Search Results - "Yong, Minghan"

Cyclophosphamide bioactivation pharmacogenetics in breast cancer patients by Helsby, Nuala, Yong, Minghan, Burns, Kathryn, Findlay, Michael, Porter, David

“…Purpose Genetic variation in the activation of the prodrug cyclophosphamide (CP) by cytochrome P450 (CYP) enzymes has been shown to influence outcomes…”
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Intracellular activation of 4-hydroxycyclophosphamide into a DNA-alkylating agent in human leucocytes by Yong, Minghan, Burns, Kathryn Elisa, de Zoysa, Janak, Helsby, Nuala Ann

“…1.The conversion of the cyclophosphamide intermediate metabolite 4-hydroxycyclophosphamide (4-OHCP) to the final cytotoxic metabolite phosphoramide mustard…”
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