Methods for magnetically labeling stem and other cells for detection by in vivo magnetic resonance imaging

Methods for magnetically labeling stem and other cells for detection by in vivo magnetic resonance imaging

Superparamagnetic iron oxide (SPIO) nanoparticles are being used for intracellular magnetic labeling of stem cells and other cells in order to monitor cell trafficking by magnetic resonance imaging (MRI) as part of cellular-based repair, replacement and treatment strategies. This review focuses on t...

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Bibliographic Details
Published in:Cytotherapy (Oxford, England) Vol. 6; no. 6; pp. 621 - 625
Main Authors: Frank, J.A., Anderson, S.A., Kalsih, H., Jordan, E.K., Lewis, B.K., Yocum, G.T., Arbab, A.S.
Format: Journal Article
Language:English
Published: England Elsevier Inc 01-12-2004
Informa UK Ltd
Subjects:
Animals
Clinical Trials as Topic
Contrast Media - chemistry
Contrast Media - metabolism
Dextrans
Ferrosoferric Oxide
Humans
Iron - chemistry
Iron - metabolism
Magnetic Resonance Imaging - methods
Magnetics
Magnetite Nanoparticles
Molecular Probes - chemistry
Molecular Probes - metabolism
Oxides - chemistry
Oxides - metabolism
Staining and Labeling
Stem Cells - cytology
Stem Cells - physiology
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Summary:Superparamagnetic iron oxide (SPIO) nanoparticles are being used for intracellular magnetic labeling of stem cells and other cells in order to monitor cell trafficking by magnetic resonance imaging (MRI) as part of cellular-based repair, replacement and treatment strategies. This review focuses on the various methods for magnetic labeling of stem cells and other mammalian cells and on how to translate experimental results from bench to bedside.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1465-3249
1477-2566
DOI:10.1080/14653240410005267-1