Search Results - "Yoo, Donghyuck"
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Molecularly Engineered Theranostic Nanoparticles for Thrombosed Vessels: H2O2‑Activatable Contrast-Enhanced Photoacoustic Imaging and Antithrombotic Therapy
Published in ACS nano (23-01-2018)“…A thrombus (blood clot), composed mainly of activated platelets and fibrin, obstructs arteries or veins, leading to various life-threatening diseases. Inspired…”
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Chemiluminescent and Antioxidant Micelles as Theranostic Agents for Hydrogen Peroxide Associated-Inflammatory Diseases
Published in Advanced functional materials (10-10-2012)“…Hydrogen peroxide (H2O2) is one of essential oxygen metabolites in living organisms, but is generated in large amounts during inflammatory responses…”
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Oligochitosan-stabilized photoluminescent gold nanoconstructs for optical bioimaging
Published in Biomaterials research (17-10-2017)“…Gold nanoclusters (AuNCs) are typically composed of several to tens of gold atoms which are stabilized with biomacromolecules such as bovine serum albumin…”
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Glutathione-Depleting Pro-Oxidant as a Selective Anticancer Therapeutic Agent
Published in ACS omega (30-06-2019)“…A main challenge in the development of anticancer drugs that eradicate cancer cells specifically with minimal toxicity to normal cells is to identify the…”
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Ultrasound imaging and on-demand therapy of peripheral arterial diseases using H2O2-Activated bubble generating anti-inflammatory polymer particles
Published in Biomaterials (01-10-2018)“…Muscles of peripheral artery disease (PAD) patients are under oxidative stress associated with a significantly elevated level of reactive oxygen species (ROS)…”
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Dual Stimuli-Activatable Oxidative Stress Amplifying Agent as a Hybrid Anticancer Prodrug
Published in Bioconjugate chemistry (19-04-2017)“…Compared to normal cells, cancer cells have a higher level of reactive oxygen species (ROS) due to aberrant metabolism and disruption of redox homeostasis…”
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Acid-activatable oxidative stress-inducing polysaccharide nanoparticles for anticancer therapy
Published in Journal of controlled release (10-01-2018)“…Drug delivery systems have been extensively developed to enhance the therapeutic efficacy of drugs by altering their pharmacokinetics and biodistribution…”
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Dual Imaging-Guided Oxidative–Photothermal Combination Anticancer Therapeutics
Published in ACS applied materials & interfaces (28-11-2018)“…Heme oxygenase-1 (HO-1) is a stress-response protein with potent cytoprotective and antioxidant activity, and its expression in cancer cells is enhanced in…”
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Antioxidant polymeric nanoparticles as novel therapeutics for airway inflammatory diseases
Published in International journal of pharmaceutics (25-06-2013)“…Successful pulmonary drug delivery requires polymeric drug delivery systems which have excellent biocompatibility and fast degradation rates, when frequent…”
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H2O2-responsive antioxidant polymeric nanoparticles as therapeutic agents for peripheral arterial disease
Published in International journal of pharmaceutics (25-09-2016)“…[Display omitted] Peripheral artery disease (PAD) is a common circulatory disorder in which narrowed arteries limit blood flow to the lower extremity and…”
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Hydrogen peroxide-activatable polymeric prodrug of curcumin for ultrasound imaging and therapy of acute liver failure
Published in Nanomedicine (01-02-2019)“…Curcumin is a major active phenolic component of turmeric and has gained great attention in pharmaceutics due to its potent antioxidant, anti-inflammatory and…”
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Porous antioxidant polymer microparticles as therapeutic systems for the airway inflammatory diseases
Published in Journal of controlled release (10-07-2016)“…Inhaling steroidal anti-inflammatory drugs is the most common treatment for airway inflammatory diseases such as asthma. However, frequent steroid…”
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H 2 O 2 -responsive antioxidant polymeric nanoparticles as therapeutic agents for peripheral arterial disease
Published in International journal of pharmaceutics (01-09-2016)Get full text
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Molecularly Engineered Theranostic Nanoparticles for Thrombosed Vessels: H 2 O 2 -Activatable Contrast-Enhanced Photoacoustic Imaging and Antithrombotic Therapy
Published in ACS nano (23-01-2018)“…A thrombus (blood clot), composed mainly of activated platelets and fibrin, obstructs arteries or veins, leading to various life-threatening diseases. Inspired…”
Get full text
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15
Enhanced cytosolic drug delivery using fully biodegradable poly(amino oxalate) particles
Published in Journal of controlled release (10-06-2011)“…Rapid endosomal escape of drug carriers is crucial to enhancing the efficacy of their macromolecular payload, especially proteins that are susceptible to…”
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Fully biodegradable and cationic poly(amino oxalate) particles for the treatment of acetaminophen-induced acute liver failure
Published in International journal of pharmaceutics (15-09-2012)“…Acute inflammatory diseases are one of major causes of death in the world and there is great need for developing drug delivery systems that can target drugs to…”
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17
Ultrasound imaging and on-demand therapy of peripheral arterial diseases using H 2 O 2 -Activated bubble generating anti-inflammatory polymer particles
Published in Biomaterials (01-10-2018)“…Muscles of peripheral artery disease (PAD) patients are under oxidative stress associated with a significantly elevated level of reactive oxygen species (ROS)…”
Get full text
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