Search Results - "Yocca, F"

Effects of the δ opioid agonist AZD2327 upon operant behaviors and assessment of its potential for abuse by Hudzik, T.J., Pietras, M.R., Caccese, R., Bui, K.H., Yocca, F., Paronis, C.A., M.D.B., Swedberg

“…AZD2327 is a brain-penetrant agonist at δ opioid receptors which has antidepressant and anxiolytic properties in a wide array of animal models. As part of the…”
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Lack of apparent receptor reserve at postsynaptic 5-hydroxytryptamine1A receptors negatively coupled to adenylyl cyclase activity in rat hippocampal membranes by Yocca, F D, Iben, L, Meller, E

“…Previous studies have demonstrated the existence of a large receptor reserve for agonists at somatodendritic 5-hydroxytryptamine1A (5-HT1A) serotonin receptors…”
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Phase Shifting of Circadian Rhythms and Depression of Neuronal Activity in the Rat Suprachiasmatic Nucleus by Neuropeptide Y: Mediation by Different Receptor Subtypes by Gribkoff, Valentin K, Pieschl, Rick L, Wisialowski, Todd A, van den Pol, Anthony N, Yocca, Frank D

“…Neuropeptide Y (NPY) has been implicated in the phase shifting of circadian rhythms in the hypothalamic suprachiasmatic nucleus (SCN). Using long-term,…”
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Pharmacology and neurochemistry of nefazodone, a novel antidepressant drug by Taylor, D P, Carter, R B, Eison, A S, Mullins, U L, Smith, H L, Torrente, J R, Wright, R N, Yocca, F D

“…Nefazodone is a new antidepressant drug with a pharmacologic profile distinct from that of the tricyclic, monoamine oxidase inhibitor, and serotonin selective…”
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The structure and signalling properties of 5-HT receptors: an endless diversity? by Martin, G.R, Eglen, R.M, Hamblin, M.W, Hoyer, D, Yocca, F

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Serotonin (5-HT) release in the dorsal raphé and ventral hippocampus : raphé control of somatodendritic and terminal 5-HT release by MATOS, F. F, URBAN, C, YOCCA, F. D

“…Somatodendritic and terminal release of serotonin (5-HT) was investigated by simultaneously measuring extracellular concentrations of 5-HT,…”
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Comparative effects of chronic 8-OH-DPAT, gepirone and ipsapirone treatment on the sensitivity of somatodendritic 5-HT1A autoreceptors by Bohmaker, K, Eison, A S, Yocca, F D, Meller, E

“…Chronic treatment with the full 5-hydroxytryptamine1A (5-HT1A) agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), either by twice daily subcutaneous…”
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Neurochemistry and neurophysiology of buspirone and gepirone: interactions at presynaptic and postsynaptic 5-HT1A receptors by Yocca, F D

“…Preclinical neurochemical studies indicate that buspirone and gepirone bind selectively to presynaptic (dorsal raphe) and postsynaptic (hippocampus, cortex)…”
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Effect of chronic administration of antidepressant drugs on 5-HT2-mediated behavior in the rat following noradrenergic or serotonergic denervation by EISON, A. S, YOCCA, F. D, GIANUTSOS, G

“…Chronic (14 day) administration of several pharmacologically-distinct antidepressant drugs resulted in marked reductions in the serotonin2 (5-HT2)-mediated…”
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Lack of 5-hydroxytryptamine1A-mediated inhibition of adenylyl cyclase in dorsal raphe of male and female rats by Clarke, W P, Yocca, F D, Maayani, S

“…In the rat hippocampus, 5-hydroxytryptamine (5-HT)1A receptors couple to two independent effector mechanisms, the inhibition of adenylyl cyclase activity and…”
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Cloning and characterization of the rat 5-HT5B receptor : evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes by WISDEN, W, PARKER, E. M, MAHLE, C. D, GRISEL, D. A, NOWAK, H. P, YOCCA, F. D, FELDER, C. C, SEEBURG, P. H, VOIGT, M. M

“…A gene encoding a novel G protein-coupled 5-hydroxytryptamine (5-HT) receptor, termed 5-HT5B, was cloned. The ligand binding profile of this receptor is…”
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BMY 7378, a buspirone analog with high affinity, selectivity and low intrinsic activity at the 5-HT1A receptor in rat and guinea pig hippocampal membranes by Yocca, F D, Hyslop, D K, Smith, D W, Maayani, S

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5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus by MATOS, F. F, KORPINEN, C, YOCCA, F. D

“…BMY-14802 (BMS-181100; alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol monohydrochloride) is a sigma receptor antagonist with potential…”
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[3H]‐5‐carboxamidotryptamine labels 5‐HT1D binding sites in bovine substantia nigra by Nowak, Henry P., Mahle, Cathy D., Yocca, Frank D.

“…1 [3H]‐5‐hydroxytryptamine (5‐HT) has been shown to radiolabel at least five types of 5‐HT binding sites in mammalian brain tissue, 5‐HT1A, 5‐HT1B, 5‐HT1C,…”
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[3H]5-carboxamidotryptamine labels multiple high affinity 5-HT1D-like sites in guinea pig brain by Mahle, C D, Nowak, H P, Mattson, R J, Hurt, S D, Yocca, F D

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Characterization of human 5-HT1 receptors expressed in Sf9 insect cells by Parker, E M, Grisel, D A, Iben, L G, Nowak, H P, Mahle, C D, Yocca, F D, Gaughan, G T

“…Four human 5-HT receptor subtypes (5-HT1A, 5-HT1D alpha, 5-HT1D beta and 5-HT1E) have been expressed in Sf9 insect cells. All four human 5-hydroxytryptamine…”
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Noradrenergic denervation alters serotonin2-mediated behavior but not serotonin2 receptor number in rats: modulatory role of beta adrenergic receptors by Eison, A S, Yocca, F D, Gianutsos, G

“…Recent behavioral evidence suggests that enhancement of noradrenergic neurotransmission may alter the functional sensitivity of serotonin2 (5-HT2) receptors in…”
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8-OH-DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats by Yocca, F D, Wright, R N, Margraf, R R, Eison, A S

“…Behavioral syndromes mediated by serotonergic mechanisms may reflect interactions between distinct effects initiated by specific 5-HT receptors, such as the…”
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Reduction in cortical 5HT2 receptor sensitivity after continuous gepirone treatment by Eison, A S, Yocca, F D

“…Continuous administration (28 days) of gepirone, a potential anxiolytic, decreased rat cortical serotonin type 2 (5HT2) receptor density by 17 percent and…”
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BMS-181885, a 5-HT1B/1D receptor ligand, in experimental models predictive of antimigraine activity and coronary side-effect potential by SAXENA, P. R, DE VRIES, P, HEILIGERS, J. P. C, BAX, W. A, MAASSENVANDENBRINK, A, YOCCA, F. D

“…Many acutely acting antimigraine drugs have the ability to constrict porcine arteriovenous anastomoses as well as the human isolated coronary artery. These two…”
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