Search Results - "Yizheng Yao"

Simultaneous downregulation of miR-21 and upregulation of miR-7 has anti-tumor efficacy by Bhere, Deepak, Arghiani, Nahid, Lechtich, Esther Revai, Yao, Yizheng, Alsaab, Sarah, Bei, Fengfeng, Matin, Maryam M., Shah, Khalid

“…Dysregulation of miRNA expression has been implicated in cancer. Numerous strategies have been explored to modulate miR but sub-optimal delivery and inability…”
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Author Correction: Simultaneous downregulation of miR-21 and upregulation of miR-7 has anti-tumor efficacy by Bhere, Deepak, Arghiani, Nahid, Lechtich, Esther Revai, Yao, Yizheng, Alsaab, Sarah, Bei, Fengfeng, Matin, Maryam M., Shah, Khalid

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Designing and optimizing AAV-mediated gene therapy for neurodegenerative diseases: from bench to bedside by Xu, Liang, Yao, Shun, Ding, Yifan Evan, Xie, Mengxiao, Feng, Dingqi, Sha, Pengfei, Tan, Lu, Bei, Fengfeng, Yao, Yizheng

“…Recombinant adeno-associated viruses (rAAVs) have emerged as an attractive tool for gene delivery, and demonstrated tremendous promise in gene therapy and gene…”
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AAV for Gene Therapy in Ocular Diseases: Progress and Prospects by He, Xiaoyu, Fu, Yidian, Ma, Liang, Yao, Yizheng, Ge, Shengfang, Yang, Zhi, Fan, Xianqun

“…Owing to the promising therapeutic effect and one-time treatment advantage, gene therapy may completely change the management of eye diseases, especially…”
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Glioblastoma-Derived Extracellular Vesicles Facilitate Transformation of Astrocytes via Reprogramming Oncogenic Metabolism by Zeng, Ailiang, Wei, Zhiyun, Rabinovsky, Rosalia, Jun, Hyun Jung, El Fatimy, Rachid, Deforzh, Evgeny, Arora, Ramil, Yao, Yizheng, Yao, Shun, Yan, Wei, Uhlmann, Erik J., Charest, Alain, You, Yongping, Krichevsky, Anna M.

“…Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived…”
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A blood-brain barrier-penetrant AAV gene therapy improves neurological function in symptomatic mucolipidosis IV mice by Sangster, Madison L., Bishop, Martha M., Yao, Yizheng, Feitor, Jessica F., Shahriar, Sanjid, Miller, Maxwell E., Chekuri, Anil K., Budnik, Bogdan, Bei, Fengfeng, Grishchuk, Yulia

“…Mucolipidosis IV (MLIV) is a rare, autosomal recessive, lysosomal disease characterized by intellectual disability, motor deficits, and progressive vision…”
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Preliminary study and bioinformatics analysis on the potential role of CagQ in type IV secretion system of H.pylori by Yao, Yizheng, Shen, Yixin, Zhu, Linqi, Ni, Ying, Wang, Hua, Shao, Shihe

“…Helicobacter pylori (H.pylori), is a major causative agent of chronic gastritis, gastric carcinoma and duodenal ulcer. Remarkably, H.pylori carries…”
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BBB-crossing adeno-associated virus vector: An excellent gene delivery tool for CNS disease treatment by Chen, Wenli, Yao, Shun, Wan, Jie, Tian, Yu, Huang, Lan, Wang, Shanshan, Akter, Farhana, Wu, Yinqiu, Yao, Yizheng, Zhang, Xiaochun

“…The presence of the blood-brain barrier (BBB) remains a challenge in the treatment of central nervous system (CNS) diseases, as it hinders the infiltration of…”
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Engineering, delivery, and biological validation of artificial microRNA clusters for gene therapy applications by Bhaskaran, Vivek, Yao, Yizheng, Bei, Fengfeng, Peruzzi, Pierpaolo

“…The cellular machinery regulating microRNA biogenesis and maturation relies on a small number of simple steps and minimal biological requirements and is…”
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Enhanced Oxygen Evolution of a Magnetic Catalyst by Regulating Intrinsic Magnetism by Ma, Yibing, Wang, Tong, Sun, Xuhui, Yao, Yizheng, Chen, Huan, Wu, Gan, Zhang, Chao, Qin, Yiqiang

