Search Results - "Yoon, Jong Bok"
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KDM3A histone demethylase functions as an essential factor for activation of JAK2−STAT3 signaling pathway
Published in Proceedings of the National Academy of Sciences - PNAS (13-11-2018)“…Janus tyrosine kinase 2 (JAK2)−signal transducer and activator of transcription 3 (STAT3) signaling pathway is essential for modulating cellular development,…”
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2
Osmotic Stress Inhibits Proteasome by p38 MAPK-dependent Phosphorylation
Published in The Journal of biological chemistry (31-12-2010)“…Osmotic stress causes profound perturbations of cell functions. Although the adaptive responses required for cell survival upon osmotic stress are being…”
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3
RNF167 targets Arl8B for degradation to regulate lysosome positioning and endocytic trafficking
Published in The FEBS journal (01-12-2016)“…The protease‐associated (PA) domain‐containing E3 ubiquitin ligases are transmembrane proteins located in intracellular organelles such as the endoplasmic…”
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4
Hypoxia-induced methylation of a pontin chromatin remodeling factor
Published in Proceedings of the National Academy of Sciences - PNAS (16-08-2011)“…Pontin is a chromatin remodeling factor that possesses both ATPase and DNA helicase activities. Although Pontin is frequently overexpressed in human cancers of…”
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The HECT Domain of TRIP12 Ubiquitinates Substrates of the Ubiquitin Fusion Degradation Pathway
Published in The Journal of biological chemistry (16-01-2009)“…The ubiquitin fusion degradation (UFD) pathway is a proteolytic system conserved in yeast and mammals in which an uncleavable ubiquitin moiety linked to the N…”
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6
Herp enhances ER-associated protein degradation by recruiting ubiquilins
Published in Biochemical and biophysical research communications (02-05-2008)“…ER-associated protein degradation (ERAD) is a protein quality control system of ER, which eliminates misfolded proteins by proteasome-dependent degradation and…”
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Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro
Published in FEBS letters (21-05-2004)“…Receptor interacting protein (RIP) is recruited to tumor necrosis factor-α receptor 1 (TNFR1) complex upon stimulation and plays a crucial role in the…”
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8
Reactivating the ARF-p53 axis in AML cells by targeting ULF
Published in Cell cycle (Georgetown, Tex.) (01-08-2010)“…The tumor suppressor ARF plays an essential role in the cellular response to oncogenic stress mainly through activation of p53. Nucleophosmin (NPM), a…”
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Fenretinide Ameliorates Insulin Resistance and Fatty Liver in Obese Mice
Published in Biological & pharmaceutical bulletin (2012)“…Fenretinide (FEN), a ligand of retinol binding protein 4 (RBP4), has been suggested as a measure to reduce insulin resistance and its associated disorders such…”
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10
Solution structure and Rpn1 interaction of the UBL domain of human RNA polymerase II C-terminal domain phosphatase
Published in PloS one (07-05-2013)“…The ubiquitin-like modifier (UBL) domain of ubiquitin-like domain proteins (UDPs) interacts specifically with subunits of the 26 S proteasome. A novel UDP,…”
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11
The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins
Published in The Journal of biological chemistry (12-07-2019)“…The E3 ubiquitin ligase membrane-associated ring-CH–type finger 2 (MARCH2) is known to be involved in intracellular vesicular trafficking, but its role in the…”
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12
RNF8 mediates NONO degradation following UV-induced DNA damage to properly terminate ATR-CHK1 checkpoint signaling
Published in Nucleic acids research (25-01-2019)“…Abstract RNF8 plays a critical role in DNA damage response (DDR) to initiate ubiquitination-dependent signaling. To better characterize the role of RNF8 in…”
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13
TOMM20 as a potential therapeutic target of colorectal cancer
Published in BMB reports (31-12-2019)“…Translocase of outer mitochondrial membrane 20 (TOMM20) plays an essential role as a receptor for proteins targeted to mitochondria. TOMM20 was shown to be…”
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TOMM20 as a potential therapeutic target of colorectal cancer
Published in BMB reports (01-12-2019)“…Translocase of outer mitochondrial membrane 20 (TOMM20) plays an essential role as a receptor for proteins targeted to mitochondria. TOMM20 was shown to be…”
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15
EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex
Published in Molecular cell (30-11-2012)“…Ubiquitination plays a major role in protein degradation. Although phosphorylation-dependent ubiquitination is well known for the regulation of…”
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16
The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair
Published in Molecular cell (01-03-2018)“…Double-strand breaks (DSBs) are critical DNA lesions that robustly activate the elaborate DNA damage response (DDR) network. We identified a critical player in…”
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Proteasomal ATPase-Associated Factor 1 Negatively Regulates Proteasome Activity by Interacting with Proteasomal ATPases
Published in Molecular and Cellular Biology (01-05-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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18
TIP120A Associates with Cullins and Modulates Ubiquitin Ligase Activity
Published in The Journal of biological chemistry (02-05-2003)“…The cullin-containing ubiquitin-protein isopeptide ligases (E3s) play an important role in regulating the abundance of key proteins involved in cellular…”
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Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis
Published in Science signaling (10-04-2012)“…Although the guanosine triphosphate/guanosine diphosphate loading switch is a major regulatory mechanism that controls the activity of the guanosine…”
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β-dystroglycan is regulated by a balance between WWP1-mediated degradation and protection from WWP1 by dystrophin and utrophin
Published in Biochimica et biophysica acta. Molecular basis of disease (01-06-2018)“…Dystroglycan is a ubiquitous membrane protein that functions as a mechanical connection between the extracellular matrix and cytoskeleton. In skeletal muscle,…”
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