Search Results - "Yisong Shu"
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Anti-inflammatory effects of Zhishi and Zhiqiao revealed by network pharmacology integrated with molecular mechanism and metabolomics studies
Published in Phytomedicine (Stuttgart) (15-11-2018)“…The inflammatory response has a complex pathogenesis; thus, it is a critical contributor to the development and complication of many diseases. Zhishi and…”
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Natural small molecule self-assembled hydrogel inhibited tumor growth and lung metastasis of 4T1 breast cancer by regulating the CXCL1/2-S100A8/9 axis
Published in Materials & design (01-01-2023)“…[Display omitted] •The natural small molecule self-assembled hydrogel of GK-GA was designed in a one-step “green” approach for breast cancer treatments.•The…”
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Treatment of Rheumatoid Arthritis Using Combination of Methotrexate and Tripterygium Glycosides Tablets-A Quantitative Plasma Pharmacochemical and Pseudotargeted Metabolomic Approach
Published in Frontiers in pharmacology (09-10-2018)“…Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by chronic destructive synovitis and is associated with progressive disability,…”
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Design, synthesis and cytotoxic evaluation of novel betulonic acid-diazine derivatives as potential antitumor agents
Published in Frontiers in chemistry (06-09-2022)“…With the purpose to improve antiproliferative activity, 26 new betulonic acid-diazine derivatives were designed and synthesized from betulinic acid. The…”
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Pharmaceutical prospects of naturally occurring quinazolinone and its derivatives
Published in Fitoterapia (01-06-2017)“…Quinazolinones belong to a family of heterocyclic nitrogen compounds that have attracted increasing interest because of their broad spectrum of biological…”
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Characteristic chemical profile of Juhe Fang extract with lipid-lowering properties
Published in Journal of Traditional Chinese Medical Sciences (01-09-2020)“…Objective: The objective of this study was to verify the lipid-lowering effect of Juhe Fang extract (JHFE) and to determine its characteristic chemical profile…”
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Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health
Published in BMC chemistry (24-12-2015)“…Citrus fruits, which are cultivated worldwide, have been recognized as some of the most high-consumption fruits in terms of energy, nutrients and health…”
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Hepatoprotective Effect of Citrus aurantium L. Against APAP-induced Liver Injury by Regulating Liver Lipid Metabolism and Apoptosis
Published in International journal of biological sciences (01-01-2020)“…Acetaminophen (APAP) refers to a medication used to manage pain and fever symptoms, but it always causes liver injury when overdosed. Zhishi, dried young fruit…”
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Integrated and global pseudotargeted metabolomics strategy applied to screening for quality control markers of Citrus TCMs
Published in Analytical and bioanalytical chemistry (01-08-2017)“…Traditional Chinese medicine (TCM) exerts its therapeutic effect in a holistic fashion with the synergistic function of multiple characteristic constituents…”
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Natural diterpene carrier-free hydrogel enhances antigen presentation and intensifies T cell activation for tumor immunotherapy
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-11-2024)“…•The co-assembly of lipophilic diterpenoid hydrogels was developed for chemotherapy-enhanced antitumor immunotherapy.•KEEM enhances immunotherapy efficacy by…”
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A new approach to examining the extraction process of Zhishi and Zhiqiao considering the synergistic effect of complex mixtures by PAMPA
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-11-2018)“…Zhishi (ZS) and Zhiqiao (ZQ) are two important traditional Chinese medicines (TCMs) that exert various pharmacological functions due to their active…”
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A single marker choice strategy in simultaneous characterization and quantification of multiple components by rapid resolution liquid chromatography coupled with triple quadrupole tandem mass spectrometry (RRLC-QqQ-MS)
Published in Journal of pharmaceutical and biomedical analysis (30-05-2016)“…[Display omitted] •SSDMC method is an efficient technique for quality control of TCMs.•RRLC-QqQ-MS methods were firstly applied in SSDMC analysis.•An improved…”
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Synergistic enhancement and hepatoprotective effect of combination of total phenolic extracts of Citrus aurantium L. and methotrexate for treatment of rheumatoid arthritis
Published in Phytotherapy research (01-04-2019)“…Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder characterized by joint destruction and bone damage. Methotrexate (MTX) is recommended as the…”
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Preparation and quantification of the total phenolic products in Citrus fruit using solid-phase extraction coupled with high-performance liquid chromatography with diode array and UV detection
Published in Journal of separation science (01-10-2016)“…Citrus fruit is an important health‐promoting food that is rich in dietary phenolic metabolites. Traditional Chinese medicines, such as Zhishi and Zhiqiao,…”
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Hepatoprotective Effect ofCitrus aurantium L. Against APAP-induced Liver Injury by Regulating Liver Lipid Metabolism and Apoptosis
Published in International journal of biological sciences (01-01-2020)“…Acetaminophen (APAP) refers to a medication used to manage pain and fever symptoms, but it always causes liver injury when overdosed. Zhishi, dried young fruit…”
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Journal Article