Search Results - "Yokoi, F."

Cell-specific Dyt1 ∆GAG knock-in to basal ganglia and cerebellum reveal differential effects on motor behavior and sensorimotor network function by Wilkes, B.J., Adury, R.Z., Berryman, D., Concepcion, L.R., Liu, Y., Yokoi, F., Maugee, C., Li, Y., Vaillancourt, D.E.

“…Dystonia is a neurological movement disorder characterized by repetitive, unintentional movements and disabling postures that result from sustained or…”
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Analysis of BTBD9 conditional knockout mice as models of restless legs syndrome by Li, Y, Deandrade, M, Yokoi, F

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Motor Deficits and Hyperactivity in Cerebral Cortex-specific Dyt1 Conditional Knockout Mice by Yokoi, Fumiaki, Dang, Mai Tu, Mitsui, Shinichi, Li, Jianyong, Li, Yuqing

“…DYT1 dystonia is a primary generalized early-onset torsion dystonia caused by mutations in DYT1 that codes for torsinA and has an autosomal dominant…”
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Hyperactivity and alterations in iron homeostasis in mu opioid receptor knockout mice: possible implications for restless legs syndrome/Willis-Ekbom disease by Deandrade, M, Unger, E, Zhang, L, Yokoi, F, Walters, A, Li, Y

“…Introduction Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder that is manifested generally at rest by an urge to…”
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Molecular Cloning of a cDNA for the Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase by Yokoi, Fumiaki, Hiraishi, Hiroyuki, Izuhara, Kenji

“…We previously reported the isolation from bovine liver of a novel 56-kDa inorganic pyrophosphatase named phospholysine phosphohistidine inorganic pyrophosphate…”
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Dopamine Transporters are Markedly Reduced in Lesch-Nyhan Disease in vivo by Wong, Dean F., Harris, James C., Naidu, Sakkubai, Yokoi, Fuji, Marenco, Stefano, Dannals, Robert F., Ravert, Hayden T., Yaster, Myron, Evans, Alan, Rousset, Olivier, Bryan, R. Nick, Gjedde, Albert, Kuhar, Michael J., Breese, George R.

“…Dopamine (DA) deficiency has been implicated in Lesch-Nyhan disease (LND), a genetic disorder that is characterized by hyperuricemia, choreoathetosis,…”
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Cell-specific Dyt1 ΔGAG knock-in to basal ganglia and cerebellum reveal differential effects on motor behavior and sensorimotor network function by Wilkes, B.J., Adury, R.Z., Berryman, D., Concepcion, L.R., Liu, Y., Yokoi, F., Maugee, C., Li, Y., Vaillancourt, D.E.

“…Dystonia is a neurological movement disorder characterized by repetitive, unintentional movements and disabling postures that result from sustained or…”
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Bovine liver phosphoamidase as a protein histidine/lysine phosphatase by Hiraishi, H, Yokoi, F, Kumon, A

“…A 13-kDa phosphoamidase was isolated as a single band on SDS-PAGE from bovine liver. Its Stokes' radius, sedimentation coefficient, molecular mass, and optimal…”
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P2839Significance of cell-specific precise computer simulation using new mathematical models of human induced pluripotent stem cell derived cardiomyocyte in drug testing by Kohjitani, H, Kouda, S, Himeno, Y, Makiyama, T, Yokoi, F, Hirose, S, Wuriyanghai, Y, Yamamoto, Y, Horie, M, Kimura, T, Noma, A, Amano, A

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Radiolabeled Neuronal Nitric Oxide Synthase Inhibitors: Synthesis, In Vivo Evaluation, and Primate PET Studies by Pomper, Martin G, Musachio, John L, Scheffel, Ursula, Macdonald, James E, McCarthy, Dennis J, Reif, David W, Villemagne, Victor L, Yokoi, Fuji, Dannals, Robert F, Wong, Dean F

