Search Results - "Yongbing, Sun"

The Quantification of Paclitaxel and Its Two Major Metabolites in Biological Samples by HPLC-MS/MS and Its Application in a Pharmacokinetic and Tumor Distribution Study in Xenograft Nude Mouse by Huang, Haijin, Huang, Haolin, Sun, Yongbing, Liu, Qian

“…A rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed for the quantification of Paclitaxel…”
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Cancer nanotechnology: Enhancing tumor cell response to chemotherapy for hepatocellular carcinoma therapy by Sun, Yongbing, Ma, Wen, Yang, Yuanyuan, He, Mengxue, Li, Aimin, Bai, Lei, Yu, Bin, Yu, Zhiqiang

“…Hepatocellular carcinoma (HCC) is one of the deadliest cancers due to its complexities, reoccurrence after surgical resection, metastasis and heterogeneity. In…”
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The mediating effect of psychological resilience between social support and anxiety/depression in people living with HIV/AIDS-a study from China by Sun, Yongbing, Song, Bing, Zhen, Cheng, Zhang, Chao, Cheng, Juan, Jiang, Tianjun

“…Objective To understand the relationship between psychological resilience in social support and anxiety/depression in people living with HIV/AIDS and to verify…”
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Cathepsin B-responsive nanodrug delivery systems for precise diagnosis and targeted therapy of malignant tumors by Li, Yanan, Mei, Ting, Han, Shupeng, Han, Tao, Sun, Yongbing, Zhang, Hui, An, Feifei

“…Cathepsin B-responsive multifunctional nanosized drug delivery systems (nanoDDS) enabling imaging and drug delivery have attracted extensive research interest…”
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Nanocrystal-Loaded Micelles for the Enhanced In Vivo Circulation of Docetaxel by Cheng, Meng, Liu, Qiaoming, Gan, Tiantian, Fang, Yuanying, Yue, Pengfei, Sun, Yongbing, Jin, Yi, Feng, Jianfang, Tu, Liangxing

“…Prolonging in vivo circulation has proved to be an efficient route for enhancing the therapeutic effect of rapidly metabolized drugs. In this study, we aimed…”
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Application of TBSS-based machine learning models in the diagnosis of pediatric autism by He, Xiongpeng, Zhao, Xin, Sun, Yongbing, Geng, Pengfei, Zhang, Xiaoan

“…To explore the microstructural changes of white matter in children with pediatric autism by using diffusion kurtosis imaging (DKI), and evaluate whether the…”
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Protease-triggered bioresponsive drug delivery for the targeted theranostics of malignancy by Li, Yanan, Zhang, Cangang, Li, Guo, Deng, Guowei, Zhang, Hui, Sun, Yongbing, An, Feifei

“…Proteases have a fundamental role in maintaining physiological homeostasis, but their dysregulation results in severe activity imbalance and pathological…”
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Pre-incubated with BSA-complexed free fatty acids alters ER stress/autophagic gene expression by carboxylated multi-walled carbon nanotube exposure in THP-1 macrophages by Yang, Qianyu, Wang, Maolin, Sun, Yongbing, Peng, Shengming, Ding, Yanhuai, Cao, Yi

“…Pre-incubation with BSA-complexed free fatty acids influenced the colloidal aspects of carboxylated multi-walled carbon nanotubes (c-MWCNTs), and altered…”
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Magnetic resonance imaging-guided and targeted theranostics of colorectal cancer by Li, Yanan, Xin, Jingqi, Sun, Yongbing, Han, Tao, Zhang, Hui, An, Feifei

“…Colorectal cancer (CRC) is the most common gastrointestinal tract cancer worldwide and is associated with high morbidity and mortality. The development of…”
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Association between total cholesterol and lumbar bone density in Chinese: a study of physical examination data from 2018 to 2023 by Sun, Yongbing, Qi, Xin, Lin, Xinbei, Zhou, Yang, Lv, Xue, Zhou, Jing, Li, Zhonglin, Wu, Xiaoling, Zou, Zhi, Li, Yongli, Li, Hao

“…Abstract Background The impact of total cholesterol (TC) on lumbar bone mineral density (BMD) is a topic of interest. However, empirical evidence on this…”
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A validated high‐performance liquid chromatography‐tandem mass spectrometry method for simultaneous determination of irinotecan and two major metabolites in rat plasma: Application for the pharmacokinetics study by Liangzhu, Jiang, Nan, Gu, Yuzhi, Peng, Yuxin, Liao, Limin, Zhou, Yongbing, Sun

“…A high‐performance liquid chromatography‐tandem mass spectrometry method has been developed for the determination of irinotecan, 7‐ethyl‐10‐hydroxycamptothecin…”
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Nonlinear association between atherogenic index of plasma and type 2 diabetes mellitus in overweight and obesity patients: evidence from Chinese medical examination data by Sun, Yongbing, Li, Fengli, Zhou, Yang, Liu, Ao, Lin, Xinbei, Zou, Zhi, Lv, Xue, Zhou, Jing, Li, Zhonglin, Wu, Xiaoling, Dou, Shewei, Zhang, Michael, Zhu, Jiadong, Chen, Yalong, Xiao, Xinguang, Hu, Yangxi, Li, Hao, Li, Yongli

