Search Results - "Yoon, Christopher J"

Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics by Radovic-Moreno, Aleksandar F, Lu, Timothy K, Puscasu, Vlad A, Yoon, Christopher J, Langer, Robert, Farokhzad, Omid C

“…Bacteria have shown a remarkable ability to overcome drug therapy if there is a failure to achieve sustained bactericidal concentration or if there is a…”
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Co-evolution of tumor and immune cells during progression of multiple myeloma by Liu, Ruiyang, Gao, Qingsong, Foltz, Steven M., Fowles, Jared S., Yao, Lijun, Wang, Julia Tianjiao, Cao, Song, Sun, Hua, Wendl, Michael C., Sethuraman, Sunantha, Weerasinghe, Amila, Rettig, Michael P., Storrs, Erik P., Yoon, Christopher J., Wyczalkowski, Matthew A., McMichael, Joshua F., Kohnen, Daniel R., King, Justin, Goldsmith, Scott R., O’Neal, Julie, Fulton, Robert S., Fronick, Catrina C., Ley, Timothy J., Jayasinghe, Reyka G., Fiala, Mark A., Oh, Stephen T., DiPersio, John F., Vij, Ravi, Ding, Li

“…Multiple myeloma (MM) is characterized by the uncontrolled proliferation of plasma cells. Despite recent treatment advances, it is still incurable as disease…”
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Evolution and structure of clinically relevant gene fusions in multiple myeloma by Foltz, Steven M., Gao, Qingsong, Yoon, Christopher J., Sun, Hua, Yao, Lijun, Li, Yize, Jayasinghe, Reyka G., Cao, Song, King, Justin, Kohnen, Daniel R., Fiala, Mark A., Ding, Li, Vij, Ravi

“…Multiple myeloma is a plasma cell blood cancer with frequent chromosomal translocations leading to gene fusions. To determine the clinical relevance of fusion…”
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Discovery of driver non-coding splice-site-creating mutations in cancer by Cao, Song, Zhou, Daniel Cui, Oh, Clara, Jayasinghe, Reyka G., Zhao, Yanyan, Yoon, Christopher J., Wyczalkowski, Matthew A., Bailey, Matthew H., Tsou, Terrence, Gao, Qingsong, Malone, Andrew, Reynolds, Sheila, Shmulevich, Ilya, Wendl, Michael C., Chen, Feng, Ding, Li

“…Non-coding mutations can create splice sites, however the true extent of how such somatic non-coding mutations affect RNA splicing are largely unexplored. Here…”
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Germline gain-of-function mutation of STAT1 rescued by somatic mosaicism in immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like disorder by Lee, Jeong Seok, An, Yohan, Yoon, Christopher J., Kim, Jeong Yeon, Kim, Kyung Hwan, Freeman, Alexandra F., Yim, Jae-Joon, Shin, Eui-Cheol, Holland, Steven M., Lee, Eun Young, Ju, Young Seok

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GenomeVIP: a cloud platform for genomic variant discovery and interpretation by Mashl, R Jay, Scott, Adam D, Huang, Kuan-Lin, Wyczalkowski, Matthew A, Yoon, Christopher J, Niu, Beifang, DeNardo, Erin, Yellapantula, Venkata D, Handsaker, Robert E, Chen, Ken, Koboldt, Daniel C, Ye, Kai, Fenyö, David, Raphael, Benjamin J, Wendl, Michael C, Ding, Li

“…Identifying genomic variants is a fundamental first step toward the understanding of the role of inherited and acquired variation in disease. The accelerating…”
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Whole-genome sequences reveal zygotic composition in chimeric twins by Yoon, Christopher J., Nam, Chang Hyun, Kim, Taewoo, Lee, Jeong Seok, Kim, Ryul, Yi, Kijong, Koh, June-Young, Kim, Jiye, Won, Hyein, Oh, Ji Won, Griffith, Obi L., Griffith, Malachi, Sung, Joohon, Kim, Tae Yeul, Cho, Duck, Choi, Ji Seon, Ju, Young Seok

“…While most dizygotic twins have a dichorionic placenta, rare cases of dizygotic twins with a monochorionic placenta have been reported. The monochorionic…”
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Mitochondrial DNA mosaicism in normal human somatic cells by An, Jisong, Nam, Chang Hyun, Kim, Ryul, Lee, Yunah, Won, Hyein, Park, Seongyeol, Lee, Won Hee, Park, Hansol, Yoon, Christopher J., An, Yohan, Kim, Jie-Hyun, Jun, Jong Kwan, Bae, Jeong Mo, Shin, Eui-Cheol, Kim, Bun, Cha, Yong Jun, Kwon, Hyun Woo, Oh, Ji Won, Park, Jee Yoon, Kim, Min Jung, Ju, Young Seok

