Search Results - "Ying, Jianming"

Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer by Wang, Shuo, Qu, Yuan, Xia, Pengyan, Chen, Yi, Zhu, Xiaoxiao, Zhang, Jing, Wang, Guan, Tian, Yong, Ying, Jianming, Fan, Zusen

“…Innate lymphoid cells (ILCs) reside in mucosal surfaces to potentiate immune responses, sustain mucosal integrity and maintain tissue homeostasis. However, how…”
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Intergenic Breakpoints Identified by DNA Sequencing Confound Targetable Kinase Fusion Detection in NSCLC by Li, Weihua, Liu, Yutao, Li, Wenbin, Chen, Li, Ying, Jianming

“…Next-generation sequencing (NGS) based on genomic DNA has been widely applied for gene rearrangement detection in patients with NSCLC. However,…”
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Can CT-based radiomics signature predict KRAS/NRAS/BRAF mutations in colorectal cancer? by Yang, Lei, Dong, Di, Fang, Mengjie, Zhu, Yongbei, Zang, Yali, Liu, Zhenyu, Zhang, Hongmei, Ying, Jianming, Zhao, Xinming, Tian, Jie

“…Objectives To investigate whether CT-based radiomics signature can predict KRAS/NRAS/BRAF mutations in colorectal cancer (CRC). Methods This retrospective…”
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Identification and Validation of a Novel Signature Based on NK Cell Marker Genes to Predict Prognosis and Immunotherapy Response in Lung Adenocarcinoma by Integrated Analysis of Single-Cell and Bulk RNA-Sequencing by Song, Peng, Li, Wenbin, Guo, Lei, Ying, Jianming, Gao, Shugeng, He, Jie

“…Natural killer (NK) cells, the effectors of the innate immune system, have a remarkable influence on cancer prognosis and immunotherapy. In this study, a total…”
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Potential Unreliability of Uncommon ALK, ROS1, and RET Genomic Breakpoints in Predicting the Efficacy of Targeted Therapy in NSCLC by Li, Weihua, Guo, Lei, Liu, Yutao, Dong, Lin, Yang, Lin, Chen, Li, Liu, Kaihua, Shao, Yang, Ying, Jianming

“…Variable genomic breakpoints have been identified through the application of target-capture DNA next-generation sequencing (NGS) for ALK, ROS1, and RET fusion…”
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Primary and acquired EGFR T790M-mutant NSCLC patients identified by routine mutation testing show different characteristics but may both respond to osimertinib treatment by Li, Weihua, Qiu, Tian, Guo, Lei, Ling, Yun, Gao, Yibo, Ying, Jianming, He, Jie

“…Primary EGFR T790M mutation is occasionally identified by routine mutation testing in tyrosine kinase inhibitor (TKI)-naive patients with non-small cell lung…”
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Multiregion Sequencing Reveals the Genetic Heterogeneity and Evolutionary History of Osteosarcoma and Matched Pulmonary Metastases by Wang, Di, Niu, Xiaohui, Wang, Zhijie, Song, Cheng-Li, Huang, Zhen, Chen, Ke-Neng, Duan, Jianchun, Bai, Hua, Xu, Jiachen, Zhao, Jun, Wang, Yu, Zhuo, Minglei, Xie, X Sunney, Kang, Xiaozheng, Tian, Yanhua, Cai, Liangliang, Han, Jie-Fei, An, Tongtong, Sun, Yu, Gao, Shugeng, Zhao, Jun, Ying, Jianming, Wang, Luhua, He, Jie, Wang, Jie

“…: Osteosarcoma is the most common primary bone malignancy, and the lung is the most frequent site of metastasis. The limited understanding of the tumoral…”
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Variation of Programmed Death Ligand 1 Expression After Platinum-based Neoadjuvant Chemotherapy in Lung Cancer by Guo, Lei, Song, Peng, Xue, Xuemin, Guo, Changyuan, Han, Liankui, Fang, Qing, Ying, Jianming, Gao, Shugeng, Li, Wenbin

“…The effect of chemotherapy on programmed cell death-ligand 1 (PD-L1) expression has been previously studied in lung cancer, while the results remain…”
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Development and validation of nomograms for predicting axillary non-SLN metastases in breast cancer patients: A retrospective analysis by Lei, Huizi, Yuan, Pei, Guo, Changyuan, Ying, Jianming

“…The aim of this study was to develop a nomogram for predicting positive non-sentinel lymph nodes (non-SLNs) in positive SLN breast cancer patients and validate…”
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Progression patterns, resistant mechanisms and subsequent therapy for ALK-positive NSCLC in the era of second-generation ALK-TKIs by Wu, Lige, Zou, Zihua, Li, Yan, Hao, Xuezhi, Ying, Jianming, Li, Junling, Xing, Puyuan

