Search Results - "Yinghui, CHEN"
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Geometry Relaxation-Induced Large Stokes Shift in Red-Emitting Borondipyrromethenes (BODIPY) and Applications in Fluorescent Thiol Probes
Published in Journal of organic chemistry (02-03-2012)“…2-Thienyl and 2,6-bisthienyl BODIPY derivatives (BS-SS and BS-DS) were prepared that show intense absorption (ε = 65000 M–1 cm–1 at 507 nm) and a large Stokes…”
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An Overview of Pickering Emulsions: Solid-Particle Materials, Classification, Morphology, and Applications
Published in Frontiers in pharmacology (23-05-2017)“…Pickering emulsion, a kind of emulsion stabilized only by solid particles locating at oil-water interface, has been discovered a century ago, while being…”
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3
An end-to-end framework for the prediction of protein structure and fitness from single sequence
Published in Nature communications (27-08-2024)“…Significant research progress has been made in the field of protein structure and fitness prediction. Particularly, single-sequence-based structure prediction…”
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4
Inflammation: A Network in the Pathogenesis of Status Epilepticus
Published in Frontiers in molecular neuroscience (05-10-2018)“…Status epilepticus (SE) is an abnormally prolonged or recurrent epileptic seizure that is a serious, life-threatening medical emergency. Notably, it requires…”
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LncRNA Snhg5 Attenuates Status Epilepticus Induced Inflammation through Regulating NF-κΒ Signaling Pathway
Published in Biological & pharmaceutical bulletin (01-01-2022)“…Status epilepticus (SE) induced inflammation plays an important role in the pathogenesis of SE. Long non-coding RNA small nucleolar RNA host gene 5 (lncRNA…”
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Inhibition of p38 mitogen‐activated protein kinase signaling reduces multidrug transporter activity and anti‐epileptic drug resistance in refractory epileptic rats
Published in Journal of neurochemistry (01-03-2016)“…It is widely recognized that P‐glycoprotein (P‐gp) mediates drug resistance in refractory epilepsy. However, the molecular mechanism underlying the…”
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Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases
Published in Frontiers in immunology (16-02-2017)“…microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by base pairing with their target messenger RNAs. Dysregulation of miRNAs is…”
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Pathophysiology and Clinical Utility of Non-coding RNAs in Epilepsy
Published in Frontiers in molecular neuroscience (10-08-2017)“…Epilepsy is a common neurologic disorder. The underlying pathological processes include synaptic strength, inflammation, ion channels, and apoptosis. Acting as…”
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The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats
Published in Frontiers in pharmacology (10-07-2018)“…Currently, there are no effective treatments for diabetes-related cognitive dysfunction. Astaxanthin (AST), the most powerful antioxidant in nature, exhibits…”
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MicroRNA-146a-5p Downregulates the Expression of P-Glycoprotein in Rats with Lithium–Pilocarpine-Induced Status Epilepticus
Published in Biological & pharmaceutical bulletin (01-05-2019)“…Increasing evidence supports that the efflux transporters, especially P-glycoprotein (P-gp), have vital roles on drug resistance in epilepsy. Overexpression of…”
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Advances in Roles of miR-132 in the Nervous System
Published in Frontiers in pharmacology (25-10-2017)“…miR-132 is an endogenous small RNA and controls post-transcriptional regulation of gene expression via controlled degradation of mRNA or transcription…”
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Thymoquinone Alleviates the Experimental Diabetic Peripheral Neuropathy by Modulation of Inflammation
Published in Scientific reports (22-08-2016)“…Thymoquinone has been reported to exhibit antioxidant and anti-inflammatory effects. Inflammation plays an important role in pathogenesis of diabetic…”
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MicroRNA-298 Reverses Multidrug Resistance to Antiepileptic Drugs by Suppressing MDR1/P-gp Expression in vitro
Published in Frontiers in neuroscience (28-08-2018)“…P-glycoprotein (P-gp), a critical multidrug transporter, recognizes and transports various antiepileptic drugs (AEDs) through the blood-brain barrier (BBB)…”
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14
Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy
Published in Endocrine Journal (01-01-2024)“…Dyslipidemia has been considered a risk factor for diabetic peripheral neuropathy. Proprotein convertase subtilisin-like/Kexin 9 inhibitor (PCSK9) inhibitors…”
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Long Non-coding RNA KCNQ1OT1 Contributes to Antiepileptic Drug Resistance Through the miR-138-5p/ABCB1 Axis in vitro
Published in Frontiers in neuroscience (17-12-2019)“…Compelling evidence has verified that long non-coding RNAs (lncRNAs) play a critical role on drug resistance in various diseases, especially cancer. However,…”
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MicroRNA-146a: A Comprehensive Indicator of Inflammation and Oxidative Stress Status Induced in the Brain of Chronic T2DM Rats
Published in Frontiers in pharmacology (14-05-2018)“…It was demonstrated that inflammation and oxidative stress induced by hyperglycemia were closely associated with alteration of miR-146a. Here, we investigated…”
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Yeast polysaccharide supplementation: impact on lactation, growth, immunity, and gut microbiota in Dezhou donkeys
Published in Frontiers in microbiology (09-11-2023)“…Introduction The Dezhou donkey, a prominent Chinese breed, is known for its remarkable size, rapid growth, and resilience to tough feeding conditions, and…”
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Atorvastatin Induces Mitochondria-Dependent Ferroptosis via the Modulation of Nrf2-xCT/GPx4 Axis
Published in Frontiers in cell and developmental biology (03-03-2022)“…As one of the cornerstones of clinical cardiovascular disease treatment, statins have an extensive range of applications. However, statins commonly used have…”
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The Neuroprotective Effect of Astaxanthin on Pilocarpine-Induced Status Epilepticus in Rats
Published in Frontiers in cellular neuroscience (29-03-2019)“…Cognitive dysfunction is one of the serious complications induced by status epilepticus (SE), which has a significant negative impact on patients' quality of…”
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Enhancing bovine immune, antioxidant and anti-inflammatory responses with vitamins, rumen-protected amino acids, and trace minerals to prevent periparturient mastitis
Published in Frontiers in immunology (08-01-2024)“…Mastitis, the inflammatory condition of mammary glands, has been closely associated with immune suppression and imbalances between antioxidants and free…”
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