Search Results - "Yip, Kenneth"

Targeting metabolic dysregulation for fibrosis therapy by Zhao, Xiao, Kwan, Jennifer Yin Yee, Yip, Kenneth, Liu, Peter P., Liu, Fei-Fei

“…Fibrosis is the abnormal deposition of extracellular matrix, which can lead to organ dysfunction, morbidity, and death. The disease burden caused by fibrosis…”
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HPV Associated Head and Neck Cancer by Spence, Tara, Bruce, Jeff, Yip, Kenneth W, Liu, Fei-Fei

“…Head and neck cancers (HNCs) are a highly heterogeneous group of tumours that are associated with diverse clinical outcomes. Recent evidence has demonstrated…”
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MicroRNAs in extracellular vesicles: potential cancer biomarkers by Kinoshita, Takashi, Yip, Kenneth W, Spence, Tara, Liu, Fei-Fei

“…Extracellular vesicles (EV) are small membrane-bound structures that are secreted by various cell types, including tumor cells. Recent studies have shown that…”
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Hypothalamic AMPK as a Mediator of Hormonal Regulation of Energy Balance by Wang, Baile, Cheng, Kenneth King-Yip

“…As a cellular energy sensor and regulator, adenosine monophosphate (AMP)-activated protein kinase (AMPK) plays a pivotal role in the regulation of energy…”
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Nasopharyngeal Cancer: Molecular Landscape by Bruce, Jeff P, Yip, Kenneth, Bratman, Scott V, Ito, Emma, Liu, Fei-Fei

“…Nasopharyngeal carcinoma (NPC) is a unique epithelial malignancy arising from the superior aspect of the pharyngeal mucosal space, associated with latent…”
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Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma by Liu, Zhuohao, Zhou, Jiayi, Yang, Xinzhi, Liu, Yuchen, Zou, Chang, Lv, Wen, Chen, Cheng, Cheng, Kenneth King-Yip, Chen, Tao, Chang, Lung-Ji, Wu, Dinglan, Mao, Jie

“…This study aimed to validate whether infusion of GD2-specific fourth-generation safety-designed chimeric antigen receptor (4SCAR)-T cells is safe and whether…”
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Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis by Inoue, Minoru, Nakashima, Ryota, Enomoto, Masahiro, Koike, Yuhki, Zhao, Xiao, Yip, Kenneth, Huang, Shao Hui, Waldron, John N., Ikura, Mitsuhiko, Liu, Fei-Fei, Bratman, Scott V.

“…Neutrophil extracellular traps (NETs) promote cancer metastasis in preclinical models following massive exogenous inflammatory stimuli. It remains unknown…”
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NLRP3 Inflammasome Activation in Adipose Tissues and Its Implications on Metabolic Diseases by Wu, Kelvin Ka-Lok, Cheung, Samson Wing-Ming, Cheng, Kenneth King-Yip

“…Adipose tissue is an active endocrine and immune organ that controls systemic immunometabolism via multiple pathways. Diverse immune cell populations reside in…”
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Monolithic Integration of GaN-on-Sapphire Light-Emitting Diodes, Photodetectors, and Waveguides by Kwai Hei Li, Yuk Fai Cheung, Wai Yuen Fu, Wong, Kenneth Kin-Yip, Hoi Wai Choi

“…We demonstrate the monolithic integration of light-emitting diodes (LEDs), photodetectors (PDs), and waveguides on a GaN-on-sapphire wafer. The InGaN/GaN…”
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The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages by Wu, Kelvin Ka Lok, Long, KeKao, Lin, Huige, Siu, Parco Ming Fai, Hoo, Ruby Lai Chong, Ye, Dewei, Xu, Aimin, Cheng, Kenneth King Yip

“…Although mitophagy is known to restrict NLRP3 inflammasome activation, the underlying regulatory mechanism remains poorly characterized. Here we describe a…”
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MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma by Bissey, Pierre-Antoine, Teng, Mona, Law, Jacqueline H, Shi, Wei, Bruce, Jeff P, Petit, Valentin, Tsao, Sai W, Yip, Kenneth W, Liu, Fei-Fei

“…A major cause of disease-related death in nasopharyngeal carcinoma (NPC) is the development of distant metastasis (DM) despite combination chemoradiotherapy…”
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The Novel Perspectives of Adipokines on Brain Health by Lee, Thomas Ho-Yin, Cheng, Kenneth King-Yip, Hoo, Ruby Lai-Chong, Siu, Parco Ming-Fai, Yau, Suk-Yu

