Search Results - "Yoon, Dong Suk"
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Cell recruiting chemokine-loaded sprayable gelatin hydrogel dressings for diabetic wound healing
Published in Acta biomaterialia (01-07-2016)“…[Display omitted] In this study, we developed horseradish peroxidase (HRP)-catalyzed sprayable gelatin hydrogels (GH) as a bioactive wound dressing that can…”
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SIRT1 Directly Regulates SOX2 to Maintain Self‐Renewal and Multipotency in Bone Marrow‐Derived Mesenchymal Stem Cells
Published in Stem cells (Dayton, Ohio) (01-12-2014)“…SOX2 is crucial for the maintenance of the self‐renewal capacity and multipotency of mesenchymal stem cells (MSCs); however, the mechanism by which SOX2 is…”
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3
Non-Ionic Surfactants Antagonize Toxicity of Potential Phenolic Endocrine-Disrupting Chemicals, Including Triclosan in Caenorhabditis elegans
Published in Molecules and cells (2018)“…Triclosan (TCS) is a phenolic antimicrobial chemical used in consumer products and medical devices. Evidence from in vitro and in vivo animal studies has…”
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A Phenotype-Based RNAi Screening for Ras-ERK/MAPK Signaling-Associated Stem Cell Regulators in C. elegans
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…Stem cells have the ability to self-renew and to generate differentiated cell types. A regulatory network that controls this balance is critical for stem cell…”
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Downregulation of the RNA-binding protein PUM2 facilitates MSC-driven bone regeneration and prevents OVX-induced bone loss
Published in Journal of biomedical science (23-04-2023)“…Although mRNA dysregulation can induce changes in mesenchymal stem cell (MSC) homeostasis, the mechanisms by which post-transcriptional regulation influences…”
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Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions
Published in Bioactive materials (01-01-2024)“…Regeneration of pathological wounds, such as diabetic ulcers, poses a significant challenge in clinical settings, despite the widespread use of drugs. To…”
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Characterization of different subpopulations from bone marrow-derived mesenchymal stromal cells by alkaline phosphatase expression
Published in Stem cells and development (01-11-2012)“…Multiple surface markers have been utilized for the enrichment of bone marrow mesenchymal stromal cells (MSCs) and to define primitive stem cells. We…”
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In Situ Recruitment of Human Bone Marrow-Derived Mesenchymal Stem Cells Using Chemokines for Articular Cartilage Regeneration
Published in Cell transplantation (01-06-2015)“…Bone marrow-derived mesenchymal stem cells (BMSCs) are a good cell source for regeneration of cartilage as they can migrate directly to the site of cartilage…”
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Interleukin‐6 induces the lineage commitment of bone marrow‐derived mesenchymal multipotent cells through down‐regulation of Sox2 by osteogenic transcription factors
Published in The FASEB journal (01-07-2014)“…ABSTRACT Bone marrow‐derived mesenchymal stromal cells (BM‐MSCs) are a heterogeneous population of cells that differ in size and morphology. BM‐MSCs become…”
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Characterization of adipose tissue-derived stromal vascular fraction for clinical application to cartilage regeneration
Published in In vitro cellular & developmental biology. Animal (01-02-2015)“…Bone marrow concentration (BMC) is the most recognized procedure to prepare mesenchymal stem cells for cartilage regeneration. However, bone marrow aspiration…”
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miR-449a regulates the chondrogenesis of human mesenchymal stem cells through direct targeting of lymphoid enhancer-binding factor-1
Published in Stem cells and development (10-12-2012)“…microRNAs are small molecules, about 17-23 nucleotides in length, that act as translational regulators of their target gene. By binding to a target, microRNAs…”
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Development of stabilized dual growth factor-loaded hyaluronate collagen dressing matrix
Published in Journal of tissue engineering (2021)“…Patients with diabetes experience impaired growth factor production such as epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF), and they…”
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Promoting angiogenesis and diabetic wound healing through delivery of protein transduction domain-BMP2 formulated nanoparticles with hydrogel
Published in Journal of tissue engineering (01-01-2023)“…Decreased angiogenesis contributes to delayed wound healing in diabetic patients. Recombinant human bone morphogenetic protein-2 (rhBMP2) has also been…”
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14
Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway
Published in Cell communication and signaling (02-10-2013)“…Zinc, an essential trace element, inhibits osteoclast differentiation in vitro and in vivo. The molecular mechanism for the inhibitory effect of zinc, however,…”
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Synergistic Action of IL-8 and Bone Marrow Concentrate on Cartilage Regeneration Through Upregulation of Chondrogenic Transcription Factors
Published in Tissue engineering. Part A (01-02-2016)“…The objective of this study was to determine whether a biphasic scaffold loaded with a combination of a chemokine and bone marrow concentrate (BMC) could…”
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Drug repositioning of polaprezinc for bone fracture healing
Published in Communications biology (16-05-2022)“…Fractures and related complications are a common challenge in the field of skeletal tissue engineering. Vitamin D and calcium are the only broadly available…”
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The effects of COX-2 inhibitor during osteogenic differentiation of bone marrow-derived human mesenchymal stem cells
Published in Stem cells and development (01-10-2010)“…Cyclooxygenase-2 (COX-2) inhibitors suppress bone repair and bone formation by suppressing angiogenesis as well as potentially interfering with osteoblast and…”
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TLR4 downregulation by the RNA-binding protein PUM1 alleviates cellular aging and osteoarthritis
Published in Cell death and differentiation (01-07-2022)“…Dysfunction of mRNA or RNA-binding proteins (RBPs) causes cellular aging and age-related degenerative diseases; however, information regarding the mechanism…”
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Dual actions of osteoclastic-inhibition and osteogenic-stimulation through strontium-releasing bioactive nanoscale cement imply biomaterial-enabled osteoporosis therapy
Published in Biomaterials (01-09-2021)“…Repair of defective hard-tissues in osteoporotic patients faces significantly challenges with limited therapeutic options. Although biomedical cements are…”
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Diabetic bone regeneration with nanoceria-tailored scaffolds by recapitulating cellular microenvironment: Activating integrin/TGF-β co-signaling of MSCs while relieving oxidative stress
Published in Biomaterials (01-09-2022)“…Regenerating defective bone in patients with diabetes mellitus remains a significant challenge due to high blood glucose level and oxidative stress. Here we…”
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