Search Results - "Yoon, Kyung‐Sik"

Heat Shock Response and Heat Shock Proteins: Current Understanding and Future Opportunities in Human Diseases by Singh, Manish Kumar, Shin, Yoonhwa, Ju, Songhyun, Han, Sunhee, Choe, Wonchae, Yoon, Kyung-Sik, Kim, Sung Soo, Kang, Insug

“…The heat shock response is an evolutionarily conserved mechanism that protects cells or organisms from the harmful effects of various stressors such as heat,…”
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Characterization of a Parkinson’s disease rat model using an upgraded paraquat exposure paradigm by Cristóvão, Ana Clara, Campos, Filipa L., Je, Goun, Esteves, Marta, Guhathakurta, Subhrangshu, Yang, Lichuan, Beal, M. Flint, Fonseca, Beatriz M., Salgado, Antonio J., Queiroz, João, Sousa, Nuno, Bernardino, Liliana, Alves, Gilberto, Yoon, Kyung‐Sik, Kim, Yoon‐Seong

“…Animal models of human diseases are crucial experimental tools to investigate the mechanisms involved in disease pathogenesis and to develop new therapies. In…”
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Effective Differentiation of Induced Pluripotent Stem Cells Into Dental Cells by Kim, Eun‐Jung, Yoon, Kyung‐Sik, Arakaki, Makiko, Otsu, Keishi, Fukumoto, Satoshi, Harada, Hidemitsu, Green, David William, Lee, Jong‐Min, Jung, Han‐Sung

“…Background: A biotooth is defined as a complete living tooth, made in laboratory cultures from a spontaneous interplay between epithelial and mesenchymal…”
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Molecular Mechanisms for Ketone Body Metabolism, Signaling Functions, and Therapeutic Potential in Cancer by Hwang, Chi Yeon, Choe, Wonchae, Yoon, Kyung-Sik, Ha, Joohun, Kim, Sung Soo, Yeo, Eui-Ju, Kang, Insug

“…The ketone bodies (KBs) β-hydroxybutyrate and acetoacetate are important alternative energy sources for glucose during nutrient deprivation. KBs synthesized by…”
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Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases by Jang, Jiwon, Kim, Su Rim, Lee, Jo Eun, Lee, Seoyeon, Son, Hyeong Jig, Choe, Wonchae, Yoon, Kyung-Sik, Kim, Sung Soo, Yeo, Eui-Ju, Kang, Insug

“…Ketone bodies (KBs), such as acetoacetate and β-hydroxybutyrate, serve as crucial alternative energy sources during glucose deficiency. KBs, generated through…”
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AFM-detected apoptotic changes in morphology and biophysical property caused by paclitaxel in Ishikawa and HeLa cells by Kim, Kyung Sook, Cho, Chang Hoon, Park, Eun Kuk, Jung, Min-Hyung, Yoon, Kyung-Sik, Park, Hun-Kuk

“…The apoptosis of cancer cells is associated with changes in the important cell properties including morphology, surface roughness and stiffness. Therefore, the…”
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Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines by Dashdorj, Amarjargal, Jyothi, K R, Lim, Sangbin, Jo, Ara, Nguyen, Minh Nam, Ha, Joohun, Yoon, Kyung-Sik, Kim, Hyo Jong, Park, Jae-Hoon, Murphy, Michael P, Kim, Sung Soo

“…MitoQ is a mitochondria-targeted derivative of the antioxidant ubiquinone, with antioxidant and anti-apoptotic functions. Reactive oxygen species are involved…”
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Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans by Kim, Yeonghwan, Jang, Miran, Lim, Sangbin, Won, Hyeran, Yoon, Kyung‐Sik, Park, Jae‐Hoon, Kim, Hyo Jong, Kim, Byung‐Ho, Park, Won‐Sang, Ha, Joohun, Kim, Sung‐Soo

“…Cyclophilin B (CypB) performs diverse roles in living cells, but its role in hepatocellular carcinoma (HCC) is largely unclear. To reveal its role in HCC, we…”
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Apigenin protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis by Choi, A Young, Choi, Ji Hyun, Lee, Jung Yeon, Yoon, Kyung-Sik, Choe, Wonchae, Ha, Joohun, Yeo, Eui-Ju, Kang, Insug

“…Endoplasmic reticulum (ER) stress has been implicated in neurodegenerative diseases including Alzheimer's disease, Parkinson disease, and cerebral ischemia. In…”
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Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction by Choi, Ji Hyun, Choi, A Young, Yoon, Hana, Choe, Wonchae, Yoon, Kyung-Sik, Ha, Joohun, Yeo, Eui-Ju, Kang, Insug

