Search Results - "Yoo, Edwin J"

Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link? by Ojiaku, Christie A, Yoo, Edwin J, Panettieri, Jr, Reynold A

“…The pathogenesis of asthma includes a complex interplay among airway inflammation, hyperresponsiveness, and remodeling. Current evidence suggests that airway…”
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Phosphoinositide 3-Kinase in Asthma: Novel Roles and Therapeutic Approaches by Yoo, Edwin J, Ojiaku, Christie A, Sunder, Krishna, Panettieri, Jr, Reynold A

“…Asthma manifests as airway hyperresponsiveness and inflammation, including coughing, wheezing, and shortness of breath. Immune cells and airway structural…”
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TGF-β1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3 by Ojiaku, Christie A, Cao, Gaoyuan, Zhu, Wanqu, Yoo, Edwin J, Shumyatcher, Maya, Himes, Blanca E, An, Steven S, Panettieri, Jr, Reynold A

“…Transforming growth factor β1 (TGF-β1), a cytokine whose levels are elevated in the airways of patients with asthma, perpetuates airway inflammation and…”
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Tackling the Heterogeneity of Heart Failure with Preserved Ejection Fraction Using Proteomic Profiling by YOO, EDWIN J., HAHN, VIRGINIA SHALKEY

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Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction by Hahn, Virginia S., Petucci, Christopher, Kim, Min-Soo, Bedi, Kenneth C., Wang, Hanghang, Mishra, Sumita, Koleini, Navid, Yoo, Edwin J., Margulies, Kenneth B., Arany, Zoltan, Kelly, Daniel P., Kass, David A., Sharma, Kavita

“…The human heart primarily metabolizes fatty acids, and this decreases as alternative fuel use rises in heart failure with reduced ejection fraction (HFrEF)…”
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Advances in proteomics methods for the analysis of exhaled breath condensate by Yoo, Edwin J., Kim, Julie S., Stransky, Stephanie, Spivack, Simon, Sidoli, Simone

“…The analysis of exhaled breath condensate (EBC) demonstrates a promising avenue of minimally invasive biopsies for diagnostics. EBC is obtained by cooling…”
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Metabolic Risk Score in Heart Failure: Fuel for Thought? by Yoo, Edwin J., Shah, Svati H., Sharma, Kavita

“…[Display omitted]…”
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Inhibition of PI3K promotes dilation of human small airways in a rho kinase‐dependent manner by Koziol‐White, Cynthia J, Yoo, Edwin J, Cao, Gaoyuan, Zhang, Jie, Papanikolaou, Eleni, Pushkarsky, Ivan, Andrews, Adam, Himes, Blanca E, Damoiseaux, Robert D, Liggett, Stephen B, Di Carlo, Dino, Kurten, Richard C, Panettieri, Reynold A

“…Background and Purpose Asthma manifests as a heterogeneous syndrome characterized by airway obstruction, inflammation and hyperresponsiveness (AHR). Although…”
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Particle elasticity influences polymeric artificial antigen presenting cell effectiveness in vivo via CD8+ T cell activation, macrophage uptake, and the protein corona by Est-Witte, Savannah E., Shannon, Sydney R., Gong, Dennis H., Calabresi, Kaitlyn G., Harris, Jawaun J., Storm, Kaitlyn, Yoo, Edwin J., Isser, Ariel, Jani, Vivek P., Livingston, Natalie K., Omotoso, Mary O., Rhodes, Kelly, Ben-Akiva, Elana, Meyer, Randall A., Hsieh, Zoe T., Sidoli, Simone, Tzeng, Stephany Y., Schneck, Jonathan P., Green, Jordan J.

