Search Results - "Yodo, Mitsuaki"
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Homology Modeling of Gelatinase Catalytic Domains and Docking Simulations of Novel Sulfonamide Inhibitors
Published in Journal of medicinal chemistry (20-05-1999)“…Three-dimensional models for the catalytic domain of gelatinases (MMP-9 and -2) have been constructed based on the X-ray crystal structure of MMP-3…”
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A platform for designing HIV integrase inhibitors. Part 1: 2-Hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores
Published in Bioorganic & medicinal chemistry (15-12-2006)“…A novel class of HIV integrase inhibitors and a critical pharmacophore model useful for designing other classes of inhibitors. We present a novel series of HIV…”
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Synthesis of Methyl 2, 3-Dihydro-2-benzofurancarboxylates from o-Allylphenols via 2-(Phenylthio-methyl)-2, 3-dihydrobenzofurans
Published in Chemical & pharmaceutical bulletin (1989)“…A method for synthesizing methyl 2, 3-dihydro-2-benzofurancarboxylates from o-allylphenols is described. The reaction of 6-allyl-2, 3-dichlorophenol (3) with…”
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Optical Resolution and Chiral Synthesis of Methyl 6, 7-Dichloro-2, 3-dihydrobenzo[b]furan-2-carboxylate
Published in Chemical & pharmaceutical bulletin (1988)“…Optical isomers of methyl 6, 7-dichloro-2, 3-dihydrobenzo[b]furan-2-carboxylate (2) were prepared by means of both optical resolution and chiral synthesis. The…”
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Studies on Uricosuric Diuretics. I. 6, 7-Dichloro-5-sulfamoyl-2, 3-dihydrobenzofuran-2-carboxylic Acids
Published in Chemical & pharmaceutical bulletin (1987)“…2, 3-Dihydrobenzofuran derivatives having various sulfamoyl groups at the 5-position were synthesized and tested for oral diuretic and saluretic activities in…”
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Studies on Uricosuric Diuretics. II. 6, 7-Dichloro-4-nitro-, 6, 7-Dichloro-4-sulfamoyl-and 6, 7-Dichloro-4-acyl-2, 3-dihydrobenzofuran-2-carboxylic Acids
Published in Chemical & pharmaceutical bulletin (1987)“…2, 3-Dihydrobenzofuran-2-carboxylic acids substituted with electronegative nitro, acyl and sulfamoyl groups at the 4-position were synthesized and tested for…”
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Multiple binding modes for the receptor-bound conformations of cyclic AII agonists
Published in Journal of medicinal chemistry (25-06-1993)“…Angiotensin II, Asp-Arg-Val-Tyr-His-Pro-Phe, binds its receptor with a postulated turn centered at residue four. Analogs of angiotensin II which contain a…”
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The utility of side-chain cyclization in determining the receptor-bound conformation of peptides: cyclic tripeptides and angiotensin II
Published in Biopolymers (01-11-1992)“…The effect of side-chain cyclization on accessible backbone conformations of tripeptides, X-Ala-Y (X and/or Y = Cys, Hcy (Hcy: homocysteine), cis…”
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Novel Bicycloannulation via Tandem Vinylation and Intramolecular Diels-Alder Reaction of Five-Membered Heterocycles
Published in Heterocycles (1985)Get full text
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