“…In the era of second-generation ALK tyrosine kinase inhibitors (ALK-TKIs), there was a paucity of data regarding the progression patterns, resistant…”
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Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma by Yang, Zhenlin, Xu, Jiachen, Li, Lin, Li, Renda, Wang, Yalong, Tian, Yanhua, Guo, Wei, Wang, Zhijie, Tan, Fengwei, Ying, Jianming, Jiao, Yuchen, Gao, Shugeng, Wang, Jie, Gao, Yibo, He, Jie

“…Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of lung cancer with poor prognosis. Here, we perform multi-omics analysis of 56 PSC samples, 14 of…”
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Detection of ROS1 gene rearrangement in lung adenocarcinoma: comparison of IHC, FISH and real-time RT-PCR by Shan, Ling, Lian, Fang, Guo, Lei, Qiu, Tian, Ling, Yun, Ying, Jianming, Lin, Dongmei

“…To compare fluorescence in situ hybridization (FISH), immunohistochemistry (IHC) and quantitative real-time reverse transcription-PCR (qRT-PCR) assays for…”
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MET alterations detection platforms and clinical implications in solid tumors: a comprehensive review of literature by Yuan, Pei, Xue, Xuemin, Qiu, Tian, Ying, Jianming

“…alterations, including exon 14 skipping variants, amplification, overexpression, and fusion, play pivotal roles in primary tumorigenesis and acquired…”
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Immune-related histologic phenotype in pretreatment tumour biopsy predicts the efficacy of neoadjuvant anti-PD-1 treatment in squamous lung cancer by Yuan, Pei, Guo, Changyuan, Li, Lin, Ling, Yun, Guo, Lei, Ying, Jianming

“…Abstract Background Although neoadjuvant anti-PD-1 immunotherapies have shown good efficacy in non-small cell lung cancer (NSCLC) patients, there is still a…”
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Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy by Wang, Bingzhi, Zhu, Yongjian, Wang, Shaoming, Li, Zhuo, Wang, Long, Rao, Wei, Cheng, Na, Chen, Rongshan, Ying, Jianming, Xue, Liyan

“…Background Gastric adenocarcinoma is a highly heterogeneous malignancy with varying prognoses. In clinicopathological practice, we noticed a special tubular…”
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Reliability analysis of exonic-breakpoint fusions identified by DNA sequencing for predicting the efficacy of targeted therapy in non-small cell lung cancer by Li, Weihua, Wan, Rui, Guo, Lei, Chang, Geyun, Jiang, Dong, Meng, Lin, Ying, Jianming

“…Diverse genomic breakpoints of fusions that localize to intronic, exonic, or intergenic regions have been identified by DNA next-generation sequencing (NGS),…”
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Mutant-Allele Tumor Heterogeneity, a Favorable Biomarker to Assess Intra-Tumor Heterogeneity, in Advanced Lung Adenocarcinoma by Wu, Xiaoxuan, Song, Peng, Guo, Lei, Ying, Jianming, Li, Wenbin

“…Background Intra-tumor heterogeneity (ITH) plays a vital role in drug resistance and recurrence of lung cancer. We used a mutant-allele tumor heterogeneity…”
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HER2 expression and relevant clinicopathological features in gastric and gastroesophageal junction adenocarcinoma in a Chinese population by Shan, Ling, Ying, Jianming, Lu, Ning

“…With varied immunohistochemistry scoring criteria and patient cohorts, HER2-positivity rates in gastric cancer (GC) and gastroesophageal junction (GEJ)…”
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Multi-dimensional characterization of immunological profiles in small cell lung cancer uncovers clinically relevant immune subtypes with distinct prognoses and therapeutic vulnerabilities by Yang, Lin, Zhang, Zicheng, Dong, Jiyan, Zhang, Yibo, Yang, Zijian, Guo, Yiying, Sun, Xujie, Li, Junling, Xing, Puyuan, Ying, Jianming, Zhou, Meng

“…Small-cell lung cancer (SCLC) is generally considered a 'homogenous' disease, with little documented inter-tumor heterogeneity in treatment guidance or…”
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Subjecting appropriate lung adenocarcinoma samples to next‐generation sequencing‐based molecular testing: challenges and possible solutions by Li, Weihua, Qiu, Tian, Ling, Yun, Gao, Shugeng, Ying, Jianming

“…Next‐generation sequencing (NGS) has recently been rapidly adopted in the molecular diagnosis of cancer, but it still faces some obstacles. In this study, 665…”
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