Search Results - "Yokoyama, Masataka"

Impact of Preoperative Environmental Enrichment on Prevention of Development of Cognitive Impairment following Abdominal Surgery in a Rat Model by Kawano, Takashi, Eguchi, Satoru, Iwata, Hideki, Tamura, Takahiko, Kumagai, Naoko, Yokoyama, Masataka

“…Sustained neuroinflammation may contribute to the pathogenesis of postoperative cognitive dysfunction (POCD). Here, the authors evaluated the preventive effect…”
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A crucial role for adipose tissue p53 in the regulation of insulin resistance by Komuro, Issei, Minamino, Tohru, Orimo, Masayuki, Shimizu, Ippei, Kunieda, Takeshige, Yokoyama, Masataka, Ito, Takashi, Nojima, Aika, Nabetani, Akira, Oike, Yuichi, Matsubara, Hisahiro, Ishikawa, Fuyuki

“…Various stimuli, such as telomere dysfunction and oxidative stress, can induce irreversible cell growth arrest, which is termed 'cellular senescence'. This…”
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TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia by Ochiiwa, Hiroaki, Ailiken, Guzhanuer, Yokoyama, Masataka, Yamagata, Kazuyuki, Nagano, Hidekazu, Yoshimura, Chihoko, Muraoka, Hiromi, Ishida, Keiji, Haruma, Tomonori, Nakayama, Akitoshi, Hashimoto, Naoko, Murata, Kazutaka, Nishimura, Motoi, Kawashima, Yusuke, Ohara, Osamu, Ohkubo, Shuichi, Tanaka, Tomoaki

“…TAS4464, a potent, selective small molecule NEDD8-activating enzyme (NAE) inhibitor, leads to inactivation of cullin-RING E3 ubiquitin ligases (CRLs) and…”
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Molecular determinants of nephron vascular specialization in the kidney by Barry, David M., McMillan, Elizabeth A., Kunar, Balvir, Lis, Raphael, Zhang, Tuo, Lu, Tyler, Daniel, Edward, Yokoyama, Masataka, Gomez-Salinero, Jesus M., Sureshbabu, Angara, Cleaver, Ondine, Di Lorenzo, Annarita, Choi, Mary E., Xiang, Jenny, Redmond, David, Rabbany, Sina Y., Muthukumar, Thangamani, Rafii, Shahin

“…Although kidney parenchymal tissue can be generated in vitro, reconstructing the complex vasculature of the kidney remains a daunting task. The molecular…”
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Intensive Versus Intermediate Glucose Control in Surgical Intensive Care Unit Patients by OKABAYASHI, Takehiro, SHIMA, Yasuo, SUMIYOSHI, Tatsuaki, KOZUKI, Akihito, TOKUMARU, Teppei, IIYAMA, Tasuo, SUGIMOTO, Takeki, KOBAYASHI, Michiya, YOKOYAMA, Masataka, HANAZAKI, Kazuhiro

“…The optimal perioperative blood glucose range to improve surgical site infection (SSI) in surgical intensive care unit (ICU) patients remains unclear. We…”
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Prevention of atrial fibrillation after cardiac surgery using low-dose landiolol: A systematic review and meta-analysis by Tamura, Takahiko, Yatabe, Tomoaki, Yokoyama, Masataka

“…Atrial fibrillation (AF) is associated with mortality after cardiac surgery. Several studies have reported that landiolol might help to prevent postoperative…”
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Effects of dexamethasone on local infiltration analgesia in total knee arthroplasty: a randomized controlled trial by Ikeuchi, Masahiko, Kamimoto, Yuko, Izumi, Masashi, Fukunaga, Kayo, Aso, Koji, Sugimura, Natsuki, Yokoyama, Masataka, Tani, Toshikazu

“…Purpose Intraoperative local infiltration analgesia has gained increasing popularity in joint replacement surgery. Because there is considerable variation…”
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Lower Body Mass Index is Associated with Hospital Mortality in Critically ill Japanese Patients by Yatabe, Tomoaki, Yamashita, Koichi, Yokoyama, Masataka

“…Background and Objectives: A recent observational study conducted in European intensive care units (ICU) showed that body mass index (BMI) is associated with…”
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Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats by Locatelli, Fabricio M., Kawano, Takashi, Iwata, Hideki, Aoyama, Bun, Eguchi, Satoru, Nishigaki, Atsushi, Yamanaka, Daiki, Tateiwa, Hiroki, Shigematsu-Locatelli, Marie, Yokoyama, Masataka

“…The maladaptive response of aged microglia to surgery and consequent neuroinflammation plays a key pathogenic role in postoperative cognitive dysfunction…”
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Comparative analysis of aldosterone and renin assays for primary aldosteronism screening by Taki, Yuki, Kono, Takashi, Teruyama, Kyoko, Ichijo, Takamasa, Sakuma, Ikki, Nagano, Hidekazu, Miyagawa, Hiroka, Kono, Satomi, Fujimoto, Masanori, Hashimoto, Naoko, Yokoyama, Masataka, Kawakami, Eiryo, Miki, Takashi, Tanaka, Tomoaki

“…The transition from radioimmunoassay (RIA) to chemiluminescent enzyme immunoassay (CLEIA) for plasma aldosterone concentration (PAC) assays has raised concerns…”
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Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis by Fujimoto, Masanori, Yokoyama, Masataka, Kiuchi, Masahiro, Hosokawa, Hiroyuki, Nakayama, Akitoshi, Hashimoto, Naoko, Sakuma, Ikki, Nagano, Hidekazu, Yamagata, Kazuyuki, Kudo, Fujimi, Manabe, Ichiro, Lee, Eunyoung, Hatano, Ryo, Onodera, Atsushi, Hirahara, Kiyoshi, Yokote, Koutaro, Miki, Takashi, Nakayama, Toshinori, Tanaka, Tomoaki

