Search Results - "Yoo, Moohi"

Effects of phosphodiesterase type 5 inhibitor on the contractility of prostate tissues and urethral pressure responses in a rat model of benign prostate hyperplasia by Kang, Kyung K, Kim, Ju M, Yu, Jae Y, Ahn, Byoung O, Yoo, Moohi, Kim, Young C

“…Aim:  This study was performed to investigate the effect of DA‐8159, a selective phosphodiesterase 5 (PDE5) inhibitor, on benign prostatic hyperplasia (BPH)…”
Get full text

Inhibitory Effect of DA-9201, an Extract of Oryza sativa L., on Airway Inflammation and Bronchial Hyperresponsiveness in Mouse Asthma Model by Lee, Seung-Ho, Sohn, Yong Sung, Kang, Kyung Koo, Kwon, Jong Won, Yoo, Moohi

“…Asthma is one of the major public health problems worldwide and the morbidity and mortality of asthma has increased in the past two decades. Accumulating data…”
Get full text

Beneficial effects of the combination of amlodipine and losartan for lowering blood pressure in spontaneously hypertensive rats by Choi, Seul Min, Seo, Mi Jeong, Kang, Kyung Koo, Kim, Jeong Hoon, Ahn, Byoung Ok, Yoo, Moohi

“…A combination of antihypertensive agents can better control blood pressure and reduce the number and severity of side effects than a monotherapy. Since both…”
Get full text

Pharmacokinetics of DA-7218, a new oxazolidinone, and its active metabolite, DA-7157, after intravenous and oral administration of DA-7218 and DA-7157 to rats by Bae, Soo K., Yang, Si H., Shin, Karen N., Rhee, Jae K., Yoo, Moohi, Lee, Myung G.

“…DA‐7218 (a prodrug of DA‐7157), a new oxazolidinone, was hydrolysed via phosphatase to form its active metabolite, DA‐7157, in rats. The pharmacokinetic…”
Get full text

Penile erectile responses to electric stimulation are enhanced by a new phosphodiesterase type-5 inhibitor by YU, JAE YOUNG, KANG, KYUNG KOO, YOO, MOOHI, KWON, JONG WON

“…Aim:  This study was conducted to investigate the effect of DA‐8159, a new phosphodiesterase type‐5 (PDE5) inhibitor, on electrostimulation‐induced penile…”
Get full text

Transport of a new erectogenic udenafil in Caco-2 cells by Ji, Hye Young, Shim, Hyun Joo, Yoo, Moohi, Park, Eun-Seok, Lee, Hye Suk

“…P-glycoprotein, an ATP-dependent efflux pump, is a membrane transporter that influences the absorption and excretion of drugs. There is a striking overlap…”
Get full text

Determination of a new phosphodiesterase V inhibitor, DA-8159, in plasma and urine by high-performance liquid chromatography by Shim, Hyun Joo, Lee, Eun Joo, Jung, Young Hee, Kim, So Hee, Kim, Soon Hoe, Yoo, Moohi, Kwon, Jong Won, Kim, Won Bae, Lee, Myung Gull

“…A high-performance liquid chromatographic (HPLC) method using liquid–liquid extraction for sample preparation was developed for the determination of a new…”
Get full text

In Vitro and In Vivo Activities of DA-7867, a New Oxazolidinone, against Aerobic Gram-Positive Bacteria by Yoon, Eun Jeong, Jo, Yeong Woo, Choi, Sung Hak, Lee, Tae Ho, Rhee, Jae Keol, Yoo, Moohi, Shim, Mi Ja, Choi, Eung Chil

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Erectile potentials of a new phosphodiesterase type 5 inhibitor, DA-8159, in diet-induced obese rats by Yu, Jae‐Young, Kang, Kyung‐Koo, Yoo, Moohi

“…Aim： To examine the changes in the erectile function in diet-induced obese rats and investigate the oral efficacy of DA-8159, a new phosphodiesterase type 5…”
Get full text

Asymmetric Cyclopropanation Using New Chiral Auxiliaries Derived from D-Fructose by Kang, Jahyo, Lim, Geun Jho, Yoon, Suk Kyoon, Kim, Moohi Yoo

Get full text

Erectogenic effect of the selective phosphodiesterase type 5 inhibitor, DA-8159 by Oh, T Y, Kang, K K, Ahn, B O, Yoo, M, Kim, W B

“…DA-8159, a new phosphodiesterase 5 inhibitor, was assessed for its erectogenic potential by a penile erection test in rats, the relaxation of isolated rabbit…”
Get full text

Negligible pharmacokinetic interaction between oral DA-8159, a new erectogenic, and amlodipine in rats by Lee, Joo H., Kim, Eun J., Kwon, Jong W., Yoo, Moohi, Lee, Myung G.

