Search Results - "Yock, Adam"
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Adaptive Radiation Therapy (ART) Strategies and Technical Considerations: A State of the ART Review From NRG Oncology
Published in International journal of radiation oncology, biology, physics (15-03-2021)“…The integration of adaptive radiation therapy (ART), or modifying the treatment plan during the treatment course, is becoming more widely available in clinical…”
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Application of an automatic, uncertainty model‐guided, target‐generating algorithm to lung stereotactic body radiotherapy
Published in Medical physics (Lancaster) (01-12-2021)“…Purpose This work evaluated a new radiotherapy target‐generating framework (the αTarget algorithm) for creating internal target volumes for lung SBRT. Methods…”
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Generating amorphous target margins in radiation therapy to promote maximal target coverage with minimal target size
Published in Computer methods and programs in biomedicine (01-11-2018)“…This work provides proof-of-principle for two versions of a heuristic approach that automatically creates amorphous radiation therapy planning target volume…”
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Initial analysis of the dosimetric benefit and clinical resource cost of CBCT‐based online adaptive radiotherapy for patients with cancers of the cervix or rectum
Published in Journal of applied clinical medical physics (01-10-2021)“…Purpose This provides a benchmark of dosimetric benefit and clinical cost of cone‐beam CT‐based online adaptive radiotherapy (ART) technology for cervical and…”
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Empirical analysis of a plan‐of‐the‐day strategy to approximate daily online reoptimization for prostate CBCT‐guided adaptive radiotherapy
Published in Journal of applied clinical medical physics (01-01-2024)“…Purpose Adaptive radiotherapy (ART) can improve the dose delivered to the patient in the presence of anatomic variations. However, the required time, effort,…”
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A comparison of two prospective risk analysis methods: Traditional FMEA and a modified healthcare FMEA
Published in Medical physics (Lancaster) (01-12-2016)“…Purpose: To examine the abilities of a traditional failure mode and effects analysis (FMEA) and modified healthcare FMEA (m-HFMEA) scoring methods by comparing…”
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Mean cardiopulmonary dose and vertebral marrow dose differentially predict lineage-specific leukopenia kinetics during radiotherapy for esophageal cancer
Published in Radiotherapy and oncology (01-11-2020)“…•Hematologic toxicity is known to predict poor outcomes in esophageal cancer (EC).•Off-target radiation during treatment for EC predicts lineage-specific…”
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Triggering daily online adaptive radiotherapy in the pelvis: Dosimetric effects and procedural implications of trigger parameter-value selection
Published in Journal of applied clinical medical physics (01-10-2023)“…Online adaptive radiotherapy (ART) can address dosimetric consequences of variations in anatomy by creating a new plan during treatment. However, ART is time-…”
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Split-Course Adaptive Radioimmunotherapy for Oligometastatic Non-Small Cell Lung Cancer (SiCARIO): A Case Report
Published in Curēus (Palo Alto, CA) (07-09-2024)“…Current treatment paradigms for oligometastatic non-small cell lung cancer (NSCLC) utilize systemic chemotherapy alone or in combination with immune checkpoint…”
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Prospective treatment plan-specific action limits for real-time intrafractional monitoring in surface image guided radiosurgery
Published in Medical physics (Lancaster) (01-07-2016)“…Purpose: In surface image guided radiosurgery, action limits are created to determine at what point intrafractional motion exhibited by the patient is large…”
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Robustness Analysis for External Beam Radiation Therapy Treatment Plans: Describing Uncertainty Scenarios and Reporting Their Dosimetric Consequences
Published in Practical Radiation Oncology (01-07-2019)“…With external beam radiation therapy, uncertainties in treatment planning and delivery can result in an undesirable dose distribution delivered to the patient…”
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A novel 3D‐printed phantom insert for 4D PET/CT imaging and simultaneous integrated boost radiotherapy
Published in Medical physics (Lancaster) (01-10-2017)“…Purpose To construct a 3D‐printed phantom insert designed to mimic the variable PET tracer uptake seen in lung tumor volumes and a matching dosimetric insert…”
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Technical Note: Using k‐means clustering to determine the number and position of isocenters in MLC‐based multiple target intracranial radiosurgery
Published in Journal of applied clinical medical physics (01-09-2017)“…Purpose To present the k‐means clustering algorithm as a tool to address treatment planning considerations characteristic of stereotactic radiosurgery using a…”
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Investigating the potential of conical scintillation detectors for patient-specific verification of intensity-modulated radiotherapy plans
Published in Physics and imaging in radiation oncology (01-04-2020)“…Conical scintillation detectors are frequently used to measure geometric characteristics of radiotherapy modalities. However, their application to verify…”
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Anisotropic Margin Expansions in 6 Anatomic Directions for Oropharyngeal Image Guided Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-11-2013)“…Purpose The purpose of this work was to determine the expansions in 6 anatomic directions that produced optimal margins considering nonrigid setup errors and…”
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Predicting oropharyngeal tumor volume throughout the course of radiation therapy from pretreatment computed tomography data using general linear models
Published in Medical physics (Lancaster) (01-05-2014)“…Purpose: The purpose of this work was to develop and evaluate the accuracy of several predictive models of variation in tumor volume throughout the course of…”
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Forecasting longitudinal changes in oropharyngeal tumor morphology throughout the course of head and neck radiation therapy
Published in Medical physics (Lancaster) (01-08-2014)“…Purpose: To create models that forecast longitudinal trends in changing tumor morphology and to evaluate and compare their predictive potential throughout the…”
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Employ Piece-wise Optimization
Published in International journal of radiation oncology, biology, physics (01-08-2018)Get full text
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Initial safety assessment of the endoscopically injected oncolytic virus OBP-301 in medically inoperable esophageal cancer: NRG-GI007
Published in Journal of clinical oncology (20-01-2024)“…341 Background: Definitive chemoradiation (CRT) is a standard-of-care for patients (Pts) with medically inoperable esophageal cancer (EC). The NRG/RTOG 0436…”
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NRG Oncology NRG-GI007 trial-in-progress: Phase I study of OBP-301 (Telomelysin) and definitive chemoradiation (CRT) for patients with locally advanced esophageal and gastroesophageal adenocarcinoma who are not candidates for surgery
Published in Journal of clinical oncology (20-01-2021)“…Abstract only TPS262 Background: Definitive CRT is a standard-of-care for patients with medically inoperable esophageal cancer (EC, NEJM 326:1593). The…”
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