“…The liver stores glycogen and releases glucose into the blood upon increased energy demand. Group 2 innate lymphoid cells (ILC2) in adipose and pancreatic…”
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p53-Induced Adipose Tissue Inflammation Is Critically Involved in the Development of Insulin Resistance in Heart Failure by Shimizu, Ippei, Yoshida, Yohko, Katsuno, Taro, Tateno, Kaoru, Okada, Sho, Moriya, Junji, Yokoyama, Masataka, Nojima, Aika, Ito, Takashi, Zechner, Rudolf, Komuro, Issei, Kobayashi, Yoshio, Minamino, Tohru

“…Several clinical studies have shown that insulin resistance is prevalent among patients with heart failure, but the underlying mechanisms have not been fully…”
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Brain-Derived Neurotrophic Factor Protects Against Cardiac Dysfunction After Myocardial Infarction via a Central Nervous System–Mediated Pathway by Okada, Sho, Yokoyama, Masataka, Toko, Haruhiro, Tateno, Kaoru, Moriya, Junji, Shimizu, Ippei, Nojima, Aika, Ito, Takashi, Yoshida, Yohko, Kobayashi, Yoshio, Katagiri, Hideki, Minamino, Tohru, Komuro, Issei

“…OBJECTIVE—The central nervous system is thought to influence the regulation of the cardiovascular system in response to humoral and neural signals from…”
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The History and the Future of Peripheral Nerve Block by Yokoyama, Masataka

“…Peripheral nerve block became popular with the advance of the ultrasonic diagnostic equipment, and became one of the essential procedures in anesthesia. For…”
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Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents by Shimizu, Ippei, Minamino, Tohru, Toko, Haruhiro, Okada, Sho, Ikeda, Hiroyuki, Yasuda, Noritaka, Tateno, Kaoru, Moriya, Junji, Yokoyama, Masataka, Nojima, Aika, Koh, Gou Young, Akazawa, Hiroshi, Shiojima, Ichiro, Kahn, C Ronald, Abel, E Dale, Komuro, Issei

“…Although many animal studies indicate insulin has cardioprotective effects, clinical studies suggest a link between insulin resistance (hyperinsulinemia) and…”
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Extension of bacterial rDNA sequencing for simultaneous methylation detection and its application in microflora analysis by Nishimura, Motoi, Tanaka, Tomoaki, Murata, Syota, Miyabe, Akiko, Ishige, Takayuki, Kawasaki, Kenji, Yokoyama, Masataka, Hashimoto, Naoko, Yamagata, Kazuyuki, Nagano, Hidekazu, Tojo-Nishimura, Satomi, Matsushita, Kazuyuki

“…Although polymerase chain reaction (PCR) amplification and sequencing of the bacterial 16S rDNA region has numerous scientific applications, it does not…”
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Identification of risk factors for post-induction hypotension in patients receiving 5-aminolevulinic acid: a single-center retrospective study by Yatabe, Tomoaki, Karashima, Takashi, Kume, Motohiko, Kawanishi, Yu, Fukuhara, Hideo, Ueba, Tetsuya, Inoue, Keiji, Okuhara, Yoshiyasu, Yokoyama, Masataka

“…Background 5-Aminolevulinic acid (5-ALA) is useful as a photodynamic agent, but its use commonly leads to hypotension. Although avoiding a mean arterial…”
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Inhibition of Endothelial p53 Improves Metabolic Abnormalities Related to Dietary Obesity by Yokoyama, Masataka, Okada, Sho, Nakagomi, Atsushi, Moriya, Junji, Shimizu, Ippei, Nojima, Aika, Yoshida, Yohko, Ichimiya, Harumi, Kamimura, Naomi, Kobayashi, Yoshio, Ohta, Shigeo, Fruttiger, Marcus, Lozano, Guillermina, Minamino, Tohru

“…Accumulating evidence has suggested a role for p53 activation in various age-associated conditions. Here, we identified a crucial role of endothelial p53…”
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MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway by Aersilan, Alimasi, Hashimoto, Naoko, Yamagata, Kazuyuki, Yokoyama, Masataka, Nakayama, Akitoshi, Shi, Xiaoyan, Nagano, Hidekazu, Sakuma, Ikki, Nohata, Nijiro, Kinoshita, Takashi, Seki, Naohiko, Rahmutulla, Bahityar, Kaneda, Atsushi, Zhahara, Siti Nurul, Gong, Yingbo, Nishimura, Motoi, Kawauchi, Shoichiro, Kawakami, Eiryo, Tanaka, Tomoaki

“…The microRNA (miR) miR-874 , a potential tumour suppressor, causes cell death via target gene suppression in various cancer types. Mevalonate pathway…”
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5-Aminolevulinic acid-induced severe hypotension during transurethral resection of a bladder tumor: a case report by Yatabe, Tomoaki, Marie, Shigematsu-Locatelli, Fukuhara, Hideo, Karashima, Takeshi, Inoue, Keiji, Yokoyama, Masataka

“…Background Although 5-aminolevulinic acid (5-ALA) is used for the photodynamic diagnosis of bladder tumors, hypotension is the most commonly observed adverse…”
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