Search Results - "Yoneshiro, Takeshi"

Brown Adipose Tissue, Diet-Induced Thermogenesis, and Thermogenic Food Ingredients: From Mice to Men by Saito, Masayuki, Matsushita, Mami, Yoneshiro, Takeshi, Okamatsu-Ogura, Yuko

“…Since the recent rediscovery of brown adipose tissue (BAT) in adult humans, this thermogenic tissue has been attracting increasing interest. The inverse…”
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Brown fat thermogenesis and branched-chain amino acids in metabolic disease by Brown, Zachary, Yoneshiro, Takeshi

“…Since the 1960s, researchers have recognized an association between elevated plasma branched chain amino acids (BCAA) and metabolic disease, including type 2…”
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Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans by Saito, Masayuki, Yoneshiro, Takeshi

“…Capsaicin and its nonpungent analog (capsinoids) are known to be food ingredients that increase energy expenditure and decrease body fat. This article reviews…”
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Activation and recruitment of brown adipose tissue as anti-obesity regimens in humans by Yoneshiro, Takeshi, Saito, Masayuki

“…Brown adipose tissue (BAT) is the site of sympathetically activated adaptive thermogenesis during cold exposure and after hyperphagia, thereby controlling…”
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Recruited brown adipose tissue as an antiobesity agent in humans by Yoneshiro, Takeshi, Aita, Sayuri, Matsushita, Mami, Kayahara, Takashi, Kameya, Toshimitsu, Kawai, Yuko, Iwanaga, Toshihiko, Saito, Masayuki

“…Brown adipose tissue (BAT) burns fat to produce heat when the body is exposed to cold and plays a role in energy metabolism. Using fluorodeoxyglucose-positron…”
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Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism by Lu, Xiaodan, Altshuler-Keylin, Svetlana, Wang, Qiang, Chen, Yong, Henrique Sponton, Carlos, Ikeda, Kenji, Maretich, Pema, Yoneshiro, Takeshi, Kajimura, Shingo

“…Beige adipocytes are an inducible form of mitochondria-enriched thermogenic adipocytes that emerge in response to external stimuli, such as chronic cold…”
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Thermal stress induces glycolytic beige fat formation via a myogenic state by Chen, Yong, Ikeda, Kenji, Yoneshiro, Takeshi, Scaramozza, Annarita, Tajima, Kazuki, Wang, Qiang, Kim, Kyeongkyu, Shinoda, Kosaku, Sponton, Carlos Henrique, Brown, Zachary, Brack, Andrew, Kajimura, Shingo

“…Environmental cues profoundly affect cellular plasticity in multicellular organisms. For instance, exercise promotes a glycolytic-to-oxidative fibre-type…”
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BCAA catabolism in brown fat controls energy homeostasis through SLC25A44 by Yoneshiro, Takeshi, Wang, Qiang, Tajima, Kazuki, Matsushita, Mami, Maki, Hiroko, Igarashi, Kaori, Dai, Zhipeng, White, Phillip J., McGarrah, Robert W., Ilkayeva, Olga R., Deleye, Yann, Oguri, Yasuo, Kuroda, Mito, Ikeda, Kenji, Li, Huixia, Ueno, Ayano, Ohishi, Maki, Ishikawa, Takamasa, Kim, Kyeongkyu, Chen, Yong, Sponton, Carlos Henrique, Pradhan, Rachana N., Majd, Homa, Greiner, Vanille Juliette, Yoneshiro, Momoko, Brown, Zachary, Chondronikola, Maria, Takahashi, Haruya, Goto, Tsuyoshi, Kawada, Teruo, Sidossis, Labros, Szoka, Francis C., McManus, Michael T., Saito, Masayuki, Soga, Tomoyoshi, Kajimura, Shingo

“…Branched-chain amino acid (BCAA; valine, leucine and isoleucine) supplementation is often beneficial to energy expenditure; however, increased…”
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Brown Adipose Tissue, Whole-Body Energy Expenditure, and Thermogenesis in Healthy Adult Men by Yoneshiro, Takeshi, Aita, Sayuri, Matsushita, Mami, Kameya, Toshimitsu, Nakada, Kunihiro, Kawai, Yuko, Saito, Masayuki

“…Brown adipose tissue (BAT) can be identified by 18F‐fluorodeoxyglucose (FDG)‐positron emission tomography (PET) in adult humans. Thirteen healthy male…”
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Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart by Walejko, Jacquelyn M., Christopher, Bridgette A., Crown, Scott B., Zhang, Guo-Fang, Pickar-Oliver, Adrian, Yoneshiro, Takeshi, Foster, Matthew W., Page, Stephani, van Vliet, Stephan, Ilkayeva, Olga, Muehlbauer, Michael J., Carson, Matthew W., Brozinick, Joseph T., Hammond, Craig D., Gimeno, Ruth E., Moseley, M. Arthur, Kajimura, Shingo, Gersbach, Charles A., Newgard, Christopher B., White, Phillip J., McGarrah, Robert W.