“…The objectives of this study were to synthesize neuronal nitric oxide synthase (NOS-I)-selective imaging agents based on the 2 potent, selective inhibitors…”
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Abnormal nuclear envelopes in the striatum and motor deficits in DYT11 myoclonus-dystonia mouse models by Yokoi, Fumiaki, Dang, Mai T., Zhou, Tong, Li, Yuqing

“…DYT11 myoclonus-dystonia (M-D) is a movement disorder characterized by myoclonic jerks with dystonic symptoms and caused by mutations in paternally expressed…”
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[11C]WIN-35,428 PET Imaging Reveals Decreased Dopamine Transporter Density in Abstinent Methamphetamine Users by Wong, D.F., McCann, U.D., Yokoi, F., Villemagne, V., Dannals, R.F., Ricaurte, G.A.

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Partial Volume Effects on Dopamine Transporters in Normal Human and Rett Syndrome Brain: Graphical Kinetic Modeling for [11C]WIN 35,428 with No Blood Input by Yokoi, F., Rousset, O.G., Dogan, A.S., Stephane, M., Naidu, S., Wong, D.F.

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Dopamine D2 and D3 Receptor Occupancy in Normal Humans Treated with the Antipsychotic Drug Aripiprazole (OPC 14597): A Study Using Positron Emission Tomography and [11C]Raclopride by Yokoi, Fuji, Ph.D, M.D, Gründer, Gerhard, Biziere, Kathleen, Stephane, Massoud, Dogan, Ahmet S, Dannals, Robert F, Ravert, Hayden, Suri, Ajit, Bramer, Steven, Wong, Dean F

“…Aripiprazole (OPC 14597) is an antipsychotic drug that has high affinity for dopamine D2 and D3 receptors and the dopamine autoreceptor. It is being developed…”
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Correction: Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice

“…The funders had no role in either the study design, data collection and analysis, decision to publish, or preparation of the manuscript. (2015) Behavioral and…”
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Generation and characterization of Dyt1 ΔGAG knock-in mouse as a model for early-onset dystonia by Dang, Mai T., Yokoi, Fumiaki, McNaught, Kevin St. P., Jengelley, Toni-Ann, Jackson, Tehone, Li, Jianyong, Li, Yuqing

“…A trinucleotide deletion of GAG in the DYT1 gene that encodes torsinA protein is implicated in the neurological movement disorder of Oppenheim's early-onset…”
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Elevated Intrasynaptic Dopamine Release in Tourette's Syndrome Measured by PET by Singer, Harvey S., Szymanski, Sally, Giuliano, Joseph, Yokoi, Fuji, Dogan, A. Semih, Brasic, James R., Zhou, Yun, Grace, Anthony A., Wong, Dean F.

“…OBJECTIVE: Dopaminergic abnormalities in frontal-subcortical circuits have been hypothesized as the underlying pathophysiologic mechanism in Tourette's…”
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Dopamine transporter imaging with novel, selective cocaine analogs by Scheffel, U, Dannals, R F, Wong, D F, Yokoi, F, Carroll, F I, Kuhar, M J

“…RTI-121 and RTI-122 are 3 beta-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [123I]RTI-121…”
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N(omega)-phosphoarginine phosphatase (17 kDa) and alkaline phosphatase as protein arginine phosphatases by Kumon, A, Kodama, H, Kondo, M, Yokoi, F, Hiraishi, H

“…Seven synthetic polymers, (Glu4, Tyr)n, (Arg)n, (Arg, Pro, Thr)n, (Arg-Gly-Glu)6, (Arg-Gly-Phe)6, (Glu-Arg-Gly-Phe)5, and…”
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Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428 by McCann, Una D, Wong, Dean F, Yokoi, Fuji, Villemagne, Victor, Dannals, Robert F, Ricaurte, George A

“…Methamphetamine and methcathinone are psychostimulant drugs with high potential for abuse. In animals, methamphetamine and related drugs are known to damage…”
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