Search Results - "Yoo-na Kim"
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Maternal age and risk of early neonatal mortality: a national cohort study
Published in Scientific reports (12-01-2021)“…Advanced maternal age (AMA) is a growing trend world-wide and is traditionally defined as childbearing in women over 35 years of age. The purpose of our study…”
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Randomized, two‐arm, noncomparative phase 2 study of olaparib plus cediranib or durvalumab in HRR ‐mutated, platinum‐resistant ovarian cancer: A substudy of KGOG 3045
Published in International journal of cancer (15-12-2023)“…Abstract Choosing an optimal concomitant drug for combination with poly‐ADP ribose polymerase (PARP) inhibitor based on patient‐specific biomarker status may…”
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Human epidermal growth factor receptor-2 expression and subsequent dynamic changes in patients with ovarian cancer
Published in Scientific reports (05-04-2024)“…Human epidermal growth factor receptor-2 (HER2)-targeting drugs are increasingly being incorporated into therapeutic paradigms for non-breast cancers, yet…”
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Predicting labor induction success by cervical funneling in uncomplicated pregnancies
Published in The journal of obstetrics and gynaecology research (01-07-2020)“…Aim Predictive accuracy of cervical funneling for successful vaginal delivery prior to labor induction was compared to that of conventional methods such as…”
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Triplet maintenance therapy of olaparib, pembrolizumab and bevacizumab in women with BRCA wild-type, platinum-sensitive recurrent ovarian cancer: the multicenter, single-arm phase II study OPEB-01/APGOT-OV4
Published in Nature communications (06-09-2023)“…In this multicenter, open-label, single-arm, Phase II study with Simon two-stage optimum design (NCT04361370), we investigate the efficacy and safety of…”
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The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples
Published in Nature communications (01-02-2022)“…Genetic and non-genetic factors contribute to breast cancer development. An epigenome-based signature capturing these components in easily accessible samples…”
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Sentinel lymph node biopsy in high-risk endometrial cancer: performance, outcomes, and future avenues
Published in Obstetrics & gynecology science (01-09-2022)“…Endometrial cancer is the second most common gynecological malignancy worldwide, with an overall favorable prognosis. However, a subgroup of patients has a…”
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Dynamics of the Tumor Immune Microenvironment during Neoadjuvant Chemotherapy of High-Grade Serous Ovarian Cancer
Published in Cancers (06-05-2022)“…The dynamic changes in the tumor immune microenvironment (TIME) triggered by neoadjuvant chemotherapy (NAC) have not been clearly defined in advanced-stage…”
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Genomic hypomethylation in cell-free DNA predicts responses to checkpoint blockade in lung and breast cancer
Published in Scientific reports (18-12-2023)“…Genomic hypomethylation has recently been identified as a determinant of therapeutic responses to immune checkpoint blockade (ICB). However, it remains unclear…”
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Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock
Published in Genome Biology (22-02-2022)“…A variety of epigenetic clocks utilizing DNA methylation changes have been developed; these clocks are either tissue-independent or designed to predict…”
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RAD51 as an immunohistochemistry-based marker of poly(ADP-ribose) polymerase inhibitor resistance in ovarian cancer
Published in Frontiers in oncology (25-04-2024)“…Effective functional biomarkers that can be readily used in clinical practice to predict poly(ADP-ribose) polymerase inhibitor (PARPi) sensitivity are lacking…”
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Abnormal lymphatic vessel development is associated with decreased decidual regulatory T cells in severe preeclampsia
Published in American journal of reproductive immunology (1989) (01-07-2018)“…Problem The lymphatic vasculature controls leukocytes trafficking and limits the adaptive immune response. In previous models of preeclampsia (PE), defective…”
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RAD51/geminin/γH2AX immunohistochemical expression predicts platinum-based chemotherapy response in ovarian high-grade serous carcinoma
Published in Journal of gynecologic oncology (01-07-2023)“…The RAD51 assay is a recently developed functional assay for homologous recombination deficiency (HRD) that reflects real-time HRD status. We aimed to identify…”
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Clinical Relevance of Uterine Manipulation on Oncologic Outcome in Robot-Assisted versus Open Surgery in the Management of Endometrial Cancer
Published in Journal of clinical medicine (01-03-2023)“…In this study, we investigated the impact of uterine manipulation on endometrial cancer survival outcomes. We analyzed patients with endometrial cancer who…”
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Author Correction: Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock
Published in Genome Biology (29-06-2022)Get full text
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Comprehensive genomic and immunohistochemical profiles and outcomes of immunotherapy in patients with recurrent or advanced cervical cancer
Published in Frontiers in oncology (15-05-2023)“…This study aimed to investigate genomic and immunohistochemical (IHC) profiles and immunotherapy outcomes in patients with cervical cancer. Patients with…”
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Sentinel lymph node biopsy in high-risk endometrial cancer: performance, outcomes, and future avenues
Published in Obstetrics & gynecology science (30-09-2022)“…Endometrial cancer is the second most common gynecological malignancy worldwide, with an overall favorable prognosis. However, a subgroup of patients has a…”
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Feasibility and clinical applicability of genomic profiling based on cervical smear samples in patients with endometrial cancer
Published in Frontiers in oncology (05-08-2022)“…Purpose Cervical smear samples are easily obtainable and may effectively reflect the tumor microenvironment in gynecological cancers. Therefore, we…”
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Identification of Lynch Syndrome in Patients with Endometrial Cancer Based on a Germline Next Generation Sequencing Multigene Panel Test
Published in Cancers (13-07-2022)“…We aimed to investigate the prevalence and relative contributions of LS and non-LS mutations in patients with endometrial cancer in Korea. We retrospectively…”
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