Search Results - "Yoden, Eiji"

A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II by Sonoda, Hiroyuki, Morimoto, Hideto, Yoden, Eiji, Koshimura, Yuri, Kinoshita, Masafumi, Golovina, Galina, Takagi, Haruna, Yamamoto, Ryuji, Minami, Kohtaro, Mizoguchi, Akira, Tachibana, Katsuhiko, Hirato, Tohru, Takahashi, Kenichi

“…Mucopolysaccharidosis II (MPS II) is an X-linked recessive lysosomal storage disease caused by mutations in the iduronate-2-sulfatase (IDS) gene. Since IDS…”
Get full text

Clearance of heparan sulfate in the brain prevents neurodegeneration and neurocognitive impairment in MPS II mice by Morimoto, Hideto, Kida, Sachiho, Yoden, Eiji, Kinoshita, Masafumi, Tanaka, Noboru, Yamamoto, Ryuji, Koshimura, Yuri, Takagi, Haruna, Takahashi, Kenichi, Hirato, Tohru, Minami, Kohtaro, Sonoda, Hiroyuki

“…Mucopolysaccharidosis II (MPS II), a lysosomal storage disease caused by mutations in iduronate-2-sulfatase (IDS), is characterized by a wide variety of…”
Get full text

Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II by Yamamoto, Ryuji, Yoden, Eiji, Tanaka, Noboru, Kinoshita, Masafumi, Imakiire, Atsushi, Hirato, Tohru, Minami, Kohtaro

“…Pabinafusp alfa is a fusion protein comprising a humanized anti-human transferrin receptor (TfR) antibody and human iduronate-2-sulfatase. It was developed as…”
Get full text

Non-clinical evaluation of JR-051 as a biosimilar to agalsidase beta for the treatment of Fabry disease by Morimoto, Hideto, Ito, Yae, Yoden, Eiji, Horie, Masato, Tanaka, Noboru, Komurasaki, Yoshikazu, Yamamoto, Ryuji, Mihara, Kazutoshi, Minami, Kohtaro, Hirato, Tohru

“…Fabry disease (FD) is an X-linked lysosomal storage disease. It is caused by deficiency of the enzyme α-galactosidase A (α-Gal A), which leads to excessive…”
Get full text

Enzyme replacement with transferrin receptor-targeted α-L-iduronidase rescues brain pathology in mucopolysaccharidosis I mice by Kida, Sachiho, Koshimura, Yuri, Yoden, Eiji, Yoshioka, Aya, Morimoto, Hideto, Imakiire, Atsushi, Tanaka, Noboru, Tanaka, Satowa, Mori, Ayaka, Ito, Jun, Inoue, Asuka, Yamamoto, Ryuji, Minami, Kohtaro, Hirato, Tohru, Takahashi, Kenichi, Sonoda, Hiroyuki

“…Mucopolysaccharidosis I (MPS I), a lysosomal storage disease caused by dysfunction of α-L-iduronidase (IDUA), is characterized by the deposition of dermatan…”
Get full text

Transferrin Receptor-Targeted Iduronate-2-sulfatase Penetrates the Blood-Retinal Barrier and Improves Retinopathy in Mucopolysaccharidosis II Mice by Imakiire, Atsushi, Morimoto, Hideto, Suzuki, Hidehiko, Masuda, Tomomi, Yoden, Eiji, Inoue, Asuka, Morioka, Hiroki, Konaka, Takashi, Mori, Ayaka, Shirasaka, Ryoji, Kato, Ryo, Hirato, Tohru, Sonoda, Hiroyuki, Minami, Kohtaro

“…Mucopolysaccharidoses (MPSs) make up a group of lysosomal storage diseases characterized by the aberrant accumulation of glycosaminoglycans throughout the…”
Get full text

Recovery of retinal function in MPS II mice by treatment with pabinafusp alfa by Imakiire, Atsushi, Morimoto, Hideto, Suzuki, Hidehiko, Masuda, Tomomi, Yoden, Eiji, Inoue, Asuka, Morioka, Hiroki, Konaka, Takashi, Mori, Ayaka, Shirasaka, Ryoji, Kato, Ryo, Hirato, Toru, Sonoda, Hiroyuki, Minami, Kohtaro

Get full text

A fusion protein of anti-human transferrin receptor antibody and alfa-L-fucosidase 1 is a prospective candidate for the treatment of the symptoms in CNS and visceral tissues of fucosidosis by Yoden, Eiji, Onouchi, Takashi, Fujiyama, Saki, Kida, Sachiho, Hashimoto, Hidehiko, Machida, Wataru, Tanaka, Noboru, Morimoto, Hideto, Shibasaki, Tadao, Minami, Kohtaro, Hirato, Tohru, Sonoda, Hiroyuki, Takahashi, Kenichi

Get full text

Life-span extension in Krabbe disease mice by treatment with a transferrin receptor-targeted galactocerebrosidase by Imakiire, Atsushi, Sugano, Yasunori, Shibasaki, Tadao, Yoden, Eiji, Miyauchi, Kazuki, Yamamoto, Ryuji, Morimoto, Hideto, Minami, Kohtaro, Hirato, Tohru, Sonoda, Hiroyuki, Takahashi, Kenichi

Get full text

The characterization of mouse model of mucopolysaccharidosis type II by Kinoshita, Masafumi, Morimoto, Hideto, Yoden, Eiji

Get full text

Reduction of heparan sulfate in the brain by pabinafusp alfa results in prevention of neurodegeneration and neurocognitive impairment in a mouse model of mucopolysaccharidosis type II by Morimoto, Hideto, Kida, Sachiho, Yoden, Eiji, Kinoshita, Masafumi, Tanaka, Noboru, Yamamoto, Ryuji, Koshimura, Yuri, Takagi, Haruna, Takahashi, Kenichi, Hirato, Tohru, Minami, Kohtaro, Sonoda, Hiroyuki

Get full text

Novel quantification methods for globotriaosylceramide and globotriaosylsphingosine as biomarkers of Fabry disease by Tanaka, Noboru, Morimoto, Hideto, Yoden, Eiji, Yamamoto, Ryuji

Get full text

Blood-brain barrier-penetrating iduronate-2-sulfatase reduces brain glycosaminoglycans in mouse model of mucopolysaccharidosis type II by Sonoda, Hiroyuki, Morimoto, Hideto, Yoden, Eiji, Koshimura, Yuri, Kinoshita, Masafumi, Golovina, Galina, Takagi, Haruna, Yamamoto, Ryuji, Minami, Kohtaro, Tachibana, Katsuhiko, Hirato, Tohru, Takahashi, Kenichi

Get full text