Search Results - "Yiu, Glenn"

Statistical Issues on Evaluating Association Between the Cilioretinal Artery and Age-Related Macular Degeneration-Reply by Snyder, Kiersten, Yiu, Glenn C

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Effect of Anti–Vascular Endothelial Growth Factor Therapy on Choroidal Thickness in Diabetic Macular Edema by Yiu, Glenn, Manjunath, Varsha, Chiu, Stephanie J, Farsiu, Sina, Mahmoud, Tamer H

“…Purpose To determine the effect of anti–vascular endothelial growth factor (VEGF) therapy on choroidal thickness in eyes with diabetic macular edema (DME)…”
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Genomic Disruption of VEGF-A Expression in Human Retinal Pigment Epithelial Cells Using CRISPR-Cas9 Endonuclease by Yiu, Glenn, Tieu, Eric, Nguyen, Anthony T, Wong, Brittany, Smit-McBride, Zeljka

“…To employ type II clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 endonuclease to suppress ocular angiogenesis by genomic disruption of…”
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Retinal detachment in severe myopia by Moisseiev, Elad, MD, Yiu, Glenn, Dr

“…Separation of the liquefied vitreous from the back of the eye--known as a posterior vitreous detachment--can lead to a retinal break or tear that allows fluid…”
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In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques by Yiu, Glenn, Tieu, Eric, Munevar, Christian, Wong, Brittany, Cunefare, David, Farsiu, Sina, Garzel, Laura, Roberts, Jeffrey, Thomasy, Sara M.

“…Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of…”
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Relationship of Retinal Vessel Caliber with Age-Related Macular Degeneration by Toulouie, Sara, Chang, Sean, Pan, Julia, Snyder, Kiersten, Yiu, Glenn

“…Purpose. Evaluate the relationship between retinal vascular caliber and age-related macular degeneration (AMD) severity or progression. Methods. A…”
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Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates by Yiu, Glenn, Chung, Sook Hyun, Mollhoff, Iris N., Nguyen, Uyen Tu, Thomasy, Sara M., Yoo, Jesse, Taraborelli, Donna, Noronha, Glenn

“…Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the…”
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Goji Berry Intake Increases Macular Pigment Optical Density in Healthy Adults: A Randomized Pilot Trial by Li, Xiang, Holt, Roberta R, Keen, Carl L, Morse, Lawrence S, Yiu, Glenn, Hackman, Robert M

“…Age-related macular degeneration (AMD) is the third leading cause of blindness worldwide. Macular pigment optical density (MPOD), a biomarker for AMD, is a…”
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A Review of Innovations in Rhegmatogenous Retinal Detachment Surgical Techniques by Loewenstein, Anat, Yiu, Glenn, Moshiri, Ala, Nemet, Achia, Moisseiev, Elad

“…Rhegmatogenous retinal detachment (RRD) requires surgical intervention for its repair. There are variable techniques used for this purpose, and they are all…”
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Macular Fluid Reduces Reproducibility of Choroidal Thickness Measurements on Enhanced Depth Optical Coherence Tomography by Wong, Sophia S., Vuong, Vivian S., Cunefare, David, Farsiu, Sina, Moshiri, Ala, Yiu, Glenn

“…To determine if different types of retinal fluid in the central macula affect the reproducibility of choroidal thickness (CT) measurements on enhanced depth…”
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SUPRACHOROIDAL SPACE INJECTION TECHNIQUE: Expert Panel Guidance by Wykoff, Charles C, Avery, Robert L, Barakat, Mark R, Boyer, David S, Brown, David M, Brucker, Alexander J, Cunningham, Jr, Emmett T, Heier, Jeffrey S, Holekamp, Nancy M, Kaiser, Peter K, Khanani, Arshad M, Kim, Judy E, Demirci, Hakan, Regillo, Carl D, Yiu, Glenn C, Ciulla, Thomas A

“…To develop professional guidelines for best practices for suprachoroidal space (SCS) injection, an innovative technique for retinal therapeutic delivery, based…”
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Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections by Yiu, Glenn, Wang, Zhe, Munevar, Christian, Tieu, Eric, Shibata, Bradley, Wong, Brittany, Cunefare, David, Farsiu, Sina, Roberts, Jeffrey, Thomasy, Sara M.