“…A pharmacokinetic interaction between oral DA‐8159 and amlodipine was evaluated in male Sprague–Dawley rats. In rats pretreated with troleandomycin (a main…”
Get full text

Effect of DA-6034, a derivative of flavonoid, on experimental animal models of inflammatory bowel disease by Kim, Y S, Son, M, Ko, J I, Cho, H, Yoo, M, Kim, W B, Song, I S, Kim, C Y

“…Inflammatory bowel disease (IBD) is a multifactorial disorder with unknown etiology and pathogenesis. DA-6034, 7-carboxymethyloxy-3', 4', 5-trimethoxy flavone,…”
Get full text

DA-9201 Shows Anti-Asthmatic Effects by Suppressing NF-$\kappa$B Expression in an Ovalbumin-Induced Mouse Model of Asthma by Lee Seung-Ho, Seo Mi Jung, Choi Seul Min, Sohn Yong Sung, Kang Kyung Koo, Ahn Byoung Ok, Kwon Jong Won, Yoo Moohi

“…Nuclear factor kappa B (NF-$\kappa$B) regulates the expression of multiple cytokines, chemokines, and cell adhesion molecules that are involved in the…”
Get full text

The Therapeutic Effect of DA-6034 on Ocular Inflammation via Suppression of MMP-9 and Inflammatory Cytokines and Activation of the MAPK Signaling Pathway in an Experimental Dry Eye Model by Seo, Mi Jeong, Kim, Ju Mi, Lee, Min Jung, Sohn, Yong Sung, Kang, Kyung Koo, Yoo, Moohi

“…Purpose: To investigate the effect of DA-6034, 7-carboxymethyloxy-3′,4′,5-trimethoxy flavone, in experimentally-induced inflammatory dry eye in rabbit. In…”
Get full text

Discovery of DA-1229: A potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes by Kim, Heung Jae, Kwak, Woo Young, Min, Jong Pil, Lee, Jae Young, Yoon, Tae Hyun, Kim, Ha Dong, Shin, Chang Yell, Kim, Mi Kyung, Choi, Song Hyen, Kim, Hae Sun, Yang, Eun Kyoung, Cheong, Ye Hwang, Chae, Yu Na, Park, Kyung Jin, Jang, Ji Myun, Choi, Soo Jung, Son, Moon Ho, Kim, Soon Hoe, Yoo, Moohi, Lee, Bong Jin

“…The synthesis and SAR studies of β-amino amide DPP-4 inhibitor 5f are reported. A series of β-amino amide containing substituted piperazine-2-one derivatives…”
Get full text

Gastroprotective effects of DA-6034, a new flavonoid derivative, in various gastric mucosal damage models by SEUL MIN CHOI, JEE HYUN SHIN, KYUNG KOO KANG, BYOUNG OK AHN, YOO, Moohi

“…This study evaluated the gastroprotective activity of DA-6034 against various ulcerogens including ethanol, aspirin, indomethacin, stress, and acetic acid. The…”
Get full text

Gastroretentive drug delivery system of DA-6034, a new flavonoid derivative, for the treatment of gastritis by Jang, Sun Woo, Lee, Jung Woo, Park, Sung Hyun, Kim, Jeong Hoon, Yoo, Moohi, Na, Dong Hee, Lee, Kang Choon

“…A gastroretentive drug delivery system of DA-6034, a new synthetic flavonoid derivative, for the treatment of gastritis was developed by using effervescent…”
Get full text

Udenafil Enhances the Recovery of Erectile Function and Ameliorates the Pathophysiological Consequences of Cavernous Nerve Resection by Lee, Chan-Ho, Shin, Jee-Hyun, Ahn, Gook-Jun, Kang, Kyung-Koo, Ahn, Byoung-Ok, Yoo, Moohi

“…Radical prostatectomy is the treatment of choice for prostate cancer patients. Despite the introduction of nerve-sparing surgical techniques, its success is…”
Get full text

Long-acting interferon-α 2a modified with a trimer-structured polyethylene glycol: Preparation, in vitro bioactivity, in vivo stability and pharmacokinetics by Jo, Yeong Woo, Youn, Yu Seok, Lee, Sung Hee, Kim, Byong Moon, Kang, Soo Hyung, Yoo, Moohi, Choi, Eung Chil, Lee, Kang Choon

“…The proper selection of size and shape for polyethylene glycol (PEG) is one of the most important points in PEGylation technology. Therefore, PEGs of various…”
Get full text