Search Results - "Yoneshige, Azusa"

Cell adhesion molecule-1 shedding induces apoptosis of renal epithelial cells and exacerbates human nephropathies by Kato, Takashi, Hagiyama, Man, Takashima, Yasutoshi, Yoneshige, Azusa, Ito, Akihiko

“…Chronic kidney disease (CKD) is an important problem throughout the world, associated with the increase of blood urea nitrogen (BUN) and serum creatinine…”
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Performance of Oncomine Fusion Transcript kit for formalin‐fixed, paraffin‐embedded lung cancer specimens by Sakai, Kazuko, Ohira, Tatsuo, Matsubayashi, Jun, Yoneshige, Azusa, Ito, Akihiko, Mitsudomi, Tetsuya, Nagao, Toshitaka, Iwamatsu, Emi, Katayama, Jin, Ikeda, Norihiko, Nishio, Kazuto

“…Gene fusions play an important role in the carcinogenesis of lung adenocarcinoma. The recent association of four oncogenic driver genes, ALK, ROS1, RET, and…”
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Early Gene Expression Profile in Retinal Ganglion Cell Layer After Optic Nerve Crush in Mice by Ueno, Satoru, Yoneshige, Azusa, Koriyama, Yoshiki, Hagiyama, Man, Shimomura, Yoshikazu, Ito, Akihiko

“…Optic nerve crush (ONC) induces retinal ganglion cell (RGC) death, which causes vision loss in glaucoma. To investigate early events leading to apoptosis of…”
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Cell Adhesion Molecule 1 Contributes to Cell Survival in Crowded Epithelial Monolayers by Hagiyama, Man, Kimura, Ryuichiro, Yoneshige, Azusa, Inoue, Takao, Otani, Tomoyuki, Ito, Akihiko

“…When epithelial cells in vivo are stimulated to proliferate, they crowd and often grow in height. These processes are likely to implicate dynamic interactions…”
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Expression of cell adhesion molecule 1 in human and murine endometrial glandular cells and its increase during the proliferative phase by estrogen and cell density by Kimura, Ryuichiro, Otani, Tomoyuki, Shiraishi, Naoki, Hagiyama, Man, Yoneshige, Azusa, Wada, Akihiro, Kajiyama, Hiroshi, Takeuchi, Fuka, Mizuguchi, Nobuyuki, Morishita, Kazuhiro, Ito, Akihiko

“…Cell adhesion molecule 1 (CADM1) mediates interepithelial adhesion and is upregulated in crowded epithelial monolayers. This study aimed to examine CADM1…”
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Expression of cell adhesion molecule 1 in gastric neck and base glandular cells: Possible involvement in peritoneal dissemination of signet ring cells by Kimura, Ryuichiro, Yoneshige, Azusa, Hagiyama, Man, Otani, Tomoyuki, Inoue, Takao, Shiraishi, Naoki, Yanagihara, Kazuyoshi, Wakayama, Tomohiko, Ito, Akihiko

“…To determine cellular distribution of cell adhesion molecule 1 (CADM1), an immunoglobulin superfamily member, in the human oxyntic gastric mucosa, and to…”
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Increased ectodomain shedding of lung epithelial cell adhesion molecule 1 as a cause of increased alveolar cell apoptosis in emphysema by Mimae, Takahiro, Hagiyama, Man, Inoue, Takao, Yoneshige, Azusa, Kato, Takashi, Okada, Morihito, Murakami, Yoshinori, Ito, Akihiko

“…Alveolar epithelial cell apoptosis and protease/antiprotease imbalance based proteolysis play central roles in the pathogenesis of pulmonary emphysema but…”
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An antibody-drug conjugate for endometrioid carcinoma based on the expression of cell adhesion molecule 1 by Hagiyama, Man, Yoneshige, Azusa, Otani, Tomoyuki, Wada, Akihiro, Takeuchi, Fuka, Shoya, Yuji, Inoue, Takao, Ito, Akihiko

“…Cell adhesion molecule 1 (CADM1), an immunoglobulin superfamily member, is expressed in endometrial glandular cells highly during the proliferative phase but…”
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Indigo plant leaf extract inhibits the binding of SARS‑CoV‑2 spike protein to angiotensin‑converting enzyme 2 by Hagiyama, Man, Takeuchi, Fuka, Sugano, Aki, Yoneshige, Azusa, Inoue, Takao, Wada, Akihiro, Kajiyama, Hiroshi, Takaoka, Yutaka, Sasaki, Kenroh, Ito, Akihiko

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses its S1 spike protein to bind to angiotensin-converting enzyme 2 (ACE2) on human cells in the…”
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Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing by Sakai, Kazuko, Tsurutani, Junji, Yamanaka, Takeharu, Yoneshige, Azusa, Ito, Akihiko, Togashi, Yosuke, De Velasco, Marco A, Terashima, Masato, Fujita, Yoshihiko, Tomida, Shuta, Tamura, Takao, Nakagawa, Kazuhiko, Nishio, Kazuto

