Search Results - "Yong-Wook Baek"
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Exposure to environmental chemicals among Korean adults-updates from the second Korean National Environmental Health Survey (2012–2014)
Published in International journal of hygiene and environmental health (01-03-2017)“…National biomonitoring program can offer solid scientific evidence on exposure profiles of environmental chemicals at a national level, and provide a snapshot…”
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Biodistribution and respiratory toxicity of chloromethylisothiazolinone/methylisothiazolinone following intranasal and intratracheal administration
Published in Environment international (01-12-2022)“…[Display omitted] •The biodistribution of CMIT/MIT was assessed using a 14C-labeled radiotracer.•After exposure via the inhalation routes, CMIT/MIT is rapidly…”
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Longitudinal long term follow up investigation on the carcinogenic impact of polyhexamethylene guanidine phosphate in rat models
Published in Scientific reports (26-03-2024)“…Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our…”
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Assay-dependent effect of silver nanoparticles to Escherichia coli and Bacillus subtilis
Published in Applied microbiology and biotechnology (01-12-2011)“…We assess the microbial assay-dependent effect of AgNP on gram-negative Escherichia coli and gram-positive Bacillus subtilis . The experiment was conducted via…”
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Gene expression related to lung cancer altered by PHMG-p treatment in PBTE cells
Published in Molecular & cellular toxicology (2023)“…Background Humidifier disinfectants (HDs), including polyhexamethylene guanidine phosphate (PHMG-p), are commonly used in Korea to prevent microbial growth…”
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Evaluating the comparative MT1B, MT1F, MT1G, and MT1H expression in human pulmonary alveolar epithelial cells treated with polyhexamethylene guanidine-phosphate, chloromethylisothiazolinone/methylisothiazolinone, oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride, benzalkonium chloride, and sodium dichloroisocyanurate
Published in Molecular & cellular toxicology (2023)“…Background We previously reported the increase in expression of metallothionein1 (MT1) B, MT1F, MT1G, and MT1H after exposure to polyhexamethylene guanidine…”
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Analysis of lung cancer-related genetic changes in long-term and low-dose polyhexamethylene guanidine phosphate (PHMG-p) treated human pulmonary alveolar epithelial cells
Published in BMC pharmacology & toxicology (30-03-2022)“…Lung injury elicited by respiratory exposure to humidifier disinfectants (HDs) is known as HD-associated lung injury (HDLI). Current elucidation of the…”
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Flexible-Imaging-Fiber-Guided Intratracheal Intubation in Rodents
Published in Applied sciences (01-04-2023)“…Although experiments on intratracheal intubation for animals are essential for research, it remains challenging. This study aimed to validate an animal model…”
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Evidence integration on health damage for humidifier disinfectant exposure and legal presumption of causation
Published in Epidemiology and health (24-10-2023)“…Inhalation exposure to humidifier disinfectants has resulted to various types of health damages in Korea. To determine the epidemiological correlation…”
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Microbial toxicity of metal oxide nanoparticles (CuO, NiO, ZnO, and Sb2O3) to Escherichia coli, Bacillus subtilis, and Streptococcus aureus
Published in The Science of the total environment (15-03-2011)“…In this study, the microbial toxicities of metal oxide nanoparticles were evaluated for Escherichia coli, Bacillus subtilis, and Streptococcus aureus in…”
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MTF1 Is Essential for the Expression of MT1B, MT1F, MT1G, and MT1H Induced by PHMG, but Not CMIT, in the Human Pulmonary Alveolar Epithelial Cells
Published in Toxics (Basel) (29-08-2021)“…The inhalation of humidifier disinfectants (HDs) is linked to HD-associated lung injury (HDLI). Polyhexamethylene guanidine (PHMG) is significantly involved in…”
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A Novel Small-Molecule Inhibitor of Endosomal TLRs Reduces Inflammation and Alleviates Autoimmune Disease Symptoms in Murine Models
Published in Cells (Basel, Switzerland) (09-07-2020)“…Toll-like receptors (TLRs) play a fundamental role in the inflammatory response against invading pathogens. However, the dysregulation of TLR-signaling…”
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Evidence integration on health damage for humidifier disinfectant exposure and legal presumption of causation
Published in Epidemiology and health (01-01-2023)Get full text
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Investigation of disinfectants for foot-and-mouth disease in the Republic of Korea
Published in Journal of infection and public health (01-10-2013)“…Summary Disinfectants for foot-and-mouth disease were sprayed on livestock barns and roads from early February to May 2011. Although 90% of the disinfectant…”
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Effects of stabilizer magnesium nirate on CMIT/MIT-induced respiratory toxicity
Published in Toxicological research (Seoul) (01-07-2023)“…Despite a humidifier disinfectant (HD) product containing chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) with approximately 22% magnesium…”
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Ecological effects of soil antimony on the crop plant growth and earthworm activity
Published in Environmental earth sciences (01-01-2014)“…High levels of antimony have been frequently detected in some industrial sites. This study evaluated the adverse effects of antimony (Sb) on the…”
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Hematotoxic Effect of Respiratory Exposure to PHMG-p and Its Integrated Genetic Analysis
Published in Toxics (Basel) (01-11-2022)“…Polyhexamethylene guanidine phosphate (PHMG-p), the main ingredient of humidifier disinfectants, circulates systemically through the lungs; however, its…”
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Assessment of toxic heavy metals in urban lake sediments as related to urban stressor and bioavailability
Published in Environmental monitoring and assessment (01-12-2010)“…A suite of heavy metals was monitored at sediments and overlying water in three urban lakes located in Seoul, Korea during spring season 2006. Metals measured…”
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환경 중 1,2-Benzisothiazol-3-one에 대한 초기 생태위해성 평가
Published in Daehan hwan'gyeong gonghag hoeji (2013)“…In this study, physico-chemical properties and environmental fate were investigated and ecotoxicity tests using fish, daphnia and algae were conducted for an…”
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The effect of biocide chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) mixture on C2C12 muscle cell damage attributed to mitochondrial reactive oxygen species overproduction and autophagy activation
Published in Journal of Toxicology and Environmental Health, Part A (24-10-2024)“…The mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one (CMIT/MIT) is a biocide widely used as a preservative in various…”
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