Search Results - "Yogo, Yuya"

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  1. 1

    Comparison of the stability of CYP105A1 and its variants engineered for production of active forms of vitamin D by Takita, Teisuke, Sakuma, Hiro, Ohashi, Ren, Nilouyal, Somaye, Nemoto, Sho, Wada, Moeka, Yogo, Yuya, Yasuda, Kaori, Ikushiro, Shinichi, Sakaki, Toshiyuki, Yasukawa, Kiyoshi

    “…CYP105A1 from Streptomyces griseolus converts vitamin D3 to its biologically active form, 1α,25-dihydroxy vitamin D3. R73A/R84A mutation enhanced the 1α- and…”
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    Journal Article
  2. 2

    Metabolism of non-steroidal anti-inflammatory drugs (NSAIDs) by Streptomyces griseolus CYP105A1 and its variants by Yogo, Yuya, Yasuda, Kaori, Takita, Teisuke, Yasukawa, Kiyoshi, Iwai, Yuichiro, Nishikawa, Miyu, Sugimoto, Hiroshi, Ikushiro, Shinichi, Sakaki, Toshiyuki

    Published in Drug metabolism and pharmacokinetics (01-08-2022)
    “…In the field of drug development, technology for producing human metabolites at a low cost is required. In this study, we explored the possibility of using…”
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    Journal Article
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  4. 4

    Production of an active form of vitamin D 2 by genetically engineered CYP105A1 by Yasuda, Kaori, Yogo, Yuya, Sugimoto, Hiroshi, Mano, Hiroki, Takita, Teisuke, Ohta, Miho, Kamakura, Masaki, Ikushiro, Shinichi, Yasukawa, Kiyoshi, Shiro, Yoshitsugu, Sakaki, Toshiyuki

    “…Our previous studies revealed that CYP105A1 can convert vitamin D (VD3) to its active form, 1α,25-dihydroxyvitamin D (1,25D3). Site-directed mutagenesis of…”
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    Journal Article
  5. 5

    Production of an active form of vitamin D2 by genetically engineered CYP105A1 by Yasuda, Kaori, Yogo, Yuya, Sugimoto, Hiroshi, Mano, Hiroki, Takita, Teisuke, Ohta, Miho, Kamakura, Masaki, Ikushiro, Shinichi, Yasukawa, Kiyoshi, Shiro, Yoshitsugu, Sakaki, Toshiyuki

    “…Our previous studies revealed that CYP105A1 can convert vitamin D3 (VD3) to its active form, 1α,25-dihydroxyvitamin D3 (1,25D3). Site-directed mutagenesis of…”
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    Journal Article
  6. 6

    Sequential hydroxylation of vitamin D2 by a genetically engineered CYP105A1 by Hayashi, Keiko, Yasuda, Kaori, Yogo, Yuya, Takita, Teisuke, Yasukawa, Kiyoshi, Ohta, Miho, Kamakura, Masaki, Ikushiro, Shinichi, Sakaki, Toshiyuki

    “…Our previous studies revealed that the double variants of CYP105A1— R73A/R84A and R73V/R84A—show high levels of activity with respect to conversion of vitamin…”
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    Journal Article