Search Results - "Yipp, Bryan"

NETosis: how vital is it? by Yipp, Bryan G., Kubes, Paul

“…In this review, we examine the evidence that neutrophil extracellular traps (NETs) play a critical role in innate immunity. We summarize how NETs are formed in…”
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Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis by McDonald, Braedon, Urrutia, Rossana, Yipp, Bryan G., Jenne, Craig N., Kubes, Paul

“…During the systemic inflammatory response of severe sepsis, neutrophils accumulate in the liver microcirculation, but their functional significance is largely…”
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Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19 by Sinha, Sarthak, Rosin, Nicole L., Arora, Rohit, Labit, Elodie, Jaffer, Arzina, Cao, Leslie, Farias, Raquel, Nguyen, Angela P., de Almeida, Luiz G. N., Dufour, Antoine, Bromley, Amy, McDonald, Braedon, Gillrie, Mark R., Fritzler, Marvin J., Yipp, Bryan G., Biernaskie, Jeff

“…Although critical for host defense, innate immune cells are also pathologic drivers of acute respiratory distress syndrome (ARDS). Innate immune dynamics…”
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Virus-associated fungal infections and lost immune resistance by Sarden, Nicole, Yipp, Bryan G.

“…Emerging globally recognized issues of deadly fungal infections have been highlighted by the identification of virus-associated fungal infections.Neutrophils…”
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PGC-1α mediates a metabolic host defense response in human airway epithelium during rhinovirus infections by Michi, Aubrey N., Yipp, Bryan G., Dufour, Antoine, Lopes, Fernando, Proud, David

“…Human rhinoviruses (HRV) are common cold viruses associated with exacerbations of lower airways diseases. Although viral induced epithelial damage mediates…”
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Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia by Baral, Pankaj, Umans, Benjamin D, Li, Lu, Wallrapp, Antonia, Bist, Meghna, Kirschbaum, Talia, Wei, Yibing, Zhou, Yan, Kuchroo, Vijay K, Burkett, Patrick R, Yipp, Bryan G, Liberles, Stephen D, Chiu, Isaac M

“…Nociceptor sensory neurons suppress innate immunity during bacterial lung infection. Lung-innervating nociceptor sensory neurons detect noxious or harmful…”
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Neutrophils are itching to specialize by Hiroki, Carlos H, Yipp, Bryan G

“…Neutrophils are heterogeneous, but the mechanisms underlying their ability to polarize remain unclear. In this issue of Immunity, Gour et al. demonstrate that…”
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Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo by Yipp, Bryan G, Petri, Björn, Salina, Davide, Jenne, Craig N, Scott, Brittney N V, Zbytnuik, Lori D, Pittman, Keir, Asaduzzaman, Muhammad, Wu, Kaiyu, Meijndert, H Christopher, Malawista, Stephen E, de Boisfleury Chevance, Anne, Zhang, Kunyan, Conly, John, Kubes, Paul

“…Bacteria can be trapped by neutrophil extracellular traps (NETs) in vitro , but their relevance in vivo is uncertain, in part because NETs are thought to be…”
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Bacterial cyclic diguanylate signaling networks sense temperature by Almblad, Henrik, Randall, Trevor E., Liu, Fanny, Leblanc, Katherine, Groves, Ryan A., Kittichotirat, Weerayuth, Winsor, Geoffrey L., Fournier, Nicolas, Au, Emily, Groizeleau, Julie, Rich, Jacquelyn D., Lou, Yuefei, Granton, Elise, Jennings, Laura K., Singletary, Larissa A., Winstone, Tara M. L., Good, Nathan M., Bumgarner, Roger E., Hynes, Michael F., Singh, Manu, Stietz, Maria Silvina, Brinkman, Fiona S. L., Kumar, Ayush, Brassinga, Ann Karen Cornelia, Parsek, Matthew R., Tseng, Boo Shan, Lewis, Ian A., Yipp, Bryan G., MacCallum, Justin L., Harrison, Joe Jonathan

“…Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, we identify a thermosensory…”
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The Lung Microvasculature Is a Functional Immune Niche by Granton, Elise, Kim, Jung Hwan, Podstawka, John, Yipp, Bryan G.

