Search Results - "Yonkus, Jennifer A"

Surgical Management of Metastatic Gastrointestinal Stromal Tumors by Yonkus, Jennifer A., Alva-Ruiz, Roberto, Grotz, Travis E.

“…Opinion statement Treatment with the tyrosine kinase inhibitor (TKI), imatinib is the standard first-line treatment for metastatic gastrointestinal stromal…”
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YAP‐TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing therapeutic escape by Alva‐Ruiz, Roberto, Watkins, Ryan D., Tomlinson, Jennifer L., Yonkus, Jennifer A., Abdelrahman, Amro M., Conboy, Caitlin B., Jessen, Erik, Werneburg, Nathan W., Kuipers, Hendrien, Sample, Jack W., Gores, Gregory J., Ilyas, Sumera I., Truty, Mark J., Smoot, Rory L.

“…Cholangiocarcinoma (CCA) is a highly aggressive form of liver cancer and is an increasing cause of cancer‐related death worldwide. Despite its increasing…”
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An expeditious and precise method for diameter reduction of venous aneurysm causing arteriovenous fistula steal syndrome by Yonkus, Jennifer A., Tallarita, Tiziano, Sen, Indrani, Beckermann, Jason, Carmody, Thomas

“…Clinically significant dialysis access steal syndrome occurs in 1% to 8% of patients. In the present report, we describe an innovative, hybrid option for…”
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Optimizing Nanopore Sequencing for Rapid Detection of Microbial Species and Antimicrobial Resistance in Patients at Risk of Surgical Site Infections by Whittle, Emma, Yonkus, Jennifer A, Jeraldo, Patricio, Alva-Ruiz, Roberto, Nelson, Heidi, Kendrick, Michael L, Grys, Thomas E, Patel, Robin, Truty, Mark J, Chia, Nicholas

“…Surgical site infections (SSI) are a significant burden to patients and health care systems. We evaluated the use of Nanopore sequencing (NS) to rapidly detect…”
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In vivo label-free optical signatures of chemotherapy response in human pancreatic ductal adenocarcinoma patient-derived xenografts by Park, Jaena, Sorrells, Janet E., Chaney, Eric J., Abdelrahman, Amro M., Yonkus, Jennifer A., Leiting, Jennifer L., Nelson, Heidi, Harrington, Jonathan J., Aksamitiene, Edita, Marjanovic, Marina, Groves, Peter D., Bushell, Colleen, Truty, Mark J., Boppart, Stephen A.

“…Pancreatic cancer is a devastating disease often detected at later stages, necessitating swift and effective chemotherapy treatment. However, chemoresistance…”
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SHP2 inhibition enhances Yes-associated protein–mediated liver regeneration in murine partial hepatectomy models by Watkins, Ryan D., Buckarma, EeeLN H., Tomlinson, Jennifer L., McCabe, Chantal E., Yonkus, Jennifer A., Werneburg, Nathan W., Bayer, Rachel L., Starlinger, Patrick P., Robertson, Keith D., Wang, Chen, Gores, Gregory J., Smoot, Rory L.

“…Disrupted liver regeneration following hepatectomy represents an “undruggable” clinical challenge associated with poor patient outcomes. Yes-associated protein…”
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Anterior Axillary Arch: An Anatomic Variant Every Surgeon Operating in the Axilla Should Be Aware of by Yonkus, Jennifer A., Jakub, James W.

