Search Results - "Yonenaga, Norihito"

RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment by Yonenaga, Norihito, Kenjo, Eriya, Asai, Tomohiro, Tsuruta, Atsushi, Shimizu, Kosuke, Dewa, Takehisa, Nango, Mamoru, Oku, Naoto

“…For the purpose of systemic delivery of siRNA, we previously developed polycation liposomes (PCLs) containing dicetylphosphate-tetraethylenepentamine…”
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Systemic Delivery of Small Interfering RNA by Use of Targeted Polycation Liposomes for Cancer Therapy by Kenjo, Eriya, Asai, Tomohiro, Yonenaga, Norihito, Ando, Hidenori, Ishii, Takayuki, Hatanaka, Kentaro, Shimizu, Kosuke, Urita, Yugo, Dewa, Takehisa, Nango, Mamoru, Tsukada, Hideo, Oku, Naoto

“…Novel polycation liposomes decorated with cyclic(Cys-Arg-Gly-Asp-D-Phe) peptide (cyclicRGD)-polyethylene glycol (PEG) (RGD-PEG-polycation liposomes (PCL)) were…”
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Susceptibility of PTEN-positive metastatic tumors to small interfering RNA targeting the mammalian target of rapamycin by Koide, Hiroyuki, PhD, Asai, Tomohiro, PhD, Kato, Hiroki, BS, Yonenaga, Norihito, MS, Yokota, Masafumi, Ando, Hidenori, PhD, Dewa, Takehisa, PhD, Nango, Mamoru, PhD, Maeda, Noriyuki, PhD, Oku, Naoto, PhD

“…Abstract PTEN-positive tumors are not susceptible to the treatment with rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR). Here, we…”
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RNA創薬研究におけるポジトロン標識small interfering RNA (siRNA) の positron emission tomography (PET) 体内動態イメージング by 安藤, 英紀, 米永, 憲史, 浅井, 知浩, 畑中, 剣太朗, 小出, 裕之, 都竹, 拓磨, 原田, 典弘, 塚田, 秀夫, 奥, 直人

“…「1. はじめに」small interfering RNA(siRNA)は, 21-23塩基対の2本鎖核酸分子であり, 配列特異的な遺伝子サイレンシングを引き起こすことから, 1,2)遺伝子疾患や難治性疾患を始めとする, 今まで治療が困難であった様々な疾患に対する新規治療薬として, 近年大きな注目を集めている3)…”
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Dicetyl Phosphate-Tetraethylenepentamine-Based Liposomes for Systemic siRNA Delivery by Asai, Tomohiro, Matsushita, Saori, Kenjo, Eriya, Tsuzuku, Takuma, Yonenaga, Norihito, Koide, Hiroyuki, Hatanaka, Kentaro, Dewa, Takehisa, Nango, Mamoru, Maeda, Noriyuki, Kikuchi, Hiroshi, Oku, Naoto

“…Dicetyl phosphate-tetraethylenepentamine (DCP-TEPA) conjugate was newly synthesized and formed into liposomes for efficient siRNA delivery. Formulation of…”
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RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment: Past, current and future applications of liposomes - Grand Challenges and Opportunities in Nanomedicine by YONENAGA, Norihito, KENJO, Eriya, ASAI, Tomohiro, TSURUTA, Atsushi, SHIMIZU, Kosuke, DEWA, Takehisa, NANGO, Mamoru, OKU, Naoto

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In Vivo Imaging of Liposomal Small Interfering RNA (siRNA) Trafficking by Positron Emission Tomography by Ando, Hidenori, Yonenaga, Norihito, Asai, Tomohiro, Hatanaka, Kentaro, Koide, Hiroyuki, Tsuzuku, Takuma, Harada, Norihiro, Tsukada, Hideo, Oku, Naoto

“…In the development of nucleic acid medicines such as small interfering RNA (siRNA) drugs, one problem is how to study the pharmacokinetics and…”
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