Search Results - "Yohda, M"
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Effect of antipsychotic drugs on DISC1 and dysbindin expression in mouse frontal cortex and hippocampus
Published in Journal of Neural Transmission (01-09-2006)“…Altered expression of Disrupted-In-Schizophrenia-1 (DISC1) and dysbindin (DTNBP1), susceptibility genes for schizophrenia, in schizophrenic brain has been…”
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StHsp14.0, a small heat shock protein of Sulfolobus tokodaii strain 7, protects denatured proteins from aggregation in the partially dissociated conformation
Published in Journal of biochemistry (Tokyo) (01-10-2011)“…The small heat shock protein (sHsp), categorized into a class of molecular chaperones, binds and stabilizes denatured proteins for the purpose of preventing…”
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Post-translational modification is essential for catalytic activity of nitrile hydratase
Published in Protein science (01-05-2000)“…Nitrile hydratase from Rhodococcus sp. N-771 is an αβ heterodimer with a nonheme ferric iron in the catalytic center. In the catalytic center, αCys112 and…”
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Adaptation of a hyperthermophilic group II chaperonin to relatively moderate temperatures
Published in Protein engineering, design and selection (01-05-2010)“…Group II chaperonins exist in archaea and the eukaryotic cytosol, and mediate protein folding in an ATP-dependent manner. We have been studying the reaction…”
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Functional Expression of Nitrile Hydratase in Escherichia coli: Requirement of a Nitrile Hydratase Activator and Post-Translational Modification of a Ligand Cysteine
Published in Journal of biochemistry (Tokyo) (01-04-1999)“…The nitrile hydratase (NHase) from Rhodococcus sp. N-771 is a photoreactive enzyme that is inactivated on nitrosylation of the non-heme iron center and…”
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Arginine 56 mutation in the β subunit of nitrile hydratase: importance of hydrogen bonding to the non-heme iron center
Published in Journal of inorganic biochemistry (01-07-2000)“…Arginine 56 in the β subunit (βArg56) of the iron-containing nitrile hydratase (NHase), one of the strongly conserved residues within the NHase family, is…”
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Novel CYP2C19 629c>a mutant gene detection in Japanese subjects and estimation of its effect on conformation
Published in Drug discoveries & therapeutics (01-12-2010)“…Gene polymorphism is considered to be one of the causes of poor metabolism (PM), and approximately 20 mutants have been reported for CYP2C19 thus far. In our…”
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Multipurpose robot for automated cycle sequencing
Published in BioTechniques (01-03-2003)“…Paramagnetic beads have the superior advantages of easy separation and resuspension by controlling the magnetic filed. Previously, we have developed Magtration…”
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FtsH Recognizes Proteins with Unfolded Structure and Hydrolyzes the Carboxyl Side of Hydrophobic Residues
Published in Journal of biochemistry (Tokyo) (01-05-2000)“…FtsH of Escherichia coli is an essential membrane-integrated ATP-dependent protease. We cloned a gene for an FtsH homolog (T.FtsH) from Thermos thermophilus…”
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Crystallization and preliminary X-ray analysis of aspartate racemase from Pyrococcus horikoshii OT3
Published in Acta crystallographica. Section D, Biological crystallography. (01-11-2001)“…Aspartate racemase from Pyrococcus horikoshii OT3 (P. AspR) has been crystallized in three crystal forms by the sitting‐drop vapour‐diffusion method. The…”
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Properties of aspartate racemase, a pyridoxal 5'-phosphate-independent amino acid racemase
Published in The Journal of biological chemistry (15-09-1992)“…Aspartate racemase from Streptococcus thermophilus contains no pyridoxal 5'-phosphate or other cofactors such as FAD, NAD+, and metal ions. It was affected by…”
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Gene of Heat Shock Protein of Sulfur-Dependent Archaeal Hyperthermophile Desulfurococcus
Published in Biochemical and biophysical research communications (14-09-1995)“…To elucidate thermoresistance, a gene of a hyperthermophilic heat shock protein (HHSP) was isolated from the hyperthermophile Desulfurococcus strain SY which…”
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Chaperonin-mediated stabilization and ATP-triggered release of semiconductor nanoparticles
Published in Nature (London) (05-06-2003)“…Various properties of semiconductor nanoparticles, including photoluminescence and catalytic activity, make these materials attractive for a range of…”
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Structure of Thiocyanate Hydrolase: A New Nitrile Hydratase Family Protein with a Novel Five-coordinate Cobalt(III) Center
Published in Journal of molecular biology (09-03-2007)“…Thiocyanate hydrolase (SCNase) of Thiobacillus thioparus THI115 is a cobalt(III)-containing enzyme catalyzing the degradation of thiocyanate to carbonyl…”
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Solid-phase nested deletion: a new subcloning-less method for generating nested deletions
Published in DNA research (31-08-1995)“…We have developed a new subcloning-less method for generating nested deletions which we have termed Solid-Phase Nested Deletion. The basic procedure for this…”
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Goniothalamin enhances the ATPase activity of the molecular chaperone Hsp90 but inhibits its chaperone activity
Published in Journal of biochemistry (Tokyo) (01-03-2015)“…Hsp90 is an ATP-dependent molecular chaperone that is involved in important cellular pathways such as signal transduction pathways. It is a potential cancer…”
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Performance validation of a functionally distributed energy management architecture
Published in IEEE transactions on power systems (01-05-1992)“…The authors propose a functionally distributed computer (FDS) system for an energy management system (EMS) and a large-scale supervisory control and data…”
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Structure and Molecular Dynamics Simulation of Archaeal Prefoldin: The Molecular Mechanism for Binding and Recognition of Nonnative Substrate Proteins
Published in Journal of molecular biology (29-02-2008)“…Prefoldin (PFD) is a heterohexameric molecular chaperone complex in the eukaryotic cytosol and archaea with a jellyfish-like structure containing six long…”
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Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms
Published in Journal of molecular biology (30-01-2004)“…The crystal structures of the group II chaperonins consisting of the α subunit with amino acid substitutions of G65C and/or I125T from the hyperthermophilic…”
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