Search Results - "Yodis, L P"
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In vitro metabolism of the novel antiinflammatory agent 6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole
Published in Drug metabolism and disposition (01-09-1990)“…6-(4'-Fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thia zole (SK&F 86002) is a dual inhibitor of arachidonic acid metabolism which has therapeutic…”
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2
Pharmacokinetics and metabolism of SK&F 86002 in male and female Sprague-Dawley rats
Published in Drug metabolism and disposition (01-03-1989)“…Several pharmacokinetic parameters for SK&F 86002 [6-(4'-fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo(2,1-b)-thia zole] and its metabolites (sulfoxide,…”
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3
Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation
Published in Analytical biochemistry (01-04-1988)“…An assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection, has been developed. Conditions were…”
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4
Comparative biochemical and morphometric changes associated with induction of the hepatic mixed function oxidase system in the rat
Published in Toxicologic pathology (01-01-1991)“…This study characterized the induction of the rat hepatic cytochrome P-450-dependent mixed function oxidase system by SK&F 86002…”
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