Search Results - "Yokoshiki, H"

Inhibition of L-type Calcium Current in Rat Ventricular Cells by the Tyrosine Kinase Inhibitor, Genistein and its Inactive Analog, Daidzein by Yokoshiki, Hisashi, Sumii, Kotaro, Sperelakis, Nicholas

“…Effects of genistein, a specific inhibitor of tyrosine kinase, on the l-type Ca 2+channels were examined in freshly isolated young (days 10–18) rat ventricular…”
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Antisense oligodeoxynucleotides of sulfonylurea receptors inhibit ATP-sensitive K+ channels in cultured neonatal rat ventricular cells by Yokoshiki, H, Sunagawa, M, Seki, T, Sperelakis, N

“…To identify the functional sulfonylurea receptor (SUR), a subunit of the adenosine 5'-triphosphate (ATP)-sensitive K+ (KATP) channels, in neonatal rat…”
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Regulation of Ca2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery by Yokoshiki, H, Katsube, Y, Sperelakis, N

“…Regulation of L-type Ca2+ channels of vascular smooth muscle (VSM) cells by adenosine 3',5'-cyclic monophosphate (cAMP)-dependent and guanosine 3',5'-cyclic…”
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Disruption of actin cytoskeleton attenuates sulfonylurea inhibition of cardiac ATP-sensitive K+ channels by Yokoshiki, H, Katsube, Y, Sunugawa, M, Seki, T, Sperelakis, N

“…Two actin filament-depolymerizing agents, DNase I and cytochalasin D, were used to examine the involvement of the cytoskeleton in the functional interaction…”
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Regulation of the slow Ca++ channels of myocardial cells by Sperelakis, N, Katsube, Y, Yokoshiki, H, Sada, H, Sumii, K

“…Contraction of the heart is regulated by a number of mechanisms, such as neurotransmitters, hormones, autacoids, pH, intracellular ATP, and Ca++ ions. These…”
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Regulation of ion channels in myocardial cells and protection of ischemic myocardium by SPERELAKIS, N, SUNAGAWA, M, YOKOSHIKI, H, SEKI, T, NAKAMURA, M

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Effect of chronic antihypertensive treatment on ischemia-induced lethal ventricular tachyarrhythmias and electrophysiological property in hypertrophied rat hearts by Yokoshiki, H

“…The purpose of the study is to test the hypothesis that regression of left ventricular hypertrophy (LVH) prevents sudden cardiac death caused by lethal…”
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P1590Ischemia-induced small-conductance calcium-activated potassium channel activation deteriorates ventricular arrhythmias in cardiac hypertrophy through the CaMKII-dependent pathway by Tenma, T., Mitsuyama, H., Watanabe, M., Mizukami, K., Kamada, R., Takahashi, M., Takada, S., Tsutsui, H., Yokoshiki, H.

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Abrupt augmentation of ST segment elevation associated with successful reperfusion: A sign of diminished myocardial salvage by Yokoshiki, Hisashi, Kohya, Tetsuro, Tateda, Kunihiko, Shishido, Toshiaki, Hirasawa, Kunihiko, Kitabatake, Akira

“…To investigate the significance of abrupt augmentation of ST segment elevation immediately after reperfusion, 36 patients with an initial acute anterior…”
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Point catheter ablation of macro-re-entrant ventricular tachycardia in a patient after surgical repair for double-outlet right ventricle by Izumi, Gaku, Yokoshiki, Hisashi, Takeda, Atsuhito

“…Catheter ablation of ventricular tachycardia is often difficult in patients after surgery for CHD. In patients with a ventricular septal defect patch, it is…”
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Cardiac profile of EGIS-9377, a novel cardiotonic agent as a Ca2+ sensitizer with bradycardiac activity by Hattori, Y, Ishitani, T, Tomita, F, Gando, S, Yokoshiki, H, Azuma, M, Kemmotsu, O, Kanno, M