“…Baicalein is one of the major flavonoids in Scutellaria baicalensis Georgi and possesses various effects, including cytoprotection and anti-inflammation…”
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Melatonin stimulates glucose transport via insulin receptor substrate-1/phosphatidylinositol 3-kinase pathway in C2C12 murine skeletal muscle cells by Ha, Eunyoung, Yim, Sung-Vin, Chung, Joo-Ho, Yoon, Kyung-Sik, Kang, Insug, Cho, Yong Ho, Baik, Hyung Hwan

“…:  The prevalence of diabetes has exponentially increased in recent decades due to environmental factors such as nocturnal lifestyle and aging, both of which…”
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Inhibition of AMP-activated Protein Kinase Sensitizes Cancer Cells to Cisplatin-induced Apoptosis via Hyper-induction of p53 by Kim, Hak-Su, Hwang, Jin-Taek, Yun, Hee, Chi, Sung-Gil, Lee, Su-Jae, Kang, Insug, Yoon, Kyung-Sik, Choe, Won-Jae, Kim, Sung-Soo, Ha, Joohun

“…Cisplatin is one of the most effective and widely used chemotherapeutic agents. However, one of the most salient limitations to the clinical application of…”
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FRET-based probing to gain direct information on siRNA sustainability in live cells: Asymmetric degradation of siRNA strands by Shin, Seonmi, Kwon, Hyun-Mi, Yoon, Kyung-Sik, Kim, Dong-Eun, Hah, Sang Soo

“…Investigation of the intracellular fate of small interference RNA (siRNA) following their delivery into cells is of great interest to elucidate dynamics of…”
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Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head by Kim, Hye- Ok, Cho, Chang- Hoon, Cho, Yoon- Je, Cho, Seong- Ho, Yoon, Kyung- Sik, Kim, Kang- Il

“…The pathogenesis of osteonecrosis of the femoral head (ONFH) has been implicated in hypofibrinolysis and blood supply interruption. Previous studies have…”
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Lipopolysaccharide induces hypoxia-inducible factor-1 alpha mRNA expression and activation via NADPH oxidase and Sp1-dependent pathway in BV2 murine microglial cells by Oh, Young Taek, Lee, Jung Yeon, Yoon, Hana, Lee, Eunjoo H., Baik, Hyung Hwan, Kim, Sung Soo, Ha, Joohun, Yoon, Kyung-Sik, Choe, Wonchae, Kang, Insug

“…Hypoxia-inducible factor-1 (HIF-1), the key transcription factor of hypoxia-inducible genes, is known to be involved in inflammation and immune response, but…”
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The association between panic disorder and the L/L genotype of catechol- O-methyltransferase by Woo, Jong-Min, Yoon, Kyung-Sik, Choi, Young-Hee, Oh, Kang-Sub, Lee, Young-Sik, Yu, Bum-Hee

“…To clarify the role of catechol- O-methyltransferase (COMT) polymorphism in panic disorder (PD), we investigated a large group of Korean PD patients ( N=178)…”
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Catechol O-Methyltransferase Genetic Polymorphism in Panic Disorder by Woo, Jong-Min, Yoon, Kyung-Sik, Yu, Bum-Hee

“…OBJECTIVE: The authors examined the distribution of catechol O-methyltransferase (COMT) genotypes in patients with panic disorder as well as the relationship…”
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Characterization of ultrastructure and collagen composition of the teratoma membrane: Comparison to the amniotic membrane by Kim, Kyung Sook, Cho, Chang-Hoon, Kim, Young-Sun, Yoon, Kyung-Sik, Jung, Min-Hyung, Park, Hun-Kuk

“…ABSTRACT The structural and morphological properties of the teratoma membrane were investigated to better understand the pathogenesis of ovarian teratomas. A…”
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Non-Polar Myxococcus fulvus KYC4048 Metabolites Exert Anti-Proliferative Effects via Inhibition of Wnt/β-Catenin Signaling in MCF-7 Breast Cancer Cells by Park, Juha, Yoo, Hee-Jin, Yu, Ah-Ran, Kim, Hye Ok, Park, Sang Cheol, Jang, Young Pyo, Lee, Chayul, Choe, Wonchae, Kim, Sung Soo, Kang, Insug, Yoon, Kyung-Sik

“…The Wnt/β-catenin signaling pathway is involved in breast cancer and Myxococcus fulvus KYC4048 is a myxobacterial strain that can produce a variety of…”
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RhoA/Rho Kinase Blocks Muscle Differentiation via Serine Phosphorylation of Insulin Receptor Substrate-1 and -2 by Lim, Min Jin, Choi, Kyu Jin, Ding, Yan, Kim, Jin Hwan, Kim, Bum Shik, Kim, Yun Hong, Lee, Jinhwa, Choe, Wonchae, Kang, Insug, Ha, Joohun, Yoon, Kyung-Sik, Kim, Sung Soo

“…Although the RhoA/Rho kinase (RhoA/ROK) pathway has been extensively investigated, its roles and downstream signaling pathways are still not well understood in…”
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