“…Nonhuman primates are important preclinical models of retinal diseases because they uniquely possess a macula similar to humans. Ocular imaging technologies…”
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CRISPR-based VEGF suppression using paired guide RNAs for treatment of choroidal neovascularization by Chung, Sook Hyun, Sin, Tzu-Ni, Dang, Brian, Ngo, Taylor, Lo, Therlinder, Lent-Schochet, Daniella, Meleppat, Ratheesh K., Zawadzki, Robert J., Yiu, Glenn

“…Clustered regularly interspaced short palindromic repeats (CRISPR)-based genomic disruption of vascular endothelial growth factor A (Vegfa) with a single gRNA…”
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Teleophthalmology provides earlier eye care access for patients with newly-diagnosed diabetes by Lieng, Monica K., Emami-Naeini, Parisa, Lee, Sophie C., Alber, Susan, Yiu, Glenn

“…Timely diagnosis of diabetic retinopathy is important in preventing vision loss. This study aims to determine if remote retinal imaging enables earlier eye…”
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EGFR Activation Mediates Inhibition of Axon Regeneration by Myelin and Chondroitin Sulfate Proteoglycans by Koprivica, Vuk, Cho, Kin-Sang, Park, Jong Bae, Yiu, Glenn, Atwal, Jasvinder, Gore, Bryan, Kim, Jieun A, Lin, Estelle, Tessier-Lavigne, Marc, Chen, Dong Feng, He, Zhigang

“…Inhibitory molecules associated with myelin and the glial scar limit axon regeneration in the adult central nervous system (CNS), but the underlying signaling…”
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Factors Impacting Efficacy of AAV-Mediated CRISPR-Based Genome Editing for Treatment of Choroidal Neovascularization by Chung, Sook Hyun, Mollhoff, Iris Natalie, Nguyen, Uyen, Nguyen, Amy, Stucka, Natalie, Tieu, Eric, Manna, Suman, Meleppat, Ratheesh Kumar, Zhang, Pengfei, Nguyen, Emerald Lovece, Fong, Jared, Zawadzki, Robert, Yiu, Glenn

“…Frequent injections of anti-vascular endothelial growth factor (anti-VEGF) agents are a clinical burden for patients with neovascular age-related macular…”
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CRISPR Technology for Ocular Angiogenesis by Chung, Sook Hyun, Sin, Tzu-Ni, Ngo, Taylor, Yiu, Glenn

“…Among genome engineering tools, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-based approaches have been widely adopted for translational…”
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Retinal dystrophies: A look beyond the eyes by Tang, Vincent Duong, Egense, Alena, Yiu, Glenn, Meyers, Elijah, Moshiri, Ala, Shankar, Suma P.

“…To illustrate the importance of systemic evaluation in retinal dystrophies through examples of Alstrom syndrome, Bardet Biedl syndrome, and Refsum disease…”
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The Management of Retinal Detachment: Techniques and Perspectives 2018 by Moisseiev, Elad, Loewenstein, Anat, Moshiri, Ala, Yiu, Glenn

“…The mean time for the occurrence of retinal detachment following cataract surgery was 1.5–2.3 years, and the authors suggest that proper timing of long-term…”
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Role of Tractional Forces and Internal Limiting Membrane in Macular Hole Formation: Insights from Intraoperative Optical Coherence Tomography by Moisseiev, Elad, Yiu, Glenn

“…We report the case of a 69-year-old patient who underwent vitrectomy for vitreomacular traction (VMT) and developed a postoperative macular hole that was…”
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