“…Lung capillaries, best known for vital gas exchange, also contribute to neutrophil margination, a phenomenon resulting in large numbers of pulmonary vascular…”
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Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection by Snarr, Brendan D, St-Pierre, Guillaume, Ralph, Benjamin, Lehoux, Mélanie, Sato, Yukiko, Rancourt, Ann, Takazono, Takahiro, Baistrocchi, Shane R, Corsini, Rachel, Cheng, Matthew P, Sugrue, Michele, Baden, Lindsey R, Izumikawa, Koichi, Mukae, Hiroshi, Wingard, John R, King, Irah L, Divangahi, Maziar, Satoh, Masahiko S, Yipp, Bryan G, Sato, Sachiko, Sheppard, Donald C

“…Aspergillus fumigatus is an opportunistic mold that infects patients who are immunocompromised or have chronic lung disease, causing significant morbidity and…”
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A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus by Pilsczek, Florian H, Salina, Davide, Poon, Karen K H, Fahey, Candace, Yipp, Bryan G, Sibley, Christopher D, Robbins, Stephen M, Green, Francis H Y, Surette, Mike G, Sugai, Motoyuki, Bowden, M Gabriela, Hussain, Muzaffar, Zhang, Kunyan, Kubes, Paul

“…Neutrophil extracellular traps (NETs) are webs of DNA covered with antimicrobial molecules that constitute a newly described killing mechanism in innate immune…”
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Antibodies against neutrophil LY6G do not inhibit leukocyte recruitment in mice in vivo by Yipp, Bryan G., Kubes, Paul

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Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE by Pernet, Erwan, Sun, Sarah, Sarden, Nicole, Gona, Saideep, Nguyen, Angela, Khan, Nargis, Mawhinney, Martin, Tran, Kim A., Chronopoulos, Julia, Amberkar, Dnyandeo, Sadeghi, Mina, Grant, Alexandre, Wali, Shradha, Prevel, Renaud, Ding, Jun, Martin, James G., Thanabalasuriar, Ajitha, Yipp, Bryan G., Barreiro, Luis B., Divangahi, Maziar

“…Resident-tissue macrophages (RTMs) arise from embryonic precursors 1 , 2 , yet the developmental signals that shape their longevity remain largely unknown…”
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Neutrophil swarming: Is a good offense the best defense? by Brown, Luke, Yipp, Bryan G.

“…The phenomenon of swarming has long been observed in nature as a strategic event that serves as a good offense toward prey and predators. Imaging studies have…”
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Leukotriene B4-Mediated Neutrophil Recruitment Causes Pulmonary Capillaritis during Lethal Fungal Sepsis by Lee, Esther K.S., Gillrie, Mark R., Li, Lu, Arnason, Jason W., Kim, Jung Hwan, Babes, Liane, Lou, Yuefei, Sanati-Nezhad, Amir, Kyei, Stephen K., Kelly, Margaret M., Mody, Christopher H., Ho, May, Yipp, Bryan G.

“…Candida albicans bloodstream infection causes fungal septicaemia and death in over half of afflicted patients. Polymorphonuclear leukocytes (PMN) mediate…”
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Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver by Choudhury, Saurav Roy, Babes, Liane, Rahn, Jennifer J., Ahn, Bo-Young, Goring, Kimberly-Ann R., King, Jennifer C., Lau, Arthur, Petri, Björn, Hao, Xiaoguang, Chojnacki, Andrew K., Thanabalasuriar, Ajitha, McAvoy, Erin F., Tabariès, Sébastien, Schraeder, Christoph, Patel, Kamala D., Siegel, Peter M., Kopciuk, Karen A., Schriemer, David C., Muruve, Daniel A., Kelly, Margaret M., Yipp, Bryan G., Kubes, Paul, Robbins, Stephen M., Senger, Donna L.

“…A hallmark feature of inflammation is the orchestrated recruitment of neutrophils from the bloodstream into inflamed tissue. Although selectins and integrins…”
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Aged polymorphonuclear leukocytes cause fibrotic interstitial lung disease in the absence of regulation by B cells by Kim, Jung Hwan, Podstawka, John, Lou, Yuefei, Li, Lu, Lee, Esther K. S., Divangahi, Maziar, Petri, Björn, Jirik, Frank R., Kelly, Margaret M., Yipp, Bryan G.

“…Pulmonary immunity requires tight regulation, as interstitial inflammation can compromise gas exchange and lead to respiratory failure. Here we found a greater…”
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Marginating transitional B cells modulate neutrophils in the lung during inflammation and pneumonia by Podstawka, John, Sinha, Sarthak, Hiroki, Carlos H, Sarden, Nicole, Granton, Elise, Labit, Elodie, Kim, Jung Hwan, Andonegui, Graciela, Lou, Yuefei, Snarr, Brendan D, Sheppard, Donald C, Rosin, Nicole L, Biernaskie, Jeff, Yipp, Bryan G

“…Pulmonary innate immunity is required for host defense; however, excessive neutrophil inflammation can cause life-threatening acute lung injury. B lymphocytes…”
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Innate Receptors Expression by Lung Nociceptors: Impact on COVID-19 and Aging by Hiroki, Carlos H, Sarden, Nicole, Hassanabad, Mortaza F, Yipp, Bryan G

“…The lungs are constantly exposed to non-sterile air which carries harmful threats, such as particles and pathogens. Nonetheless, this organ is equipped with…”
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