“…Somatic mutations in KRAS, NRAS, and BRAF genes are related to resistance to anti-EGFR antibodies in colorectal cancer. We have established an extended RAS and…”
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Chemoenzymatic Synthesis of Hydrophobic Glycoprotein: Synthesis of Saposin C Carrying Complex-Type Carbohydrate by Hojo, Hironobu, Tanaka, Hiromasa, Hagiwara, Masashi, Asahina, Yuya, Ueki, Akiharu, Katayama, Hidekazu, Nakahara, Yuko, Yoneshige, Azusa, Matsuda, Junko, Ito, Yukishige, Nakahara, Yoshiaki

“…The complex-type N-linked octasaccharide oxazoline having LacNAc as the nonreducing end sugar was efficiently synthesized using the benzyl-protected LacNAc,…”
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Modest Static Pressure Can Cause Enteric Nerve Degeneration Through Ectodomain Shedding of Cell Adhesion Molecule 1 by Yoneshige, Azusa, Hagiyama, Man, Inoue, Takao, Tanaka, Tomonori, Ri, Aritoshi, Ito, Akihiko

“…Internal pressure is often involved in neurodegeneration; intraocular and intraventricular pressure elevations over 20–30 cmH 2 O cause glaucoma and…”
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High-performance thin-layer chromatography/mass spectrometry for the analysis of neutral glycosphingolipids by Suzuki, Akemi, Miyazaki, Masao, Matsuda, Junko, Yoneshige, Azusa

“…This mini-review summarizes the protocol we have developed for the analysis of neutral glycosphingolipids (GSLs) by high-performance thin layer chromatography…”
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A mutation in the saposin C domain of the sphingolipid activator protein (Prosaposin) gene causes neurodegenerative disease in mice by Yoneshige, Azusa, Suzuki, Kinuko, Suzuki, Kunihiko, Matsuda, Junko

“…Saposins A, B, C, and D are small amphiphatic glycoproteins that are encoded in tandem within a precursor protein (prosaposin, PSAP), and are required for in…”
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Elevated Hydrostatic Pressure Causes Retinal Degeneration Through Upregulating Lipocalin-2 by Yoneshige, Azusa, Hagiyama, Man, Takashima, Yasutoshi, Ueno, Satoru, Inoue, Takao, Kimura, Ryuichiro, Koriyama, Yoshiki, Ito, Akihiko

“…Elevation of intraocular pressure is a major risk factor for glaucoma development, which causes the loss of retinal ganglion cells (RGCs). Lipocalin 2 (Lcn2)…”
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Increased ectodomain shedding of cell adhesion molecule 1 from pancreatic islets in type 2 diabetic pancreata: correlation with hemoglobin A1c levels by Inoue, Takao, Hagiyama, Man, Yoneshige, Azusa, Kato, Takashi, Enoki, Eisuke, Maenishi, Osamu, Chikugo, Takaaki, Kimura, Masatomo, Satou, Takao, Ito, Akihiko

“…Pulmonary emphysema and type 2 diabetes mellitus (T2DM), both caused by lifestyle factors, frequently concur. Respectively, the diseases affect lung alveolar…”
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The intracellular domain of cell adhesion molecule 1 is present in emphysematous lungs and induces lung epithelial cell apoptosis by Hagiyama, Man, Yoneshige, Azusa, Inoue, Takao, Sato, Yasufumi, Mimae, Takahiro, Okada, Morihito, Ito, Akihiko

“…Pulmonary emphysema is characterized histologically by destruction of alveolar walls and enlargement of air spaces due to lung epithelial cell apoptosis. Cell…”
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Possible Therapeutic Utility of anti-Cell Adhesion Molecule 1 Antibodies for Malignant Pleural Mesothelioma by Hagiyama, Man, Mimae, Takahiro, Wada, Akihiro, Takeuchi, Fuka, Yoneshige, Azusa, Inoue, Takao, Kotoku, Naoyuki, Hamada, Hironobu, Sekido, Yoshitaka, Okada, Morihito, Ito, Akihiko

“…Malignant pleural mesothelioma (MPM) is a highly aggressive malignant tumor, and the effective therapeutic drugs are limited. Thus, the establishment of novel…”
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function of sphingolipids in the nervous system: lessons learnt from mouse models of specific sphingolipid activator protein deficiencies by Yoneshige, Azusa, Suzuki, Kunihiko

“…We have generated specific saposin A and D deficient mouse mutants by the gene targeting technology. Saposin A deficient mice showed the clinical, biochemical…”
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Manifestation of osteoblastic phenotypes in the sarcomatous component of epithelial carcinoma and sarcomatoid carcinoma by Takashima, Yasutoshi, Murakami, Teppei, Inoue, Takao, Hagiyama, Man, Yoneshige, Azusa, Nishimura, Syunji, Akagi, Masao, Ito, Akihiko

“…Epithelial carcinomas occasionally have sarcomatous components that consist primarily of spindle and cuboidal cells, which often resemble osteoblasts…”
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