Search Results - "Yokota, S. J."

THE NEXT GENERATION OF LIPOSOME DELIVERY SYSTEMS: RECENT EXPERIENCE WITH TUMOR-TARGETED, STERICALLY-STABILIZED IMMUNOLIPOSOMES AND ACTIVE-LOADING GRADIENTS by Abra, R. M., Bankert, R. B., Chen, F., Egilmez, N. K., Huang, K., Saville, R., Slater, J. L., Sugano, M., Yokota, S. J.

“…ABSTRACT Three topics are discussed. Enhanced anti-tumor efficacy of targeted doxorubicin-containing sterically-stabilized liposomes using an anti-β1 integrin…”
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In vivo cytokine gene therapy of human tumor xenografts in SCID mice by liposome-mediated DNA delivery by Egilmez, N K, Cuenca, R, Yokota, S J, Sorgi, F, Bankert, R B

“…The human interleukin-2 (IL-2) gene was successfully delivered into established human tumor xenografts in SCID (severe combined immunodeficient) mice by…”
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Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice by SUGANO, Masahiko, EGILMEZ, Nejat K, YOKOTA, Sandra J, CHEN, Fang-An, HARDING, Jennifer, SHI KUN HUANG, BANKERT, Richard B

“…Beta1 integrins, expressed on the cell surface of human non-small cell lung carcinomas, are used here as a target for the selective delivery of anti-cancer…”
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COOH terminus of membrane IgM is essential for an antigen-specific induction of some but not all early activation events in mature B cells by PARIKH, V. S, NAKAI, C, YOKOTA, S. J, BANKERT, R. B, TUCKER, P. W

“…Transfectants of mature B cell lines that bind phosphorylcholine were made in order to understand the role of the COOH terminus of the mu chain of membrane IgM…”
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The effect of free fatty acids on spectrin organization in lymphocytes by Stephen, F D, Yokota, S J, Repasky, E A

“…Previous studies have shown that cis unsaturated free fatty acids (uFFAs) are able to cause alterations in the normal distribution pattern of certain…”
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IL-12 delivered intratumorally by multilamellar liposomes reactivates memory T cells in human tumor microenvironments by Simpson-Abelson, Michelle R, Purohit, Vivek S, Pang, Wing Man, Iyer, Vandana, Odunsi, Kunle, Demmy, Todd L, Yokota, Sandra J, Loyall, Jenni L, Kelleher, Raymond J, Balu-Iyer, Sathy, Bankert, Richard B

“…Abstract Using a novel loading technique, IL-12 is reported here to be efficiently encapsulated within large multilamellar liposomes. The preclinical efficacy…”
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Human CD4+ effector memory T cells persisting in the microenvironment of lung cancer xenografts are activated by local delivery of IL-12 to proliferate, produce IFN-gamma, and eradicate tumor cells by Broderick, Lori, Yokota, Sandra J, Reineke, Joshua, Mathiowitz, Edith, Stewart, Carleton C, Barcos, Maurice, Kelleher, Jr, Raymond J, Bankert, Richard B

“…The implantation of small pieces of human primary lung tumor biopsy tissue into SCID mice results in a viable s.c. xenograft in which the tissue architecture,…”
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