“…Anterior axillary arch (AAA) is a slip of latissimus dorsi muscle, of variable thickness, which crosses anterior to the axillary vessels and brachial plexus…”
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Yield of Staging Laparoscopy for Pancreatic Cancer in the Modern Era: Analysis of More than 1,000 Consecutive Patients by Gudmundsdottir, Hallbera, Yonkus, Jennifer A, Alva-Ruiz, Roberto, Kendrick, Michael L, Smoot, Rory L, Warner, Susanne G, Starlinger, Patrick, Thiels, Cornelius A, Nagorney, David M, Cleary, Sean P, Grotz, Travis E, Truty, Mark J

“…Accurate staging prior to resection of pancreatic ductal adenocarcinoma (PDAC) is imperative to avoid unnecessary operative morbidity and oncologic futility in…”
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Neoadjuvant Chemotherapy Switch in Borderline Resectable/Locally Advanced Pancreatic Cancer by Alva-Ruiz, Roberto, Yohanathan, Lavanya, Yonkus, Jennifer A., Abdelrahman, Amro M., Gregory, Lindsey A., Halfdanarson, Thorvadur R., Mahipal, Amit, McWilliams, Robert R., Ma, Wen Wee, Hallemeier, Christopher L., Graham, Rondell P., Grotz, Travis E., Smoot, Rory L., Cleary, Sean P., Nagorney, David M., Kendrick, Michael L., Truty, Mark J.

“…Background Neoadjuvant chemotherapy (NAC) is an integral part of preoperative treatment for patients with borderline resectable/locally advanced (BR/LA)…”
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Outcomes of Visceral Arterial Interposition Graft Reconstruction for Locally Advanced Pancreatic Cancer by Yonkus, Jennifer A, Alva-Ruiz, Roberto, Colglazier, Jill J, Kendrick, Michael L, Kalra, Manju, Rasmussen, Todd E, Demartino, Randall D, Bower, Thomas C, Truty, Mark J, Mendes, Bernardo C

“…The aim of this study is to determine perioperative outcomes and the patency of interposition conduits for visceral arterial reconstruction in this setting…”
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Oncologic Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Highly Selected Patients with Metastatic Pancreatic Ductal Adenocarcinoma by Gudmundsdottir, Hallbera, Yonkus, Jennifer A., Thiels, Cornelius A., Warner, Susanne G., Cleary, Sean P., Kendrick, Michael L., Truty, Mark J., Grotz, Travis E.

“…Background Peritoneal metastases (PM) from pancreatic ductal adenocarcinoma (PDAC) are currently treated with palliative systemic chemotherapy alone, with…”
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The effect of pre-operative diagnosis on patient reported outcomes in patients undergoing colorectal operations: A prospective study by Yonkus, Jennifer A., Thiels, Cornelius A., Skaran, Pamela, Mathis, Kellie L., Bingener, Juliane

“…Patient Reported Outcomes (PROs) capture peri-operative fatigue, pain, and quality of life and influence outcomes in gastrointestinal surgery. We compared…”
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ASO Visual Abstract: Oncologic Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Highly Selected Patients with Metastatic Pancreatic Ductal Adenocarcinoma by Gudmundsdottir, Hallbera, Yonkus, Jennifer A., Thiels, Cornelius A., Warner, Susanne G., Cleary, Sean P., Kendrick, Michael L., Truty, Mark J., Grotz, Travis E.

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Cytoreduction with Hyperthermic Intraperitoneal Chemoperfusion for Pancreatic Cancer with Low-Volume Peritoneal Metastasis: Results from a Prospective Pilot Study by Grotz, Travis E., Yonkus, Jennifer A., Thiels, Cornelius A., Warner, Susanne G., McWilliams, Robert R., Mahipal, Amit, Bekaii-Saab, Tanios S., Cleary, Sean P., Kendrick, Michael L., Truty, Mark J.

“…Introduction Resection of oligometastatic pancreatic ductal adenocarcinoma (PDAC) has historically been ineffective, however modern systemic chemotherapy has…”
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ASO Visual Abstract: Cytoreduction with Hyperthermic Intraperitoneal Chemoperfusion for Pancreatic Cancer with Low-Volume Peritoneal Metastasis—Results from a Prospective Pilot Study by Grotz, Travis E., Yonkus, Jennifer A., Thiels, Cornelius A., Warner, Susanne G., McWilliams, Robert, Mahipal, Amit, Bekaii-Saab, Tanios S., Cleary, Sean P., Kendrick, Michael L., Truty, Mark J.

