Search Results - "Yoon, In Kyu"
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1
The mRNA vaccine development landscape for infectious diseases
Published in Nature reviews. Drug discovery (01-05-2022)Get full text
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The global epidemiology of chikungunya from 1999 to 2020: A systematic literature review to inform the development and introduction of vaccines
Published in PLoS neglected tropical diseases (01-01-2022)“…Chikungunya fever is an acute febrile illness that is often associated with severe polyarthralgia in humans. The disease is caused by chikungunya virus…”
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Reconstruction of antibody dynamics and infection histories to evaluate dengue risk
Published in Nature (London) (01-05-2018)“…As with many pathogens, most dengue infections are subclinical and therefore unobserved 1 . Coupled with limited understanding of the dynamic behaviour of…”
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Scientific rationale for developing potent RBD-based vaccines targeting COVID-19
Published in npj vaccines (28-10-2021)“…Vaccination of the global population against COVID-19 is a great scientific, logistical, and moral challenge. Despite the rapid development and authorization…”
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Detection of Zika Virus Infection in Thailand, 2012-2014
Published in The American journal of tropical medicine and hygiene (01-08-2015)“…Zika virus (ZIKV) is an emerging mosquito-borne pathogen with reported cases in Africa, Asia, and large outbreaks in the Pacific. No autochthonous ZIKV…”
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Evaluation of the extended efficacy of the Dengvaxia vaccine against symptomatic and subclinical dengue infection
Published in Nature Medicine (01-08-2021)“…More than half of the world’s population lives in areas at risk for dengue virus infection. A vaccine will be pivotal to controlling spread, however, the only…”
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Interactions between serotypes of dengue highlight epidemiological impact of cross-immunity
Published in Journal of the Royal Society interface (06-09-2013)“…Dengue, a mosquito-borne virus of humans, infects over 50 million people annually. Infection with any of the four dengue serotypes induces protective immunity…”
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A review of Dengvaxia®: development to deployment
Published in Human vaccines & immunotherapeutics (03-10-2019)“…Dengue is the world's most prevalent and important arboviral disease. More than 50% of the world's population lives at daily risk of infection and it is…”
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Dengue diversity across spatial and temporal scales: Local structure and the effect of host population size
Published in Science (American Association for the Advancement of Science) (24-03-2017)“…A fundamental mystery for dengue and other infectious pathogens is how observed patterns of cases relate to actual chains of individual transmission events…”
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Humoral Immunogenicity and Efficacy of a Single Dose of ChAdOx1 MERS Vaccine Candidate in Dromedary Camels
Published in Scientific reports (08-11-2019)“…MERS-CoV seronegative and seropositive camels received a single intramuscular dose of ChAdOx1 MERS, a replication-deficient adenoviral vectored vaccine…”
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Zika virus infection, Philippines, 2012
Published in Emerging infectious diseases (01-04-2015)Get full text
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Dengue virus seroprevalence study in Bangphae district, Ratchaburi, Thailand: A cohort study in 2012-2015
Published in PLoS neglected tropical diseases (01-01-2022)“…To determine the seroprevalence and transmission dynamics of dengue virus (DENV), age-stratified longitudinal serological surveys were conducted in Bangphae…”
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Pre-existing chikungunya virus neutralizing antibodies correlate with risk of symptomatic infection and subclinical seroconversion in a Philippine cohort
Published in International journal of infectious diseases (01-06-2020)“…•Chikungunya virus (CHIKV) outbreaks are unpredictable.•Linking pre-existing immune markers with subsequent CHIKV infection is difficult.•The current study…”
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Immune correlates of protection for dengue: State of the art and research agenda
Published in Vaccine (24-08-2017)“…Dengue viruses (DENV1-4) are mosquito-borne flaviviruses estimated to cause up to ∼400 million infections and ∼100 million dengue cases each year. Factors that…”
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High rate of subclinical chikungunya virus infection and association of neutralizing antibody with protection in a prospective cohort in the Philippines
Published in PLoS neglected tropical diseases (01-05-2015)“…Chikungunya virus (CHIKV) is a globally re-emerging arbovirus for which previous studies have indicated the majority of infections result in symptomatic…”
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Serotype-specific differences in the risk of dengue hemorrhagic fever: an analysis of data collected in Bangkok, Thailand from 1994 to 2006
Published in PLoS neglected tropical diseases (02-03-2010)“…It is unclear whether dengue serotypes differ in their propensity to cause severe disease. We analyzed differences in serotype-specific disease severity in…”
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Economic cost and burden of dengue in the Philippines
Published in The American journal of tropical medicine and hygiene (01-02-2015)“…Dengue, the world's most important mosquito-borne viral disease, is endemic in the Philippines. During 2008-2012, the country's Department of Health reported…”
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Determinants of inapparent and symptomatic dengue infection in a prospective study of primary school children in Kamphaeng Phet, Thailand
Published in PLoS neglected tropical diseases (01-03-2011)“…Dengue viruses are a major cause of morbidity in tropical and subtropical regions of the world. Inapparent dengue is an important component of the overall…”
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Clinical and epidemiologic characteristics associated with dengue during and outside the 2016 outbreak identified in health facility-based surveillance in Ouagadougou, Burkina Faso
Published in PLoS neglected tropical diseases (01-12-2019)“…In Africa, the magnitude of dengue virus (DENV) transmission is largely unknown. In Burkina Faso, several outbreaks have been reported and data are often based…”
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Novel Assay to Measure Seroprevalence of Zika Virus in the Philippines
Published in Emerging infectious diseases (01-12-2021)“…Zika virus (ZIKV) is a member of the Flaviviridae family, which includes other clinically notable viruses such as the 4 dengue virus serotypes (DENV-1-4)…”
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