“…The atherogenic index of plasma (AIP) is closely associated with the onset of diabetes, with obesity being a significant risk factor for type 2 diabetes…”
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Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study by Sun, Yongbing, Qi, Xin, Wang, Xuan, Lin, Xinbei, Zhou, Yang, Du, Yawei, Liu, Ao, Lv, Xue, Zhou, Jing, Li, Zhonglin, Wu, Xiaoling, Zou, Zhi, Zhang, Michael, Zhu, Jiadong, Shang, Feifei, Li, Yongli, Li, Hao

“…The association between lipid and bone metabolism, particularly the role of high-density lipoprotein cholesterol (HDL-C) in regulating bone mineral density…”
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A Comparative Assessment of MR BI-RADS 4 Breast Lesions With Kaiser Score and Apparent Diffusion Coefficient Value by Meng, Lingsong, Zhao, Xin, Lu, Lin, Xing, Qingna, Wang, Kaiyu, Guo, Yafei, Shang, Honglei, Chen, Yan, Huang, Mengyue, Sun, Yongbing, Zhang, Xiaoan

“…To investigate the diagnostic performance of the Kaiser score and apparent diffusion coefficient (ADC) to differentiate Breast Imaging Reporting and Data…”
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Nonlinear association between the triglyceride-glucose index and diabetes mellitus in overweight and obese individuals: a cross-sectional retrospective analysis by Sun, Yongbing, Gu, Yuang, Zhou, Yang, Liu, Ao, Lin, Xinbei, Wang, Xuan, Du, Yawei, Lv, Xue, Zhou, Jing, Li, Zhonglin, Wu, Xiaoling, Zou, Zhi, Dou, Shewei, Zhang, Michael, Zhu, Jiadong, Shang, Feifei, Li, Fengli, Hu, Yangxi, Li, Hao, Li, Yongli

“…The triglyceride-glucose (TyG) index is linked to both the development and progression of diabetes, while obesity remains a significant risk factor for this…”
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High‐performance liquid chromatography‐tandem mass spectrometry method for determination of peramivir in rat plasma using the simple protein precipitation pretreatment by Ke, Xin, Nan, Gu, Lili, Wan, Jiaai, Zhou, Ziqian, Huang, Liangxing, Tu, Qi, Zhang, Heyun, Nie, Yongbing, Sun

“…A high‐performance liquid chromatography‐tandem mass spectrometry method has been developed for the determination of peramivir in rat plasma in the present…”
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Prodrug design targeting intestinal PepT1 for improved oral absorption: design and performance by Zhang, Youxi, Sun, Jin, Sun, Yongbing, Wang, Yongjun, He, Zhonggui

“…Oligopeptide transporter 1 (PepT1) plays an essential role in the oral absorption of di-and tripeptides from the digestion of ingested protein. PepT1 has…”
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PEPT1-mediated prodrug strategy for oral delivery of peramivir by Sun, Yongbing, Gan, Wei, Lei, Mingdao, Jiang, Wei, Cheng, Meng, He, Junwei, Sun, Qi, Liu, Wan, Hu, Lvjiang, Jin, Yi

“…Peramivir was a novel and highly potent neuraminidase (NA) inhibitor for the treatment of influenza A and B. However, it exhibited a very low oral…”
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A Carrier-Mediated Prodrug Approach To Improve the Oral Absorption of Antileukemic Drug Decitabine by Zhang, Youxi, Sun, Jin, Gao, Yikun, Jin, Ling, Xu, Youjun, Lian, He, Sun, Yongbing, Sun, Yinghua, Liu, Jianyu, Fan, Rui, Zhang, Tianhong, He, Zhonggui

“…Decitabine (5-aza-2′-deoxycytidine, DAC) is a novel DNA methyltransferase (DNMT) inhibitor for the treatment of myelodysplastic syndrome, acute and chronic…”
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Bifunctional Peptidomimetic Prodrugs of Didanosine for Improved Intestinal Permeability and Enhanced Acidic Stability: Synthesis, Transepithelial Transport, Chemical Stability and Pharmacokinetics by Yan, Zhongtian, Sun, Jin, Chang, Yannan, Liu, Yanhua, Fu, Qiang, Xu, Youjun, Sun, Yongbing, Pu, Xiaohui, Zhang, Youxi, Jing, Yongkui, Yin, Shiliang, Zhu, Meng, Wang, Yongjun, He, Zhonggui

“…Five peptidomimetic prodrugs of didanosine (DDI) were synthesized and designed to improve bioavailability of DDI following oral administration via targeting…”
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