“…Adoptive cell therapy (ACT) is an immunotherapy strategy for cancer that has seen widespread clinical success. During ACT, patient-derived lymphocytes are…”
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Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3‐kinase‐mediated activation in a RhoA‐dependent manner by Yoo, Edwin J, Cao, Gaoyuan, Koziol‐White, Cynthia J, Ojiaku, Christie A, Sunder, Krishna, Jude, Joseph A, Michael, James V, Lam, Hong, Pushkarsky, Ivan, Damoiseaux, Robert, Di Carlo, Dino, Ahn, Kwangmi, An, Steven S, Penn, Raymond B, Panettieri, Reynold A

“…Background and Purpose PI3K‐dependent activation of Rho kinase (ROCK) is necessary for agonist‐induced human airway smooth muscle cell (HASMC) contraction, and…”
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Global Level Quantification of Histone Post-Translational Modifications in a 3D Cell Culture Model of Hepatic Tissue by Joseph-Chowdhury, Jazmine-Saskya N, Stransky, Stephanie, Graff, Sarah, Cutler, Ronald, Young, Dejauwne, Kim, Julie S, Madrid-Aliste, Carlos, Aguilan, Jennifer T, Nieves, Edward, Sun, Yan, Yoo, Edwin J, Sidoli, Simone

“…Flat cultures of mammalian cells are a widely used in vitro approach for understanding cell physiology, but this system is limited in modeling solid tissues…”
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Abstract 18916: Myocardial Proteomic Signatures in Human Heart Failure With Preserved Ejection Fraction by Jani, Vivek, Yoo, Edwin J, Kass, David A, Hahn, Virginia S

“…Abstract only Introduction: Heart Failure with Preserved Ejection Fraction (HFpEF) constitutes more than half of all heart failure but has few effective…”
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Metabolic Risk Score in Heart Failure by Yoo, Edwin J., Shah, Svati H., Sharma, Kavita

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Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction by Hahn, Virginia S., Petucci, Christopher, Kim, Min-Soo, Bedi, Kenneth C., Wang, Hanghang, Mishra, Sumita, Koleini, Navid, Yoo, Edwin J., Margulies, Kenneth B., Arany, Zoltan, Kelly, Daniel P., Kass, David A., Sharma, Kavita

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G[alpha]12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner by Yoo, Edwin J, Cao, Gaoyuan, Koziol-White, Cynthia J, Ojiaku, Christie A, Sunder, Krishna, Jude, Joseph A, Michael, James V, Lam, Hong, Pushkarsky, Ivan, Damoiseaux, Robert, Di Carlo, Dino, Ahn, Kwangmi, An, Steven S, Penn, Raymond B, Panettieri, Reynold A

“…Background and Purpose PI3K-dependent activation of Rho kinase (ROCK) is necessary for agonist-induced human airway smooth muscle cell (HASMC) contraction, and…”
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Gα 12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner by Yoo, Edwin J, Cao, Gaoyuan, Koziol-White, Cynthia J, Ojiaku, Christie A, Sunder, Krishna, Jude, Joseph A, Michael, James V, Lam, Hong, Pushkarsky, Ivan, Damoiseaux, Robert, Di Carlo, Dino, Ahn, Kwangmi, An, Steven S, Penn, Raymond B, Panettieri, Jr, Reynold A

“…PI3K-dependent activation of Rho kinase (ROCK) is necessary for agonist-induced human airway smooth muscle cell (HASMC) contraction, and inhibition of PI3K…”
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Transforming Growth Factor b1 Function in Airway Remodeling and Hyperresponsiveness: The Missing Link? by Ojiaku, Christie A, Yoo, Edwin J, Panettieri, Reynold A

“…The pathogenesis of asthma includes a complex interplay among airway inflammation, hyperresponsiveness, and remodeling. Current evidence suggests that airway…”
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Targeting Calcium Sensitization Mechanisms in Human Airway Smooth Muscle for Novel Bronchodilator Therapy in Asthma by Yoo, Edwin J

“…Asthma is characterized by airway hyperresponsiveness (AHR) and inflammation. Management of asthma involves controlling airway inflammation with inhaled…”
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