangju, KoreaBackground and AimsNeuroinflammation is regarded as a…”
Get full text

Ultrasound guided obturator nerve block: a single interfascial injection technique by Lee, Seong Heon, Jeong, Cheol Won, Lee, Hyun Jung, Yoon, Myung Ha, Kim, Woong Mo

“…We describe a new technique of single interfascial injection for 25 patients scheduled for transurethral bladder tumor resection. An ultrasound probe was…”
Get full text

EP110 Inhibition of NLRP3 inflammasome activation contributes to anti-allodynic effect of intrathecal gastrodin in spinal nerve ligation model of rat by Jin, Jun Xiu, Yoon, Myung Ha, Choi, Jeong Il

“…Background and AimsGastrodin (a main bioactive component of herbal plant, Gastrodia elata) has been shown to have beneficial effects in preclinical models of…”
Get full text

Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain by Lee, Hyung Gon, Kim, Yeo Ok, Choi, Jeong Il, Han, Xue Hao, Shin, Yang Un, Yoon, Myung Ha

“…Background: There is still unmet need in treating neuropathic pain and increasing awareness regarding the use of drug combinations to increase the…”
Get full text

Antinociceptive role of neurotensin receptor 1 in rats with chemotherapy-induced peripheral neuropathy by Yin, Mei, Kim, Yeo-Ok, Choi, Jeong-Il, Jeong, Seongtae, Yang, Si-Ho, Bae, Hong-Beom, Yoon, Myung-Ha

“…Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of anti-cancer drugs. Neurotensin receptors (NTSRs) are widely distributed…”
Get full text

Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla by Li, Yaqun, Kang, Dong Ho, Kim, Woong Mo, Lee, Hyung Gon, Kim, Seung Hoon, You, Hyun Eung, Choi, Jeong Il, Yoon, Myung Ha

“…Background: Supraspinal delivery of neurotensin (NTS), which may contribute to the effect of a systemically administered agonist, has been reported to be…”
Get full text

Prostaglandin D 2 contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord by Li, Yaqun, Kim, Woong Mo, Kim, Seung Hoon, You, Hyun Eung, Kang, Dong Ho, Lee, Hyung Gon, Choi, Jeong Il, Yoon, Myung Ha

“…Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major reason for stopping or changing anticancer therapy. Among the proposed…”
Get full text

Efficacy and Tolerability of Pregabalin Using a Flexible, Optimized Dose Schedule in Korean Patients With Peripheral Neuropathic Pain: A 10-Week, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study by Moon, Dong Eon, MD, Lee, Doo Ik, MD, PhD, Lee, Sang Chul, MD, Song, Sun Ok, MD, Yoon, Duck Mi, MD, Yoon, Myung Ha, MD, Kim, Hae Kyu, MD, Lee, Youn Woo, MD, Kim, Chan, MD, Lee, Pyung Bok, MD

“…Background Clinical trials from various countries have reported the efficacy of pregabalin for reducing peripheral neuropathic pain. Objective This study…”
Get full text

Effect of sec-O-glucosylhamaudol on mechanical allodynia in a rat model of postoperative pain by Koh, Gi-Ho, Song, Hyun, Kim, Sang Hun, Yoon, Myung Ha, Lim, Kyung Joon, Oh, Seon-Hee, Jung, Ki Tae

“…Background: This study was performed in order to examine the effect of intrathecal sec-O-glucosylhamaudol (SOG), an extract from the root of the Peucedanum…”
Get full text

Role of the 5-HT7 receptor in the effects of intrathecal nefopam in neuropathic pain in rats by Dam, Lee Jae, Hai, Lin, Ha, Yoon Myung

“…•Intrathecal nefopam attenuated mechanical allodynia by spinal nerve ligation.•The effect of nefopam was antagonized by 5-HT7 receptor antagonist.•Descending…”
Get full text

A New Rat Model of Cisplatin-induced Neuropathic Pain by Lin, Hai, Heo, Bong Ha, Yoon, Myung Ha

“…Background: Chemotherapy-induced peripheral neuropathy is a major side effect of anti-cancer drugs, and our knowledge of its mechanisms is lacking. Several…”
Get full text

Imbalance in the spinal serotonergic pathway induces aggravation of mechanical allodynia and microglial activation in carrageenan inflammation by Jin, Junxiu, Kang, Dong Ho, Jeon, Jin, Lee, Hyung Gon, Kim, Woong Mo, Yoon, Myung Ha, Choi, Jeong Il

“…This study investigated the effect of an excess and a deficit of spinal 5-hydroxytryptamine (5-HT) on the mechanical allodynia and neuroglia activation in a…”
Get full text

Antiallodynic effect through spinal endothelin-B receptor antagonism in rat models of complex regional pain syndrome by Kim, Yeo Ok, Kim, In Ji, Yoon, Myung Ha

“…•Each CRPS-I and -II rat model was made by O-ring application or by spinal nerve ligation.•The level of ET-1 in the spinal cord was increased in both CRPS…”
Get full text

Antinociceptive effect of intrathecal sec-O-glucosylhamaudol on the formalin-induced pain in rats by Kim, Sang Hun, Jong, Hwa Song, Yoon, Myung Ha, Oh, Seon Hee, Jung, Ki Tae

“…Background: The root of Peucedanum japonicum Thunb., a perennial herb found in Japan, the Philippines, China, and Korea, is used as an analgesic. In a previous…”
Get full text

Pharmacologic interaction between cannabinoid and either clonidine or neostigmine in the rat formalin test by Yoon, Myung Ha, Choi, Jeong Il

“…Although spinal cannabinoid receptor agonist (WIN 55,212-2) has been shown to encounter various models of pain, the role of two subtypes of cannabinoid…”
Get full text

Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain by Lee, Hyung Gon, Kim, Yeo Ok, Choi, Jeong Il, Han, Xue Hao, Shin, Yang Un, Yoon, Myung Ha

“…There is still unmet need in treating neuropathic pain and increasing awareness regarding the use of drug combinations to increase the effectiveness of…”
Get full text

The antiallodynic effect of intrathecal tianeptine is exerted by increased serotonin and norepinephrine in the spinal dorsal horn by Lee, Hyung Gon, Choi, Jeong Il, Yoon, Myung Ha, Obata, Hideaki, Saito, Shigeru, Kim, Woong Mo

“…•Intrathecal tianeptine reduced mechanical allodynia by spinal nerve ligation.•The tianeptine effect was reversed by serotonergic and adrenergic receptor…”
Get full text