“…First seen as a fat-storage tissue, the adipose tissue is considered as a critical player in the endocrine system. Precisely, adipose tissue can produce an…”
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The microRNA-218~Survivin axis regulates migration, invasion, and lymph node metastasis in cervical cancer by Kogo, Ryunosuke, How, Christine, Chaudary, Naz, Bruce, Jeff, Shi, Wei, Hill, Richard P, Zahedi, Payam, Yip, Kenneth W, Liu, Fei-Fei

“…Cervical cancer is the third most common cancer in women worldwide. In the present study, global microRNA profiling for 79 cervical cancer patient samples led…”
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miR-18a promotes glioblastoma development by down-regulating ALOXE3-mediated ferroptotic and anti-migration activities by Yang, Xinzhi, Liu, Jiangang, Wang, Chenci, Cheng, Kenneth King-yip, Xu, Hongchao, Li, Qingzhong, Hua, Tian, Jiang, Xue, Sheng, Lili, Mao, Jie, Liu, Zhuohao

“…The development of glioblastoma (GBM) is typically accompanied by marked changes in lipid metabolism. Oxylipins and their catalyzed enzymes lipoxygenases…”
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Radiomic Biomarkers to Refine Risk Models for Distant Metastasis in HPV-related Oropharyngeal Carcinoma by Kwan, Jennifer Yin Yee, Su, Jie, Huang, Shao Hui, Ghoraie, Laleh S., Xu, Wei, Chan, Biu, Yip, Kenneth W., Giuliani, Meredith, Bayley, Andrew, Kim, John, Hope, Andrew J., Ringash, Jolie, Cho, John, McNiven, Andrea, Hansen, Aaron, Goldstein, David, de Almeida, John R., Aerts, Hugo J., Waldron, John N., Haibe-Kains, Benjamin, O'Sullivan, Brian, Bratman, Scott V., Liu, Fei-Fei

“…Distant metastasis (DM) is the main cause of death for patients with human papillomavirus (HPV)–related oropharyngeal cancers (OPCs); yet, there are few…”
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KIF5B plays important roles in dendritic spine plasticity and dendritic localization of PSD95 and FMRP in the mouse cortex in vivo by Fok, Albert Hiu Ka, Huang, Yuhua, So, Beth Wing Lam, Zheng, Qiyu, Tse, Chun Sing Carlos, Li, Xiaoyang, Wong, Kenneth Kin-Yip, Huang, Jiandong, Lai, Kwok-On, Lai, Cora Sau Wan

“…Kinesin 1 (KIF5) is one major type of motor protein in neurons, but its members’ function in the intact brain remains less studied. Using in vivo two-photon…”
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Metabolic regulation of dermal fibroblasts contributes to skin extracellular matrix homeostasis and fibrosis by Zhao, Xiao, Psarianos, Pamela, Ghoraie, Laleh Soltan, Yip, Kenneth, Goldstein, David, Gilbert, Ralph, Witterick, Ian, Pang, Hilary, Hussain, Ali, Lee, Ju Hee, Williams, Justin, Bratman, Scott V., Ailles, Laurie, Haibe-Kains, Benjamin, Liu, Fei-Fei

“…Extracellular matrix (ECM) homeostasis is essential for normal tissue function, and its disruption by iatrogenic injury, trauma, or disease results in…”
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Fetuin-A levels and risk of type 2 diabetes mellitus: a systematic review and meta-analysis by Guo, Vivian Yawei, Cao, Bing, Cai, Chunyan, Cheng, Kenneth King-yip, Cheung, Bernard Man Yung

“…Aims Fetuin-A has been linked to insulin resistance and obesity. Its role in the pathogenesis of type 2 diabetes (T2DM) has also been discussed. We aimed to…”
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Editorial: Hallmark of cancer: Resisting cell death by Zhu, Yichao, Yang, Risheng, Law, Jacqueline H., Khan, Muhammad, Yip, Kenneth W., Sun, Qiang

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CD8+ Tumor-Infiltrating Lymphocyte Abundance Is a Positive Prognostic Indicator in Nasopharyngeal Cancer by Shi, Wei, Fijardo, Mackenzie, Bruce, Jeff P, Su, Jie, Xu, Wei, Bell, Rachel, Bissey, Pierre-Antoine, Hui, Angela B Y, Waldron, John, Pugh, Trevor J, Yip, Kenneth W, Liu, Fei-Fei

“…Tumor-infiltrating lymphocytes (TIL) are immune cell populations found within tumors, critical in the antigen-specific host immune response. In this study, we…”
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