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“Answers in hours”: A prospective clinical study using nanopore sequencing for bile duct cultures by Yonkus, Jennifer A., Whittle, Emma, Alva-Ruiz, Roberto, Abdelrahman, Amro M., Horsman, Susan E., Suh, Gina A., Cunningham, Scott A., Nelson, Heidi, Grotz, Travis E., Smoot, Rory L., Cleary, Sean P., Nagorney, David M., Kendrick, Michael L., Patel, Robin, Truty, Mark J., Chia, Nicholas

“…Surgical site infection is a major source of morbidity in patients undergoing pancreatic head resection and is often from organisms in intraoperative bile duct…”
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LCK inhibition downregulates YAP activity and is therapeutic in patient-derived models of cholangiocarcinoma by Conboy, Caitlin B., Yonkus, Jennifer A., Buckarma, EeeLN H., Mun, Dong-Gi, Werneburg, Nathan W., Watkins, Ryan D., Alva-Ruiz, Roberto, Tomlinson, Jennifer L., Guo, Yi, Wang, Juan, O’Brien, Daniel, McCabe, Chantal E., Jessen, Erik, Graham, Rondell P., Buijsman, Rogier C., Vu, Diep, de Man, Jos, Ilyas, Sumera I., Truty, Mark J., Borad, Mitesh, Pandey, Akhilesh, Gores, Gregory J., Smoot, Rory L.

“…There is an unmet need to develop novel, effective medical therapies for cholangiocarcinoma (CCA). The Hippo pathway effector, Yes-associated protein (YAP), is…”
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FDG-PET Predicts Neoadjuvant Therapy Response and Survival in Borderline Resectable/Locally Advanced Pancreatic Adenocarcinoma by Abdelrahman, Amro M, Goenka, Ajit H, Alva-Ruiz, Roberto, Yonkus, Jennifer A, Leiting, Jennifer L, Graham, Rondell P, Merrell, Kenneth W, Thiels, Cornelius A, Hallemeier, Christopher L, Warner, Susanne G, Haddock, Michael G, Grotz, Travis E, Tran, Nguyen H, Smoot, Rory L, Ma, Wen Wee, Cleary, Sean P, McWilliams, Robert R, Nagorney, David M, Halfdanarson, Thorvardur R, Kendrick, Michael L, Truty, Mark J

“…Neoadjuvant therapy (NAT) is used in borderline resectable/locally advanced (BR/LA) pancreatic ductal adenocarcinoma (PDAC). Anatomic imaging (CT/MRI) poorly…”
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Intraoperative bile duct cultures in patients undergoing pancreatic head resection: Prospective comparison of bile duct swab versus bile duct aspiration by Yonkus, Jennifer A., Alva-Ruiz, Roberto, Abdelrahman, Amro M., Horsman, Susan E., Cunningham, Scott A., Grotz, Travis E., Smoot, Rory L., Cleary, Sean P., Nagorney, David M., Kendrick, Michael L., Truty, Mark J.

“…Postoperative surgical site infection is a major source of morbidity after pancreatic head resections, and data suggest bacterobilia as a leading cause. Some…”
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Re-resection of Microscopically Positive Margins Found on Intraoperative Frozen Section Analysis Does Not Result in a Survival Benefit in Patients Undergoing Surgery and Intraoperative Radiation Therapy for Locally Recurrent Rectal Cancer by Ansell, James, Perry, William R.G., Mathis, Kellie L., Grass, Fabian, Yonkus, Jennifer A., Hallemeier, Christopher L., Haddock, Michael G., Graham, Rondell P., Merchea, Amit, Colibaseanu, Dorin T., Mishra, Nitin, Kelley, Scott R., Larson, David W., Dozois, Eric J.

“…Intraoperative frozen-section analysis provides real-time margin resection status that can guide intraoperative decisions made by the surgeon and radiation…”
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