“…Somatic cells accumulate genomic alterations with age; however, our understanding of mitochondrial DNA (mtDNA) mosaicism remains limited. Here we investigated…”
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Estimation of intrafamilial DNA contamination in family trio genome sequencing using deviation from Mendelian inheritance by Yoon, Christopher J, Kim, Su Yeon, Nam, Chang Hyun, Lee, Junehawk, Park, Jung Woo, Mun, Jihyeob, Park, Seongyeol, Lee, Soyoung, Yi, Boram, Min, Kyoung Il, Wiley, Brian, Bolton, Kelly L, Lee, Jeong Ho, Kim, Eunjoon, Yoo, Hee Jeong, Jun, Jong Kwan, Choi, Ji Seon, Griffith, Malachi, Griffith, Obi L, Ju, Young Seok

“…With the increasing number of sequencing projects involving families, quality control tools optimized for family genome sequencing are needed. However,…”
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Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers by Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J., Yang, Yang, Martincorena, Inigo, Creighton, Chad J., Weinstein, John N., Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J., Liang, Han

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers by Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J., Yang, Yang, Martincorena, Inigo, Creighton, Chad J., Weinstein, John N., Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J., Liang, Han

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers by Mundt, Filip, Rajput, Sandeep, Li, Shunqiang, Ruggles, Kelly V, Mooradian, Arshag D, Mertins, Philipp, Gillette, Michael A, Krug, Karsten, Guo, Zhanfang, Hoog, Jeremy, Erdmann-Gilmore, Petra, Primeau, Tina, Huang, Shixia, Edwards, Dean P, Wang, Xiaowei, Wang, Xuya, Kawaler, Emily, Mani, D R, Clauser, Karl R, Gao, Feng, Luo, Jingqin, Davies, Sherri R, Johnson, Gary L, Huang, Kuan-Lin, Yoon, Christopher J, Ding, Li, Fenyö, David, Ellis, Matthew J, Townsend, R Reid, Held, Jason M, Carr, Steven A, Ma, Cynthia X

“…Activation of PI3K signaling is frequently observed in triple-negative breast cancer (TNBC), yet PI3K inhibitors have shown limited clinical activity. To…”
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Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers by Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J., Yang, Yang, Martincorena, Inigo, Creighton, Chad J., Weinstein, John N., Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J., Liang, Han

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Comprehensive Multi-Omics Analysis of Gene Fusions in a Large Multiple Myeloma Cohort by Foltz, Steven M., Gao, Qingsong, Yoon, Christopher J., Weerasinghe, Amila, Sun, Hua, Yao, Lijun, Fiala, Mark A., Kohnen, Daniel R., King, Justin, Ju, Yeong Seok, DiPersio, John F., Vij, Ravi, Ding, Li

“…Introduction: Gene fusions are the result of genomic rearrangements that create hybrid protein products or bring the regulatory elements of one gene into close…”
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Genomic and Immune Profiles of Multiple Myeloma Revealed By Whole Genome and Transcriptome Sequencing by Yoon, Christopher J., Song, Hyojin, Song, Seulki, Park, Hyejoo, Shin, Dong-Yeop, Hong, Junshik, Kim, Inho, Lee, Hyun Jung, Kim, Byung-Su, Lee, Jung Lim, Yoon, Sung-Soo, Ju, Young Seok, Koh, Youngil

“…Introduction: We analyzed genomic profile in line with immune checkpoint molecule expression in multiple myeloma using whole genome sequencing (WGS) and whole…”
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Uncovering Clonal and Subclonal Druggable Targets in Multiple Myeloma Using Omic Data by Scott, Adam David, Yellapantula, Venkata D, Yoon, Christopher J, Wendl, Michael, Tomasson, Michael H., Fiala, Mark A, DiPersio, John F., Vij, Ravi, Ding, Li

“…The Multiple Myeloma Research Foundation (MMRF) CoMMpass trial is the keystone program working towards personalized medicine in multiple myeloma (MM). CoMMpass…”
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Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers by Mundt, Filip, Rajput, Sandeep, Li, Shunqiang, Ruggles, Kelly, Mooradian, Arshag D., Mertins, Philipp, Gillette, Michael A., Krug, Karsten, Guo, Zhanfang, Hoog, Jeremy, Erdmann-Gilmore, Petra, Primeau, Tina, Huang, Shixia, Edwards, Dean P., Wang, Xiaowei, Wang, Xuya, Kawaler, Emily, Mani, D R., Clauser, Karl R., Gao, Feng, Luo, Jingqin, Davies, Sherri R., Johnson, Gary L., Huang, Kuan-lin, Yoon, Christopher J., Ding, Li, Fenyö, David, Ellis, Matthew J., Townsend, R. Reid, Held, Jason M., Carr, Steven A., Ma, Cynthia X.

“…Activation of phosphoinositide 3-kinase (PI3K) signaling is frequently observed in triple-negative breast cancer (TNBC), yet PI3K inhibitors have shown limited…”
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Germline gain-of-function mutation of STAT1 rescued by somatic mosaicism in immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like disorder by Lee, Jeong Seok, An, Yohan, Yoon, Christopher J, Kim, Jeong Yeon, Kim, Kyung Hwan, Freeman, Alexandra F, Yim, Jae-Joon, Shin, Eui-Cheol, Holland, Steven M, Lee, Eun Young, Ju, Young Seok

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