“…The promotion of magnetic field on catalytic performance has attracted extensive attention. However, little research has been reported on the performance of…”
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Different T-cell subsets in glioblastoma multiforme and targeted immunotherapy by Wang, Hongsheng, Zhou, Huangao, Xu, Jianing, Lu, Yunpeng, Ji, Xiaoyun, Yao, Yizheng, Chao, Hou, Zhang, Jun, Zhang, Xiaochun, Yao, Shun, Wu, Yinqiu, Wan, Jie

“…Glioblastoma multiforme (GBM) is a brain tumor with a high mortality rate. Surgical resection combined with radiotherapy and chemotherapy is the standard…”
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Challenges in adeno-associated virus-based treatment of central nervous system diseases through systemic injection by Huang, Lan, Wan, Jie, Wu, Yinqiu, Tian, Yu, Yao, Yizheng, Yao, Shun, Ji, Xiaoyun, Wang, Shengjun, Su, Zhaoliang, Xu, Huaxi

“…Adeno-associated virus (AAV) vector, an excellent gene therapy vector, has been widely used in the treatment of various central nervous system (CNS) diseases…”
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The role of Notch signaling in gastric carcinoma: molecular pathogenesis and novel therapeutic targets by Yao, Yizheng, Ni, Ying, Zhang, Jiawen, Wang, Hua, Shao, Shihe

“…Notch signaling, an evolutionarily conserved signaling cascade system, is involved in promoting the progression of different types of cancers. Within the past…”
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Perfect Talbot self-imaging effect of aperiodic gratings by Yao, Yizheng, Sun, Xuhui, Ma, Yibing, Wang, Tong, Wu, Gan, Chen, Huan, Gao, Bing, Wang, Chenglong, Wu, Hao, Zhang, Chao, Qin, Yiqiang

“…We propose and investigate a class of aperiodic grating structure which can achieve perfect Talbot effect under certain conditions. The aperiodic grating…”
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Microarray analysis of Long non-coding RNA expression profiles in human gastric cells and tissues with Helicobacter pylori Infection by Zhu, Hong, Wang, Qiang, Yao, Yizheng, Fang, Jian, Sun, Fengying, Ni, Ying, Shen, Yixin, Wang, Hua, Shao, Shihe

“…Although Helicobacter pylori (H.pylori) is the dominant gastrointestinal pathogen, the genetic and molecular mechanisms underlying H.pylori-related diseases…”
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Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood–brain barrier in rodents and primates by Yao, Yizheng, Wang, Jun, Liu, Yi, Qu, Yuan, Wang, Kaikai, Zhang, Yang, Chang, Yuxin, Yang, Zhi, Wan, Jie, Liu, Junfeng, Nakashima, Hiroshi, Lawler, Sean E., Chiocca, E. Antonio, Cho, Choi-Fong, Bei, Fengfeng

“…The development of gene therapies for the treatment of diseases of the central nervous system has been hindered by the limited availability of adeno-associated…”
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IL1RN mediates the suppressive effect of methionine deprivation on glioma proliferation by Wang, Kaikai, Liu, Huailei, Liu, Jiaqi, Wang, Xiaoxiong, Teng, Lei, Zhang, Jun, Liu, Yi, Yao, Yizheng, Wang, Jun, Qu, Yuan, Chen, Xin, Peng, Fei, Liu, Hongbo, Wang, Ning, Zhong, Yingqiang, Hou, Xu, Jiang, Haiping, Beylerli, Ozal, Liao, Xiang, Zhang, Xinjian, Zhang, Xu, Zhang, Xiangtong, Zhao, Shiguang

“…Metabolic abnormality is one of the hallmarks of cancer cells, and limiting material supply is a potential breakthrough approach for cancer treatment…”
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Helicobacter pylori CagI is associated with the stability of CagA by Wang, Hua, Yao, Yizheng, Ni, Bin, Shen, Yixin, Wang, Xiaochun, Shen, Hongxing, Shao, Shihe

“…The type Ⅳ secretion system (T4SS) of H. pylori encoded by cag pathogenicity island mediates the injection of the toxin CagA, which is considered as a paradigm…”
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Association of Preeclampsia with Incident Dementia and Alzheimer’s Disease among Women in the Framingham Offspring Study by Wang, Kanran, Guo, Kaining, Ji, Z., Liu, Y., Chen, F., Wu, S., Zhang, Q., Yao, Yizheng, Zhou, Qin

“…Background This study aimed to investigate the association between preeclampsia and all-cause dementia and Alzheimer’s Disease (AD). Methods This…”
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A framework for testing distributed software components by Yizheng Yao, Yingxu Wang

“…Component-based software engineering is an influential trend in software engineering. Adopting component-based techniques, a system can be constructed by…”
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