“…The cardiac profile of EGIS-9377 ¿2-(1-methylthio)-5-(2-morpholinoethylamino)-8,9-dihydro-7H-thi opyrano[3,2-d][1,2,4]triazolo[1,5-a]pyrimidine…”
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Randomized trial of angiotensin II-receptor blocker vs. dihydropiridine calcium channel blocker in the treatment of paroxysmal atrial fibrillation with hypertension (J-RHYTHM II study) by Yamashita, Takeshi, Inoue, Hiroshi, Okumura, Ken, Kodama, Itsuo, Aizawa, Yoshifusa, Atarashi, Hirotsugu, Ohe, Tohru, Ohtsu, Hiroshi, Kato, Takao, Kamakura, Shiro, Kumagai, Koichiro, Kurachi, Yoshihisa, Koretsune, Yukihiro, Saikawa, Tetsunori, Sakurai, Masayuki, Sato, Toshiaki, Sugi, Kaoru, Nakaya, Haruaki, Hirai, Makoto, Hirayama, Atsushi, Fukatani, Masahiko, Mitamura, Hideo, Yamazaki, Tsutomu, Watanabe, Eiichi, Ogawa, Satoshi

“…Atrial fibrillation (AF) is a common arrhythmia frequently associated with hypertension. This study was designed to test the hypothesis that lowering blood…”
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Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes by YOKOSHIKI, H, KATSUBE, Y, SUNAGAWA, M, SPERELAKIS, N

“…The electrophysiological effect of levosimendan, a novel Ca(2+)-sensitizing positive inotropic agent and vasodilator, was examined on rat mesenteric arterial…”
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ATP-sensitive K+ channels in pancreatic, cardiac, and vascular smooth muscle cells by Yokoshiki, H, Sunagawa, M, Seki, T, Sperelakis, N

“…ATP-sensitive K+ (KATP) channels are therapeutic targets for several diseases, including angina, hypertension, and diabetes. This is because stimulation of…”
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Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms by Makita, Naomasa, Sasaki, Koji, Groenewegen, W Antoinette, Yokota, Takashi, Yokoshiki, Hisashi, Murakami, Tomoaki, Tsutsui, Hiroyuki

“…Congenital atrial standstill has been linked to SCN5A. Incomplete penetrance observed in atrial standstill has been attributed in part to the digenic…”
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The novel calcium sensitizer levosimendan activates the ATP-sensitive K+ channel in rat ventricular cells by Yokoshiki, H, Katsube, Y, Sunagawa, M, Sperelakis, N

“…Levosimendan, a new Ca++-sensitizing and positive inotropic agent, was reported to act as a coronary vasodilator and protect ischemic myocardium. To elucidate…”
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Vasodilating mechanisms of levosimendan by Yokoshiki, Hisashi, Sperelakis, Nicholas

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Prevalence and Clinical Characteristics of Patients With Atrial Fibrillation: Analysis of 20, 000 Cases in Japan by Tomita, Fumishi, Kohya, Tetsuro, Sakurai, Masayuki, Kaji, Tohru, Yokoshiki, Hisashi, Sato, Minoru, Sasaki, Kohji, Itoh, Yoshinori, Konno, Masanori, Kitabatake, Akira

“…In Japan, data on the epidemiological and clinical features of atrial fibrillation (AF) are rather sparse; even less data are available on the risk of…”
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Angiotensin II stimulation of Ca2+-channel current in vascular smooth muscle cells is inhibited by lavendustin-A and LY-294002 by Seki, T, Yokoshiki, H, Sunagawa, M, Nakamura, M, Sperelakis, N

“…Angiotensin II (AngII) is coupled to several important intracellular signaling pathways, and increases intracellular Ca2+. In vascular smooth muscle (VSM)…”
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Detection of Amiodarone-Induced Pulmonary Toxicity in Supine and Prone Positions: High-Resolution Computed Tomography Study by Oyama, Noriko, Oyama, Naotsugu, Yokoshiki, Hisashi, Kamishima, Tamotsu, Nambu, Toshikazu, Tsutsui, Hiroyuki, Miyasaka, Kazuo

“…Background The aim of the present study was to describe the effectiveness and feasibility of high-resolution computed tomography (HRCT) in patients in supine…”
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