“…Branched-chain amino acids (BCAA) and their cognate α-ketoacids (BCKA) are elevated in an array of cardiometabolic diseases. Here we demonstrate that the major…”
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Accumulation of succinate controls activation of adipose tissue thermogenesis by Mills, Evanna L., Pierce, Kerry A., Jedrychowski, Mark P., Garrity, Ryan, Winther, Sally, Vidoni, Sara, Yoneshiro, Takeshi, Spinelli, Jessica B., Lu, Gina Z., Kazak, Lawrence, Banks, Alexander S., Haigis, Marcia C., Kajimura, Shingo, Murphy, Michael P., Gygi, Steven P., Clish, Clary B., Chouchani, Edward T.

“…Thermogenesis by brown and beige adipose tissue, which requires activation by external stimuli, can counter metabolic disease 1 . Thermogenic respiration is…”
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Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis by Tajima, Kazuki, Ikeda, Kenji, Tanabe, Yuji, Thomson, Ella A., Yoneshiro, Takeshi, Oguri, Yasuo, Ferro, Marc D., Poon, Ada S. Y., Kajimura, Shingo

“…Cold stimuli and the subsequent activation of β-adrenergic receptor (β-AR) potently stimulate adipose tissue thermogenesis and increase whole-body energy…”
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Age-Related Decrease in Cold-Activated Brown Adipose Tissue and Accumulation of Body Fat in Healthy Humans by Yoneshiro, Takeshi, Aita, Sayuri, Matsushita, Mami, Okamatsu‐Ogura, Yuko, Kameya, Toshimitsu, Kawai, Yuko, Miyagawa, Masao, Tsujisaki, Masayuki, Saito, Masayuki

“…Brown adipose tissue (BAT) can be identified by 18F‐fluorodeoxyglucose (FDG)‐positron emission tomography (PET) combined with X‐ray computed tomography (CT) in…”
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Activation and recruitment of brown adipose tissue by cold exposure and food ingredients in humans by Saito, Masayuki, Yoneshiro, Takeshi, Matsushita, Mami

“…Abstract Since the recent re-discovery of brown adipose tissue (BAT) in adult humans, this thermogenic tissue has attracted increasing interest. The inverse…”
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Tea catechin and caffeine activate brown adipose tissue and increase cold-induced thermogenic capacity in humans by Yoneshiro, Takeshi, Matsushita, Mami, Hibi, Masanobu, Tone, Hiroshi, Takeshita, Masao, Yasunaga, Koichi, Katsuragi, Yoshihisa, Kameya, Toshimitsu, Sugie, Hiroki, Saito, Masayuki

“…ABSTRACT Background: The thermogenic effects of green tea catechin have been repeatedly reported, but their mechanisms are poorly understood. Objective: The…”
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Transient receptor potential activated brown fat thermogenesis as a target of food ingredients for obesity management by Yoneshiro, Takeshi, Saito, Masayuki

“…PURPOSE OF REVIEWCold exposure activates brown adipose tissue (BAT), the major site of sympathetically activated nonshivering thermognenesis, via transient…”
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Post-translational control of beige fat biogenesis by PRDM16 stabilization by Wang, Qiang, Li, Huixia, Tajima, Kazuki, Verkerke, Anthony R. P., Taxin, Zachary H., Hou, Zhishuai, Cole, Joanne B., Li, Fei, Wong, Jake, Abe, Ichitaro, Pradhan, Rachana N., Yamamuro, Tadashi, Yoneshiro, Takeshi, Hirschhorn, Joel N., Kajimura, Shingo

“…Compelling evidence shows that brown and beige adipose tissue are protective against metabolic diseases 1 , 2 . PR domain-containing 16 (PRDM16) is a dominant…”
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Human brown adipose tissue assessed by simple, noninvasive near‐Infrared time‐resolved spectroscopy by Nirengi, Shinsuke, Yoneshiro, Takeshi, Sugie, Hiroki, Saito, Masayuki, Hamaoka, Takafumi

“…Objective Human brown adipose tissue (BAT) activity has been typically evaluated by 18F‐fluorodeoxyglucose (FDG)‐positron emission tomography (PET) combined…”
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Melanin‐concentrating hormone‐producing neurons in the hypothalamus regulate brown adipose tissue and thus contribute to energy expenditure by Izawa, Shuntaro, Yoneshiro, Takeshi, Kondoh, Kunio, Nakagiri, Shohei, Okamatsu‐Ogura, Yuko, Terao, Akira, Minokoshi, Yasuhiko, Yamanaka, Akihiro, Kimura, Kazuhiro

“…Key points Melanin‐concentrating hormone (MCH) neuron‐ablated mice exhibit increased energy expenditure and reduced fat weight. Increased brown adipose tissue…”
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Association between thermogenic brown fat and genes under positive natural selection in circumpolar populations by Ishida, Yuka, Matsushita, Mami, Yoneshiro, Takeshi, Saito, Masayuki, Nakayama, Kazuhiro

“…Adaptation to cold was essential for human migration across Eurasia. Non-shivering thermogenesis through brown adipose tissue (BAT) participates in cold…”
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